Results 91 to 100 of about 6,454,413 (294)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Hereditary Spastic Paraplegia (HSP) comprises a group of rare genetic diseases characterized by length‐dependent axonal degeneration of the corticospinal tracts and dorsal columns, whose main clinical feature is spastic gait. Pathogenic variants in the SPG4 gene cause Spastic Paraplegia Type 4 (SPG4‐HSP), the most common form of HSP.
Gaia Fattorini +12 more
wiley +1 more source
Development of Intra-Individual Process Metrics in a Serious-Video Game Intervention for ADHD
Data(1) Background: Attention-deficit/hyperactivity disorder (ADHD) is characterized by persistent difficulties related to inattention, hyperactivity, and impulsivity, which significantly impair daily functioning.
Marina Martin-Moratinos +5 more
doaj +1 more source
Summary of subgroup analysis results for choice reaction time intra-individual variability studies.
, 2012 Note. CRT IIV = choice reaction time intra-individual variability, CV = coefficient of variation, ES = effect size (Cohen's d), ISD = intra-individual standard deviation, PI = preparatory interval.ap value for overall between subgroup heterogeneity.
Dominika Dykiert (127269) +3 more
core +1 more source
Intra- and interobserver variability of variables during exercise in ten subjects.
, 2023 Intra- and interobserver variability of variables during exercise in ten subjects.
Ellen Ostenfeld (3799837) +5 more
core +1 more source
Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay +15 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate the diagnostic accuracy of glial fibrillary acidic protein (GFAP) measured in dried plasma spots versus conventional plasma‐ and serum‐GFAP testing for assessment of disease severity in aquaporin‐4 immunoglobulin G–positive neuromyelitis optica spectrum disorder (AQP4‐IgG+ NMOSD).
Felix Wohlrab +19 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a devastating neurological disease that lacks serological biomarkers that can accurately reflect disease activity. We established a live cell‐based assay (LCBA) using serum with endogenous complement to quantify the overall cytotoxicity, offering a novel functional tool for monitoring
Xiaona Xu +10 more
wiley +1 more source
BMC PsychologyBackground Children’s cognitive performance fluctuates across multiple timescales. However, fluctuations have often been neglected in favour of research into average cognitive performance, limiting the unique insights into cognitive abilities and ...
Ilse E. J. I. Coolen +10 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Blood biomarkers are increasingly critical for non‐invasive Alzheimer's Disease (AD) diagnostics and research but typically require on‐site processing. Remote point‐of‐care collection methods could enhance biomarker testing in clinical and research settings.
Sara Ho +9 more
wiley +1 more source
Cortisol in the first year of life: Normative values and intra-individual variability
, 2010 Contains fulltext : 90108.pdf (Publisher’s version ) (Open Access)Introduction: Many studies have incorporated cortisol measurements when studying infant development, but descriptions of normal development of basal cortisol levels in ...
Tollenaar, M.S. +9 more
core +1 more source