Results 241 to 250 of about 3,321,426 (398)

Modular and hierarchical self-assembly of siRNAs into supramolecular nanomaterials for soft and homogeneous siRNA loading and precise and visualized intracellular delivery

, 2022
Xiaowen Guan, Fan-Qi Meng, Hongwei Tan, Xiaoni Wang, Jinɡjinɡ Li, Juanjuan Wei, Jin Ouyang, Na Na   +7 more
openalex   +2 more sources

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Tissue fractionation studies. 6. Intracellular distribution patterns of enzymes in rat-liver tissue.

Biochemical Journal, 1955
B. C. D. Duve, B. C. Pressman, R., Gianetto, R. Wattiaux   +4 more
semanticscholar   +1 more source

Hydrophobic Residues at the Intracellular Domain of the M2 Protein Play an Important Role in Budding and Membrane Integrity of Influenza Virus

, 2022
Danqi Bao, Chenyang Lu, Tianxin Ma, Guanlong Xu, Yaqing Mao, Lingxiang Xin, Shiqi Niu, Zihua Wu, Xuesong Li, Qiaoyang Teng, Zejun Li, Qinfang Liu   +11 more
openalex   +2 more sources

Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte, Lucy Norcliffe‐Kaufmann, Maria Luisa Cotrina, Zenith Khan, Kaia Dalamo, Patricio Millar Vernetti, Matthew Lawless, Elisabetta Morini, Monica Salani, Marla Weetall, Jana Narasimhan, Agostino G. Rocha, Susan A. Slaugenhaupt, Horacio Kaufmann   +13 more
wiley   +1 more source

An exhaustive cell-based screen coupled with an intracellular-induced lux-based reporter identified bioactive molecules that inhibit host cell infection by intracellular pathogens. [PDF]

Front Cell Infect Microbiol
Adani B, Plotnikov A, Lueken L, Shomer I, Shurrush K, Meyer N, Künnemann K, Kellermann M, Margulies D, Grassl GA, Hensel M, Barr HM, Gal-Mor O.   +12 more
europepmc   +1 more source

Intracellular innate immune surveillance devices in plants and animals

Science, 2016
Jonathan D. G. Jones, R. Vance, J. Dangl
semanticscholar   +1 more source

Novel Insights Into Sterol Uptake and Intracellular Cholesterol Trafficking During Eimeria bovis Macromeront Formation

, 2022
Liliana M. R. Silva, Zahady D. Velásquez, Sara López-Osorio, Carlos Hermosilla, Anja Taubert   +4 more
openalex   +1 more source

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin, Liu Dong, Ying Wang, Dingxian He, Chong Yan, Jianying Xi, Haoqin Jiang, Yu Shi, Ming Guan, Chongbo Zhao, Jie Song, Sushan Luo   +11 more
wiley   +1 more source

Nutrition, Cell Signalling, Mitochondrial Function, and Chronic Non-Communicable Disease. [PDF]

Int J Mol Sci
Phillips R.
europepmc   +1 more source