Results 51 to 60 of about 2,126,092 (91)
Malassezia (predominantly M. globosa) colonizes BCC tissues. In vitro fungal stimulation accelerates epithelial proliferation and modulates inflammatory/oxidative stress cascades potentially relevant to BCC biology. ABSTRACT Basal cell carcinoma (BCC) is the most common malignant skin tumor.
Xiaolei Zhu +5 more
wiley +1 more source
ABSTRACT Thymoma is the most common tumor of the anterior mediastinum. Approximately 20%–30% of patients with a thymoma develop myasthenia gravis (MG), and an additional one third may possess positive acetylcholine receptor (AChR) antibodies without MG.
Benjamin Claytor +5 more
wiley +1 more source
Comparison of pre-operative dGEMRIC imaging with intra-operative findings in femoroacetabular impingement: preliminary findings [PDF]
To study standard MRI and dGEMRIC in patients with symptomatic FAI undergoing surgical intervention and compare them with intra-operative findings to see if they were ...
Harish S. Hosalkar +11 more
core +2 more sources
Abstract Cardiovascular disease (CVD) remains the leading global cause of death, driven by complex mechanisms, in which chronic inflammation plays a central role. Inflammatory pathways contribute to all stages of CVD, from endothelial dysfunction and plaque formation to erosion, rupture and myocardial injury.
Shreya Mahabhashyam +4 more
wiley +1 more source
eCIRP released in the stroke brain binds to TLR4 expressed on microglia to induce miR‐155, which suppresses MafB, decreases MerTK and downstream signaling to impair efferocytosis of apoptotic neurons, worsening the acute stroke outcomes. Inhibition of eCIRP‐TLR4 interaction with small peptide C23 attenuates eCIRP‐induced microglial efferocytic ...
Dmitriy Lapin +3 more
wiley +1 more source
Natural product flavonoids have a multi‐target therapeutic intervention effect on osteoarthritis. They promote autophagy and cartilage synthesis while alleviating oxidative stress, inhibiting inflammation, and inhibiting matrix degradation. By restoring OPG/RANKL balance and regulating bone metabolism, these compounds synergistically delay the ...
Haibin Wang +6 more
wiley +1 more source
Reactive Oxygen Species in Breast Cancer: From Redox Dysregulation to ROS‐Responsive Therapeutics
ABSTRACT Breast cancer is the most frequently diagnosed malignancy among women worldwide, with 2.3 million new cases and approximately 670,000 deaths reported in 2022 alone. Despite advances in therapy, metastasis and acquired drug resistance remain major clinical challenges.
Marija Nikolovska +5 more
wiley +1 more source
Surgical stress response markedly increases sympathetic nerve activity and catecholamine concentrations. This may contribute to peripheral vasoconstriction, reduced wound perfusion and subsequent tissue hypoxia.
Niedermayr, M +6 more
core +1 more source
ABSTRACT Type 1 Diabetes (T1D) is an autoimmune disorder marked by the immune‐mediated destruction of pancreatic β‐cells, resulting in insulin deficiency and dysregulated glucose control. Current therapies—such as insulin replacement and artificial pancreas systems—manage symptoms but fail to restore endogenous β‐cell function or halt disease ...
Fatemeh Sabet Sarvestani +4 more
wiley +1 more source
Annual; 1997/2001-; "The Ohio Department of Health [and] Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, The Ohio State University."; Vol.
core

