Aquaporin-4 and brain edema. [PDF]
Aquaporin-4 (AQP4) is a water-channel protein expressed strongly in the brain, predominantly in astrocyte foot processes at the borders between the brain parenchyma and major fluid compartments, including cerebrospinal fluid (CSF) and blood.
A Lehmenkuhler +38 more
core +2 more sources
Activation of Extracellular-signal Regulated Kinase (ERK1/2) by Fluid Shear is Ca\u3csup\u3e2+\u3c/sup\u3e- and ATP-dependent in MC3T3-E1 Osteoblasts [PDF]
To determine the role of Ca2+ signaling in activation of the Mitogen-Activated Protein Kinase (MAPK) pathway, we subjected MC3T3-E1 pre-osteoblastic cells to inhibitors of Ca2+ signaling during application of fluid shear stress (FSS).
Duncan, Randall L. +7 more
core +1 more source
Acoustically controlled enhancement of molecular sensing to assess oxidative stress in cells [PDF]
We demonstrate a microfluidic platform for the controlled aggregation of colloidal silver nanoparticles using surface acoustic waves (SAWs), enabling surface enhanced Raman scattering (SERS) analysis of a cell based model for oxidative damage.
Auchinvole, C. +4 more
core +1 more source
This study examined the effects of changes in rumen fermentation during the weaning transition on abundance of transporters involved in volatile fatty acid (VFA) absorption or intracellular pH homeostasis. Holstein bull calves (n = 27) were assigned to 1
Rebecca L. Hiltz +4 more
doaj +1 more source
Evaluation of iron, electrolytes (sodium, potassium, and chloride) levels in human males suffering from low testosterone [PDF]
Spermatogenesis, male sex characteristics, sex differentiation, and fertility are all regulated by testosterone, the primary hormone in males. Many organ systems are affected by low testosterone in men.
Mohammed Hasan Barrak +2 more
doaj +1 more source
This study was designed to identify the fluid spaces that are most changed during ultrafiltration (UF) according to intradialytic blood pressure (BP) difference. BP data were collected five times (before hemodialysis [HD] and 1–4 h of HD).
Young Eun Kwon +2 more
doaj +1 more source
Intracellular mechanochemical waves in an active poroelastic model [PDF]
Many processes in living cells are controlled by biochemical substances regulating active stresses. The cytoplasm is an active material with both viscoelastic and liquid properties. We incorporate the active stress into a two-phase model of the cytoplasm
Alonso Muñoz, Sergio +3 more
core +2 more sources
A C3(H20) recycling pathway is a component of the intracellular complement system [PDF]
An intracellular complement system (ICS) has recently been described in immune and nonimmune human cells. This system can be activated in a convertase-independent manner from intracellular stores of the complement component C3. The source of these stores
Botto +11 more
core +2 more sources
Intracellular and extracellular penetration of azithromycin into inflammatory and noninflammatory blister fluid [PDF]
The penetration of azithromycin into the blister fluids of six volunteers was analyzed after a 5-day regimen (total of 1.5 g). Differences in drug concentrations in a paper disk and serum and in the mass of azithromycin from inflammatory blister chamber leukocytes and noninflammatory blister chamber leukocytes were significant (P < 0.05).
C D, Freeman +5 more
openaire +3 more sources
Disregarded effect of biological fluids in siRNA delivery : human ascites fluid severely restricts cellular uptake of nanoparticles [PDF]
Small interfering RNA (siRNA) offers a great potential for the treatment of various diseases and disorders. Nevertheless, inefficient in vivo siRNA delivery hampers its translation into the clinic.
Braeckmans, Kevin +5 more
core +2 more sources

