Results 191 to 200 of about 184,061 (226)

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

Advanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey, Sudhir Kumar Rai, Li Ma, Lauren Higa, Vedbar Khadka, Hua Yang, Youping Deng   +6 more
wiley   +1 more source

Extracellular Matrix-Derived Matrikines: Circulating Peptides as Candidate Mediators of Lung-to-Brain Signaling. [PDF]

Int J Mol Sci
Klegeris A.
europepmc   +1 more source

A Dual‐Responsive Versatile Nanohybrid Orchestrating Tumor Elimination and Tumor‐Associated Osteolysis Restoration via Sequential Release

Advanced Science, EarlyView.
The versatile CaO2@CuMOF@HAP nanohybrid demonstrates an outstanding MMP9/pH‐triggered release performance for sequential release of osteogenic growth peptide into deep‐seated tumor‐infiltrated bone destruction areas and dual ions into tumor cells, enabling efficient tumor‐associated osteolysis restoration and tumor elimination for more comprehensive ...
Lan Liu, Han‐Zhe Liu, Zhe‐Nan Liu, Tong Wang, Li‐Li Yu, Qiu‐Jing Li, Zi‐Yi Chen, Guo‐Feng Luo, Zheng‐Jun Shang   +8 more
wiley   +1 more source

Liquid-liquid phase separation in cancer therapy resistance. [PDF]

iScience
Hu P, Ding H, Yue N, Ye J, Ruan S, Qian Y, Wang C, Song D.   +7 more
europepmc   +1 more source

Sex‐Specific Regulation of Glycemic Homeostasis by Theabrownin from Pu‐erh Tea

Advanced Science, EarlyView.
Pu‐erh tea's key component, theabrownin (TB), lowers blood glucose in a sex‐specific manner. In females, estrogen boosts intestinal MUC2 production, which dramatically enhances TB's ability to inhibit the carbohydrate‐digesting enzyme α‐glucosidase.
Yang Li, Junliang Kuang, Dan Zheng, Jieyi Wang, Kun Ge, Chun Qu, Xiaojiao Zheng, Zhenxing Ren, Fengjie Huang, Mingliang Zhao, Yimin Sun, Huiheng Zhang, Keke Ding, Xixi Xia, Yajun Tang, Lu Liu, Jian Zhou, Fei Gao, Xiaohui Ma, Yongquan Xu, Guoxiang Xie, Aihua Zhao, Wei Jia   +22 more
wiley   +1 more source

ULK1-driven autophagy modulation alters tumor-promoting pathways in triple-negative breast cancer. [PDF]

Med Oncol
Bal Albayrak MG, Yanar S, Korak T, Akpinar G, Kasap M.   +4 more
europepmc   +1 more source

Galanin Receptors in the Central Nervous System: Exploring Ligand Interactions, Signal Transduction, and Potential Clinical Implications. [PDF]

Molecules
Owczarek A, Blecharz-Klin K.
europepmc   +1 more source

The Matrisome as an Immunomodulator: A Role Far Beyond Its Structural Support. [PDF]

Biomolecules
Quan T.
europepmc   +1 more source

Identifying a Novel BCL2L1-Targeting Peptide from Porcine Placenta for Lymphoma Therapy. [PDF]

ACS Omega
Ongtanasup T, Suwannakul N, Eawsakul K.
europepmc   +1 more source

Functions and mechanisms of circular RNAs in cancer stem cells and therapy resistance. [PDF]

Front Cell Dev Biol
Yuan Y, Zhang D, Wang J, Jiang X, Duan L.   +4 more
europepmc   +1 more source