Results 271 to 280 of about 3,321,426 (398)

Sequence Determinants of Intracellular Phase Separation by Complex Coacervation of a Disordered Protein.

Molecules and Cells, 2016
Chi W. Pak, Martyna Kosno, A. Holehouse, S. Padrick, A. Mittal, Rustam Ali, A. Yunus, David R. Liu, R. Pappu, M. Rosen   +9 more
semanticscholar   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao, Rong Li, Yu‐Xiang Jiao, Kai Ma, Hong‐Qi Yang, Zheng‐Yu Sun, Jie‐Wen Zhang, Shuai Chen   +7 more
wiley   +1 more source

Expression of the VapD protein by <i>Helicobacter pylori</i> during intracellular infection. [PDF]

Microbiology (Reading)
Flores-Alanis A, Delgado G, Santiago-Olivares C, Escobar-Sánchez ML, Torres-Ramírez N, Luna-Pineda VM, Cruz-Rangel A, Cortés-Sarabia K, Méndez JL, Espinosa-Camacho F, Cravioto A, Morales-Espinosa R.   +11 more
europepmc   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Large-scale phenotyping and comparative genomics reveal genetic features of Listeria persistence in epithelial cells. [PDF]

PLoS Pathog
Lotoux A, Bertrand M, Douarre PE, Kortebi M, Riveiro H, Palma F, Lakisic G, Fox EM, Guillier L, Oevermann A, Roussel S, Bierne H, Pagliuso A, Milohanic E.   +13 more
europepmc   +1 more source

Alyssin and Iberin in Cruciferous Vegetables Exert Anticancer Activity in HepG2 by Increasing Intracellular Reactive Oxygen Species and Tubulin Depolymerization

, 2019
Piman Pocasap, Natthida Weerapreeyakul, Kanjana Thumanu   +2 more
openalex   +2 more sources

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone, Freddy Chafota, Miguel E. Rentería, Randi J. Hagerman, Ellery Santos, Anna Atkinson, Nicholas G. Martin, Elsdon Storey, Danuta Z. Loesch   +8 more
wiley   +1 more source

Generation of a HiBiT-expressing recombinant rat hepacivirus supporting both in vivo and in vitro infection. [PDF]

PLoS Pathog
Akaike Y, Tanaka T, Kasai H, Yamashita A, Matsuura Y, Moriishi K.   +5 more
europepmc   +1 more source

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich, Jonathan A. Gernert, Hanna Zimmermann, Lisa Tagnin, Marianthi Zeinaki, Laura Sanzo, Letizia Vogler, Elisabeth Kaufmann, Justina Dargvainiene, Frank Leypoldt, Gérard N. Bischof, Robert Perneczky, Boris‐Stephan Rauchmann, Simon Lindner, Günter U. Höglinger, Rudolf A. Werner, Martin Kerschensteiner, Tania Kümpfel, Matthias Brendel, Franziska S. Thaler   +19 more
wiley   +1 more source

Melanin Metabolism: A Novel Oxidative Degradation Mechanism and Regulation by Hydrolyzed Conchiolin Protein. [PDF]

J Cosmet Dermatol
Zhao X, Zeng H, Zhu L, Gu L.
europepmc   +1 more source