Results 81 to 90 of about 504,058 (195)

Hijacking host cell highways: manipulation of the host actin cytoskeleton by obligate intracellular bacterial pathogens

open access: yesFrontiers in Cellular and Infection Microbiology, 2016
Intracellular bacterial pathogens replicate within eukaryotic cells and display unique adaptations that support key infection events including invasion, replication, immune evasion, and dissemination.
Punsiri M Colonne   +2 more
doaj   +1 more source

Comprehensive Roles of ZIP and ZnT Zinc Transporters in Metabolic Inflammation

open access: yesTargets
Zinc homeostasis is fundamental to metabolic health, orchestrated by the coordinated actions of two major zinc transporter families: ZIP (Zrt- and Irt-like proteins) and ZnT (zinc transporters).
Susmita Barman   +2 more
doaj   +1 more source

Comparative ribosome profiling uncovers a dominant role for translational control in Toxoplasma gondii

open access: yesBMC Genomics, 2017
Background The lytic cycle of the protozoan parasite Toxoplasma gondii, which involves a brief sojourn in the extracellular space, is characterized by defined transcriptional profiles.
Musa A. Hassan   +4 more
doaj   +1 more source

Transcending membrane barriers: advances in membrane engineering to enhance the production capacity of microbial cell factories

open access: yesMicrobial Cell Factories
Microbial cell factories serve as pivotal platforms for the production of high-value natural products, which tend to accumulate on the cell membrane due to their hydrophobic properties.
Tao Wu   +4 more
doaj   +1 more source

The Behaviour of Intracellular Water in Yeast Cells Affected by Organic Solvents

open access: yesХімія, фізика та технологія поверхні, 2012
Yeast Saccharomyces cerevisiae cells dry (containing approximately 7 wt.% of water) and partially rehydrated (10 wt.% addition of water) and with added organic solvents (10 wt.% or 2–3 g per gram of dry cells) nonpolar (C6H6, CCl4) or polar (CD3CN, (CH3 ...
V. M. Gun'ko   +3 more
doaj  

Expanding the payload scope in antibody-drug conjugates by delivery of hydroxy-containing drugs through self-immolative phosphoramidates

open access: yesNature Communications
Despite recent advances in targeted drug delivery, approved Antibody-Drug-Conjugates (ADCs) are still limited by the delivery of a restricted set of payloads with limited modes of action (MOA). Versatile linkers, applicable to functional groups prevalent
Philipp Ochtrop   +20 more
doaj   +1 more source

Intracellular Distribution of Lipids and Encapsulated Model Drugs from Cationic Liposomes with Different Uptake Pathways

open access: yesInternational Journal of Nanomedicine, 2020
Masato Takikawa,1 Mizuki Fujisawa,2 Kazuma Yoshino,2 Shinji Takeoka2,3 1Department of Advanced Science and Engineering, Graduate School of Advanced Science and Engineering, Waseda University, Tokyo 169-8555, Japan; 2Department of Life Science and Medical
Takikawa M   +3 more
doaj  

Aß degradation--the inside story

open access: yesFrontiers in Aging Neuroscience, 2014
Malcolm A Leissring
doaj   +1 more source

Dissecting the Simultaneous Extracellular/Intracellular Contributions to Cr(VI) Reduction under Aerobic and Anaerobic Conditions Using the Newly Isolating Cr(VI)-Reducing Bacterium of Pseudomonas sp. HGB10

open access: yesMicroorganisms
Quantifying extracellular and intracellular contributions to Cr(VI) reduction is crucial for understanding bacterial Cr(VI)-reduction mechanisms. However, this contribution under different oxygen conditions remains largely unexplored.
Shenglei Chen   +4 more
doaj   +1 more source

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