Results 61 to 70 of about 1,675,350 (299)

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang   +8 more
wiley   +1 more source

Clinical Validation of Plasma p‐217tau in Neurological Diseases

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma p‐217tau is a minimally invasive but specific biomarker for diagnosing Alzheimer's disease (AD). However, its disease specificity remains to be clinically evaluated. We validated the reliability of the p‐217tau biomarker in 12 other neurological diseases.
Takeshi Kawarabayashi   +13 more
wiley   +1 more source

Vertical intra-industry trade and the EU accession: The case of Hungarian agri-food sector [PDF]

open access: yes, 2013
The aim of this paper is to examine the relationship between the factor endowment and the pattern of intra-industry trade. Our empirical analysis relates to Hungary’s intra-industry trade in agri-food products with 26 member states of the EU over the ...
Jámbor, Attila, Fertő, Imre
core  

Refining intra-protein contact prediction by graph analysis

open access: yesBMC Bioinformatics, 2007
Background Accurate prediction of intra-protein residue contacts from sequence information will allow the prediction of protein structures. Basic predictions of such specific contacts can be further refined by jointly analyzing predicted contacts, and by
Eyal Eran   +3 more
doaj   +1 more source

NodeSim: node similarity based network embedding for diverse link prediction

open access: yesEPJ Data Science, 2022
In real-world complex networks, understanding the dynamics of their evolution has been of great interest to the scientific community. Predicting non-existent but probable links is an essential task of social network analysis as the addition or removal of
Akrati Saxena   +2 more
doaj   +1 more source

Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce   +72 more
wiley   +1 more source

Intra-cluster correlations. [PDF]

open access: yes, 2020
A Intra-cluster correlations of the venous cluster vary between 0.42 and 0.67, all highly significant. B Intra-cluster correlations of the deep gray matter cluster vary between 0.38 and 0.82, all highly significant. Sig.
Philipp Mächler (8727261)   +7 more
core   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi   +8 more
wiley   +1 more source

Fast intra prediction algorithm applied in QS enhancement layer

open access: yesTongxin xuebao, 2011
A fast intra coding algorithm was proposed which was suitable for enhancement layer in quality salability.Base on the coding structure of quality scalability,our algorithm used the relationships between layers,the relationships between rate distortion ...
WANG Da-yong1 SHU Jian2
doaj   +2 more sources

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