Results 141 to 150 of about 847,907 (389)

The DEC2‐SCN2A Axis is Essential for the Anticonvulsant Effects of Cannabidiol by Modulating Neuronal Plasticity

open access: yesAdvanced Science, EarlyView.
This study identifies DEC2 as a critical transcriptional repressor of Scn2a that directly binds E‐box motifs in its promoter to regulate neuronal plasticity and epileptogenesis. Functional manipulation of DEC2 alters seizure susceptibility in vivo. Cannabidiol enhances this repression, unveiling a novel DEC2‐SCN2A axis underlying its anticonvulsant ...
Huifang Song   +24 more
wiley   +1 more source

Topiramate is more effective than acetazolamide at lowering intracranial pressure

open access: yesCephalalgia, 2018
Background The management of idiopathic intracranial hypertension focuses on reducing intracranial pressure to preserve vision and reduce headaches.
W. Scotton   +7 more
semanticscholar   +1 more source

Dual‐Energy CT‐Based Assessment of Thrombotic Heterogeneity for Predicting Stroke Source and Response to Machine Thrombectomy: A Step Toward Visualization Thrombus Treatment

open access: yesAdvanced Science, EarlyView.
The research indicates that dual energy CT scanning can accurately predict the stroke source and clinical outcomes by analyzing thrombus heterogeneity. Based on histopathological analysis of thrombus components, these scans are better able to display thrombus details than standard CT scans, which is helpful for the development of visual navigation ...
Jingxuan Jiang   +15 more
wiley   +1 more source

Complications of invasive intracranial pressure monitoring devices in neurocritical care.

open access: yesNeurosurgical Focus, 2017
Intracranial pressure monitoring devices have become the standard of care for the management of patients with pathologies associated with intracranial hypertension.
Samon G Tavakoli   +4 more
semanticscholar   +1 more source

Feasibility of simultaneous intracranial EEG-fMRI in humans: a safety study [PDF]

open access: yes, 2010
In epilepsy patients who have electrodes implanted in their brains as part of their pre-surgical assessment, simultaneous intracranial EEG and fMRI (icEEG-fMRI) may provide important localising information and improve understanding of the underlying ...
Allen, P.J.   +7 more
core  

Advanced Pharmaceutical Nanotechnologies Applied for Chinese Herbal Medicines

open access: yesAdvanced Science, EarlyView.
This review offers a comprehensive overview of pharmaceutical nanotechnology strategies to address limitations associated with the complex material basis and relative mild therapeutic efficacy of Chinese herbal medicines, and summarizes the advantages of these strategies.
Jiameng Li   +11 more
wiley   +1 more source

Extrusion of Intracranial Tumor Mass—A Rare Phenomenon

open access: yesMAMC Journal of Medical Sciences, 2018
Introduction: The extrusion of intramedullary spinal cord tumor is a well known fact. Charles Elsberg described a two-staged approach for the removal of these tumors.
Charandeep S Gandhoke   +4 more
doaj   +1 more source

Blood-based bioenergetic profiling is related to differences in brain morphology in African Americans with Type 2 diabetes. [PDF]

open access: yes, 2018
Blood-based bioenergetic profiling has promising applications as a minimally invasive biomarker of systemic bioenergetic capacity. In the present study, we examined peripheral blood mononuclear cell (PBMC) mitochondrial function and brain morphology in a
Freedman, Barry I   +6 more
core  

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