FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni +17 more
wiley +1 more source
Technical limitations often let dominant signals overshadow rare cell types and fine‐grained heterogeneity in spatial transcriptomics. SemanticST, a graph neural network using multi‐semantic graph fusion and a novel min‐cut loss, recovers these subtle patterns.
Roxana Zahedi +7 more
wiley +1 more source
Intra-individual variability in ancient plasmodium DNA recovery highlights need for enhanced sampling. [PDF]
Llanos-Lizcano A +10 more
europepmc +1 more source
Vision begins not with images but with change: the retina fires only when something moves, handing the brain a stream of spikes. A neuromorphic imaging system adopts the same strategy—an event sensor that sees like the retina, a spiking network that thinks like the brain—to track and reconstruct fully randomly moving targets through tissue (phantom ...
Ning Zhang, Arto Nurmikko
wiley +1 more source
Intra-individual variability in lipoprotein(a): the value of a repeat measure for reclassifying individuals at intermediate risk. [PDF]
Harb T +4 more
europepmc +1 more source
Algorithms to correct inter and intra individual variability
Algorithms to correct inter and intra individual ...
openaire +1 more source
Neuromorphic Devices and Computing for Sensing, Memory, and Control
This review introduces neuromorphic devices made from diverse materials. These devices mimic neuronal functions and architectures and, when integrated with artificial or biological computing, can form closed loops with neurons for pressure, optical, acoustic, and biochemical sensing and modulation.
Zhengguang Zhu +2 more
wiley +1 more source
Examining the Stability and Predictive Utility of Across- and Within-Domain Intra-Individual Variability in Mild Cognitive Impairment. [PDF]
DesRuisseaux LA, Guevara JE, Duff K.
europepmc +1 more source
Computationally Evidence‐Grounded Sequence‐First Design of Peptide Binders
BOND‐PEP enables controllable, sequence‐first peptide binder design by grounding generation in binding evidence retrieved for each target. It uses topology‐conditioned message passing to integrate relevant peptide examples with the target protein sequence, forming a residue‐level representation that guides the generation of diverse, target‐specific ...
Wenze Ding
wiley +1 more source
Executive Functioning Training for Reducing Cognitive Intra-Individual Variability in People Living with HIV: A Pilot Randomized, Controlled Trial Protocol. [PDF]
Odii IO +9 more
europepmc +1 more source

