Results 241 to 250 of about 6,454,413 (294)

Intra-individual variability of the electrocardiogram

, 2000
openaire   +1 more source

Bone Marrow Macrophage STING Signaling is a Direct Nexus Linking Marrow Adipose Expansion to NAD+ Depletion and Osteogenic Decline in Skeletal Aging

Advanced Science, EarlyView.
This study reveals that during skeletal aging, bone marrow adipocyte‐derived sDPP4 primes STING signaling in macrophages. In combination with mitochondrial DNA, this signaling activates CD38 and depletes local NAD+/NMN, thereby impairing osteogenesis.
Zhichao Li, Kuanhui Gao, Mengjie Wang, Songlin Liang, Dandan Li, Guoqing Tan, Haipeng Xue, Yujie Liu, Peng Zhang, Zhanwang Xu, Wenxiang Cheng, Yongjun Wang, Nianhu Li   +12 more
wiley   +1 more source

TGFBI Maintains Fibrocartilage Homeostasis by Restraining O‐GlcNAcylation to Inactivate and Destabilize ADAMTS16 in Temporomandibular Joint Osteoarthritis

Advanced Science, EarlyView.
TGFBI deficiency elevates O‐GlcNAcylation, promoting the transcriptional activation of ADAMTS16 and OGT‐mediated post‐translational modification of ADAMTS16 at Ser1170. This leads to its stabilization and accumulation, driving chondrocyte metabolic disorders and senescent phenotypes, ultimately resulting in fibrocartilage dysfunction and TMJOA ...
Xin Liu, Xinyue Luo, Jie Zhao, Ziyan Jiang, Jiayi Zhai, Taomin Zhu, Xueke Jia, Xiaohan Ma, Henghua Jiang, Huimin Li, Yaping Feng, Jin Ke, Xing Long   +12 more
wiley   +1 more source

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Intra-Individual Variability in Creativity

European Psychologist, 2022
Abstract. Individual differences perspectives have dominated the scientific study of creativity since the 1950’s. These perspectives, however, mainly emphasize group-level variations or inter-individual differences, with limited interest in individual-level variations. Yet, (1) group-level findings are often used to make inferences at the person-level,
openaire   +1 more source

Intra-Individual Variability in the Response to Anodal Transcranial Direct Current Stimulation

Clinical Neurophysiology, 2015
Artículos en revistasVariabilidad intra-individual en respuesta a la estimulación transcraneal eléctrica directa.Intra-individual variability in the response to anodal Transcranial Direct Current Stimulation.info:eu-repo/semantics ...
Miguel Fernández-del-Olmo, Juan Jose González-Henriquez, Binith Cheeran   +2 more
exaly   +1 more source

Intra-individual variability of fibrinogen levels

Journal of Clinical Epidemiology, 1997
Elevated fibrinogen concentrations are recognized as playing an important role in the pathogenesis of atherosclerosis. In the framework of a risk factor survey in 342 middle-aged working men, screened twice over a period of five months, plasma fibrinogen levels were found to be fairly unstable as large discrepancies between both measurements were ...
D, De Bacquer, G, De Backer, L, Braeckman, G, Baele   +3 more
openaire   +2 more sources