Results 181 to 190 of about 67,933 (309)

APOE and Cerebral Microbleeds: Insights Into Causal Proteins and Therapeutic Targets

open access: yesBrain and Behavior, Volume 16, Issue 6, June 2026.
This study identifies APOE as a key causal protein for cerebral microbleeds (CMBs). By integrating Mendelian randomization (MR) and colocalization analysis of the plasma proteome from UKB‐PPP and deCODE datasets, we provide genetic evidence that circulating APOE levels are causally linked to CMB susceptibility. Furthermore, protein–protein interaction (
Lei Yang   +8 more
wiley   +1 more source

Intracerebral hemorrhage and carotid-cavernous fistulas: a rare connection. [PDF]

open access: yesNeuroradiology
Gronemann C   +4 more
europepmc   +1 more source

Prevalence and Risk Factors for Cerebral Microbleeds in Chinese Patients With Acute Ischemic Stroke

open access: yesBrain and Behavior, Volume 16, Issue 6, June 2026.
Approximately half of the patients with AIS exhibited CMBs, particularly those classified under LAA and SVD subtypes. Hypertension and severe WMH were independently associated with CMB presence. Distinct clinical profiles were observed based on CMB burden and location.
Ruiming Zhu   +5 more
wiley   +1 more source

Decoding spontaneous intracerebral hemorrhage: mechanistic breakthroughs and disruptive revolution in pharmacological treatment. [PDF]

open access: yesExp Mol Med
Chen Y   +14 more
europepmc   +1 more source

Efficacy and Safety of Tirofiban for the Management of Acute Ischemic Stroke: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials (RCTs)

open access: yesBrain and Behavior, Volume 16, Issue 6, June 2026.
Graphical representation of the comparative efficacy and safety of intravenous tirofiban for acute ischemic stroke in randomized controlled trials. ABSTRACT Background: Tirofiban is a GP IIb/IIIa inhibitor, an anti‐platelet drug that is used in ischemic stroke or acute coronary syndromes.
Dorothy Lim Bullecer   +12 more
wiley   +1 more source

Neuroendoscopy Versus External Ventricular Drainage for Thalamic Hemorrhagic Stroke: A Systematic Review and Bayesian Meta‐Analysis

open access: yesBrain and Behavior, Volume 16, Issue 6, June 2026.
ABSTRACT Background Neuroendoscopy and external ventricular drainage are commonly considered first‐line options for managing thalamic hemorrhage. However, their effectiveness in reducing the risk of rebleeding remains unclear. Aim To compare the efficacy and safety of neuroendoscopy versus external ventricular drainage through a systematic review and ...
Pedro Tchicama Sikembi   +5 more
wiley   +1 more source

Where Evidence‐Based Medicine Meets AI: Promise, Pitfalls, and Practice

open access: yes
AEM Education and Training, Volume 10, Issue 3, June 2026.
Sangil Lee   +8 more
wiley   +1 more source

ETV4 Improves Cerebral Ischemia‐Reperfusion Injury by Restraining YBX1‐GPX4‐Ferroptosis Cascades

open access: yesBrain and Behavior, Volume 16, Issue 6, June 2026.
ABSTRACT Background Cerebral ischemia‐reperfusion injury (CIRI) is a critical pathological process following ischemic stroke, with ferroptosis being increasingly recognized as a key contributor to neuronal damage. However, the regulatory mechanisms, particularly the role of specific transcription factors like E26 transformation‐specific variant 4 (ETV4)
Qian Xu, Faming Deng, Dan Yu
wiley   +1 more source

Intracerebral hemorrhage in hemophilia

open access: yesThe Journal of the American Osteopathic Association, 1984
openaire   +2 more sources

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