Results 41 to 50 of about 4,932 (181)

Advancing Treatment of Degenerative Eye Diseases at the Nanoscale

Smart Medicine, Volume 5, Issue 4, August 2026.
Nanotherapeutics possess the potential to overcome longstanding bottlenecks in treating degenerative ophthalmic diseases. With a highly tunable surface chemistry, nanotechnology platforms can be customized to navigate specific anatomical barriers in the eye and target pathways of diseases.
Li Yao Jin, Evashiniee G. P. Selvam, Qinsong Mei, Chi D. Luu, Yeannie H. Y. Yap, Daniel B. L. Teh   +5 more
wiley   +1 more source

Randomized, single‐centre, double‐blinded repeated dose investigation of safety and tolerability of ocular administrations of a novel silica eye drop product in healthy volunteers

Acta Ophthalmologica, Volume 104, Issue 5, Page 572-579, August 2026.
Abstract Purpose Managing ocular diseases often requires frequent eye drop administration, which can challenge patient compliance. A long‐acting eye drop technology using an amorphous synthetic silica composite was developed to address this. Our study aimed to assess the safety and tolerability of the Silica Eye Drop platform in healthy volunteers over
Aleksandra Poluianova, Marceline N. Akieh‐Pirkanniemi, Arto Hartikainen, Hanna Arstila, Kai Kaarniranta, Lasse Leino   +5 more
wiley   +1 more source

Effects of intracameral dexamethasone injection versus topical steroids post phacoemulsification operation

Journal of the Egyptian Ophthalmological Society
Introduction Cataract surgery is one of the most commonly performed surgeries worldwide, with nearly 20 million cases annually. Ophthalmologists usually use a prophylactic perioperative regimen consisting of topical corticosteroids and nonsteroidal anti ...
Alaa I. A. Ghonim, Mervat E. Elgharieb, Amr A.-F. Gab-Alla, Ehab M. Moawad   +3 more
doaj   +1 more source

Management of acute corneal hydrops with intracameral gas injection

American Journal of Ophthalmology Case Reports, 2020
Purpose: To report two cases of severe acute corneal hydrops that were resolved by intracameral gas injection alone. Observations: Case 1 is a 27-year-old woman with bilateral severe keratoconus who developed sequential acute corneal hydrops in the right
Jamasb J. Sayadi, Helene Lam, Charles C. Lin, David Myung   +3 more
doaj   +1 more source

Lessons Learnt From 25 Years of Endophthalmitis: Causes, Microbiology and Visual Outcome Trends

Clinical &Experimental Ophthalmology, Volume 54, Issue 6, Page 812-822, August 2026.
ABSTRACT Background We aimed to study the trends in microbiology, precipitating causes and outcomes of endophthalmitis in Victoria, Australia, over a 25‐year period. To the best of our knowledge, this is the longest study of endophthalmitis in Australia.
Zelia K. Chiu, Rosie C. H. Dawkins, Gursimrat K. Bhullar, Ebrar Al‐Yasery, Penelope J. Allen   +4 more
wiley   +1 more source

Goldmann and error correcting tonometry prisms compared to intracameral pressure

BMC Ophthalmology, 2018
Background Compare Goldmann applanation tonometer (GAT) prism and correcting applanation tonometry surface (CATS) prism to intracameral intraocular pressure (IOP), in vivo and in vitro.
Sean McCafferty, Jason Levine, Jim Schwiegerling, Eniko T. Enikov   +3 more
doaj   +1 more source

A Viscous DES‐AAV‐Foxo1 Delivery System With High Transfection Efficiency for the Treatment of Corneal Endothelial Dysfunction by Restoring Mitochondria‐ER Contacts

Advanced Science, Volume 13, Issue 41, 22 July 2026.
High glucose triggers corneal endothelial dysfunction by impairing FOXO1‐mediated ITPR1 transcription, leading to disrupted mitochondria‐associated membrane (MAM) integrity and defective ER‐to‐mitochondria Ca2+ transfer. This study develops an innovative viscous DES‐AAV‐Foxo1 delivery system with enhanced transfection efficiency. This non‐invasive gene
Hongran Zhao, Xiaoyu Li, Hongwei Wang, Zongyi Li, Qun Wang, Yangyang Zhang, Xu Jing, Xia Qi, Qingjun Zhou, Shengqian Dou, Lixin Xie   +10 more
wiley   +1 more source

Pupil Dilation with Intracameral Epinephrine Hydrochloride during Phacoemulsification and Intraocular Lens Implantation

Journal of Ophthalmology, 2016
Objective. To investigate mydriatic effect of intracamerally injected epinephrine hydrochloride during phacoemulsification and intraocular lens (IOL) implantation. Methods. Eighteen cataract patients for bilateral phacoemulsification were enrolled.
A-Yong Yu, Hua Guo, Qin-Mei Wang, Fang-Jun Bao, Jing-Hai Huang   +4 more
doaj   +1 more source

Two Cases of Fibrin Membrane‐Induced Pupillary Block Treated With Neodymium‐Doped Yttrium Aluminium Garnet (Nd:YAG) Laser After Cataract Surgery in Dogs

Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.
This study evaluates the clinical efficacy of Nd:YAG laser membranotomy in dogs with fibrin membrane‐induced pupillary block (FMPB). Targeted application of the Nd:YAG laser safely disrupts the obstructive pupillary membrane, thereby restoring normal aqueous humour outflow and effectively resolving secondary intraocular pressure (IOP) elevation without
Haerin Yoon, Jiyi Hwang, Ji Seung Jung, Myeon‐Jee Kwon, Jungyeon Yong, Sungin Lee, Kyung‐Mee Park   +6 more
wiley   +1 more source

Travoprost Intracameral Implant Demonstrates Superior IOP Lowering Versus Topical Prostaglandin Analog Monotherapy in Patients with Open-Angle Glaucoma or Ocular Hypertension

Ophthalmology and Therapy
Introduction This study was conducted to analyze and compare the intraocular pressure (IOP) treatment effect of the slow-eluting (SE) travoprost intracameral implant to the IOP treatment effect of topical prostaglandin analog (PGA) monotherapy in a ...
Jason Bacharach, Long V. Doan, Kerry G. Stephens, Dale W. Usner, Angela C. Kothe, L. Jay Katz, Tomas Navratil   +6 more
doaj   +1 more source