Results 1 to 10 of about 504,038 (175)

The role and mechanism of ARRB1 in simulated space radiation and microgravity-induced lung carcinogenesis [PDF]

open access: yesnpj Microgravity
Microgravity can exacerbate radiation-induced DNA damage response, suggesting that microgravity may increase the risk of tumor initiation and development. However, the specific mechanism is still unclear.
Ying Xu   +8 more
doaj   +2 more sources

CalQuo 2 : Automated Fourier-space, population-level quantification of global intracellular calcium responses [PDF]

open access: yesScientific Reports, 2017
Intracellular calcium acts as a secondary messenger in a wide variety of crucial biological signaling processes. Advances in fluorescence microscopy and calcium sensitive dyes has led to the routine quantification of calcium responses in non-excitable ...
Angela M. Lee   +2 more
doaj   +3 more sources

THE REACTION OF PHOSPHORUS-CONTAINING INTRACELLULAR INCLUSIONS TO SPACE WEATHER CHANGES

open access: yesOdessa Astronomical Publications, 2016
It is known that the bio-astronomical effect of Chizhevsky-Velhover is based on the cytochemical metachromatic reaction of polyphosphatecontaining volutin granules of microorganisms.
E. N. Gromozova   +3 more
doaj   +3 more sources

Spatial chaos and complexity in the intracellular space of cancer and normal cells. [PDF]

open access: yesTheor Biol Med Model, 2013
One of the most challenging problems in biological image analysis is the quantification of the dynamical mechanism and complexity of the intracellular space. This paper investigates potential spatial chaos and complex behavior of the intracellular space of typical cancer and normal cell images whose structural details are revealed by the combination of
Pham TD, Ichikawa K.
europepmc   +4 more sources

Protein aggregation drives cell aging in a size-specific manner in Escherichia coli [PDF]

open access: yesmBio
Aging, the decline in physiological function over time, is marked by the intracellular accumulation of damaged components. It can be attributed to trade-offs between organismal maintenance and the generation of high-quality offspring, where the parent ...
Linda Wagener   +5 more
doaj   +2 more sources

Quest for space: Tenacity of DNA, Protein, and Lipid macromolecules in intracellular crowded environment

open access: yesBiomolecular Concepts
The biochemical processes in the cellular milieu involving biomacromolecular interaction usually occur in crowded and heterogeneous environments, impacting their structure, stability, and reactivity.
Phogat Priyanka   +5 more
doaj   +3 more sources

A Higher Angiogenin Expression is Associated With a Nonnuclear Maspin Location in Laryngeal Carcinoma [PDF]

open access: yesClinical and Experimental Otorhinolaryngology, 2015
ObjectivesIn numerous malignancies, angiogenin (ANG) and Maspin are important proangiogenic and antiangiogenic regulators, respectively. The aim of this study was to identify potential relationships between the biological roles of these two proteins in ...
Andrea Lovato   +7 more
doaj   +1 more source

Segmentation of mitochondria in intracellular space [PDF]

open access: yes2013 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology (CIBCB), 2013
Information of cellular organelle location and morphology is essential for cancer simulation. In order to obtain such information, the segmentation of the organelles from electronic microscopy intracellular image is crucial. In this paper, we focus on the segmentation of mitochondria organelle which is one of the most important organelles tightly ...
Nhan Nguyen-Thanh   +2 more
openaire   +1 more source

Intracellular mechanisms of fungal space searching in microenvironments [PDF]

open access: yesProceedings of the National Academy of Sciences, 2018
AbstractThe underlying intracellular mechanisms involved in the fungal growth received considerable attention, but the experimental and theoretical work did not take into account the modulation of these processes by constraining microenvironments similar to many natural fungal habitats.
Marie Held   +3 more
openaire   +3 more sources

Building Accurate Intracellular Polarity Maps through Multiparametric Microscopy

open access: yesMethods and Protocols, 2020
The precise knowledge of intracellular polarity, a physiological parameter that involves complex and intertwined intracellular mechanisms, may be relevant in the study of important diseases like cancer or Alzheimer’s.
M. Carmen Gonzalez-Garcia   +3 more
doaj   +1 more source

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