A stochastic model for intracellular active transport
Biomath, 2018 We develop a stochastic model for an intracellular active transport problem. Our aims are to calculate the probability that a molecular motor reaches a hidden target, to study what influences this probability and to calculate the time required for the ...
Raluca Purnichescu Purtan +1 more
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The determination of intracellular water space by NMR
FEBS Letters, 1985 A new method for the determination of intracellular water space using NMR spectroscopy is described. The method is based on the measurement of 59Co NMR signal intensity of an inert, stable and membraneimpermeable cobalt(III) compound such as Co(CN)6 3− or Co(imidazole)6 3+ and the 2H or 1H NMR signal intensities of the freely permeable water.
Shinar, Hadassah, Navon, Gil
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Epoxysuccinyl peptide-derived cathepsin B inhibitors: Modulating membrane permeability by conjugation with the C-terminal heptapeptide segment of penetratin [PDF]
, 2002 Besides its physiological role in lysosomal protein breakdown, extralysosomal cathepsin B has recently been implicated in apoptotic cell death. Highly specific irreversible cathepsin B inhibitors that are readily cellpermeant should be useful tools to ...
Assfalg-Machleidt, Irmgard +5 more
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Orthophosphate Turnover in the Extracellular and Intracellular Space of Mouse Liver [PDF]
European Journal of Biochemistry, 1969 The flux rates of Pi from blood plasma into the extracellular and intracellular space of mouse liver have been measured in vivo with the [32P]Pi-tracer technique. The specific radioactivities of plasma Pi and total liver Pi have been measured 0.1–4 min after injection of carrier-free [32P]Pi.
U, Till, D, Brox, H, Frunder
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Intracellular Toxic AGEs (TAGE) Triggers Numerous Types of Cell Damage
Biomolecules, 2021 The habitual intake of large amounts of sugar, which has been implicated in the onset/progression of lifestyle-related diseases (LSRD), induces the excessive production of glyceraldehyde (GA), an intermediate of sugar metabolism, in neuronal cells ...
Masayoshi Takeuchi +9 more
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Nitric oxide synthase blockade and body fluid volumes
Brazilian Journal of Medical and Biological Research, 2002 The influence of chronic nitric oxide synthase inhibition with N G-nitro-L-arginine methyl ester (L-NAME) on body fluid distribution was studied in male Wistar rats weighing 260-340 g.
A.M. Balaszczuk +4 more
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Effect of macromolecular crowding on the kinetics of glycolytic enzymes and the behaviour of glycolysis in yeast [PDF]
, 2018 Water is involved in all aspects of biological activity, both as a solvent and as a reactant. It is hypothesized that intracellular water is in a highly structured state due to the high concentrations of macromolecules in the cell and that this may ...
Bagatolli, Luis Alberto +2 more
core +3 more sources
Impact of limited solvent capacity on metabolic rate, enzyme activities, and metabolite concentrations of S. cerevisiae glycolysis [PDF]
, 2008 The cell's cytoplasm is crowded by its various molecular components, resulting in a limited solvent capacity for the allocation of new proteins, thus constraining various cellular processes such as metabolism.
Barabási, AL +3 more
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Signalling in space and time: systems dynamics of intracellular communication [PDF]
EMBO reports, 2011 The EMBO Spatial meeting took place in May 2011 in Switzerland. It promoted interactions between cell biologists, neuroscientists, system biologists and mathematicians, all united by a common interest in understanding how cells integrate signals in space and time.
Shelly Tzlil, Rejji Kuruvilla
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Nature Communications, 2022 “Intracellular phase separation is emerging as a universal principle for organizing biochemical reactions in time and space. Here the authors show that PopZ condensate dynamics support cell division and using PopZ modular architecture, the tunable PopTag
Keren Lasker +12 more
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