Results 221 to 230 of about 308,819 (293)

N4‐acetylcytidine in LncRNA Gm26917 Promotes Translation in Female Germline Stem Cells by Recruiting Ribosomal Protein mRNA via EEF1A1

Advanced Science, EarlyView.
This work establishes that ac4C modification on lncRNA Gm26917 governs its spatial interactions with Rpl10 mRNA, and RBP EEF1A1 mediates the interaction between Gm26917 and Rpl10. It elucidates a novel ac4C‐Gm26917‐EEF1A1‐Rpl10 axis in FGSC maintenance both in vitro and in vivo, and provides a potential molecular target for modulating germ cell ...
Xinyue Li, Xiaopeng Hu, Ji Wu
wiley   +1 more source

Ruptured Ovarian Endometrioma During Pregnancy: A Case Report and Review Highlighting Clinically Occult Risk Factors. [PDF]

Cureus
Miyazaki Y, Takada S, Yamazaki R, Hirabuki S, Sasaki H.   +4 more
europepmc   +1 more source

A Photothermal Transducer Regulates Transmembrane Calcium Flow for Synergistic Osteoarthritis Therapy

Advanced Science, EarlyView.
Upon NIR irradiation at 808 nm, the activity of TRPV4 was inhibited by M2M@BPSC, which led to reduced calcium influx, mitochondrial protection, and, importantly, the transcriptional activation of the STAT6‐EGR2 pathway. The improved macrophage function indirectly readjusts the equilibrium between C‐ECM and F‐ECM to reconstruct a suitable ...
Chenqi Yu, Yang Liu, Kang Kang, Jianfeng Yu, Xiaowei Xia, Yaoge Deng, Yingjie Lu, Huilin Yang, Lisong Li, Wu Xu, Yijian Zhang, Xuesong Zhu   +11 more
wiley   +1 more source

Development and validation of a nomogram for predicting pulmonary embolism recurrence using muscle and fat parameters. [PDF]

Sci Rep
Cao J, Niu S, Li X, Liu H.
europepmc   +1 more source

A NeuroD1 AAV‐Based Gene Therapy for Functional Brain Repair in Alzheimer's Disease‐Like Non‐Human Primate Model

Advanced Science, EarlyView.
This study tests NeuroD1 AAV‐based gene therapy in a non‐human primate Alzheimer's disease model. The therapy prevents neuronal damage, inhibits hippocampal atrophy, and reduces neuroinflammation. It also repairs vascular and blood‐brain barrier damage, restores cerebrospinal fluid biomarkers, enhances hippocampal glucose metabolism, and improves ...
Zhouquan Jiang, Yongpeng Qin, Bin Luo, Fan Bai, Jiangyue Liu, Long Ma, Shu He, Rongjie Chen, Yuchen Wang, Shanggong Liu, Ying Sun, Yi Chen, Shuo Zhang, Jiaqi Liang, Feng Liao, Huiyi Wei, Junjie Wei, Lu Wang, Hao Xu, Zheng Wu, Gong Chen, Wenliang Lei   +21 more
wiley   +1 more source

Application of bedside ultrasound assessment of diaphragmatic function in preparing tracheostomised patients for ventilator liberation and decannulation: a narrative review. [PDF]

J Thorac Dis
Li Y, Wang SS, Li KY, Zhang ZN, Chen YP, Xia JY.   +5 more
europepmc   +1 more source

Influence of scan mode, tilt, and radiation dose on CT radiomic metrics. [PDF]

J Appl Clin Med Phys
Yadav N, Lei X, Cen SY, Levy J, Jensen K, Varghese BA.   +5 more
europepmc   +1 more source

Machine learning-based prediction of hernia risk in peritoneal dialysis patients: a comparative study of models and SHAP-driven interpretability analysis. [PDF]

Front Med (Lausanne)
Cao Y, Hu X, Fang T, Guo J.
europepmc   +1 more source

Artificial intelligence for prostate cancer detection and risk stratification using transrectal ultrasound: a narrative review. [PDF]

Gland Surg
Zhang Q, Zhou C, Chen Y, Luo Y.
europepmc   +1 more source