Results 181 to 190 of about 462,338 (258)

Early Endoscopic Repair of Traumatic Skull Base Dural Injuries: Challenging the Dogma of Conservative Management

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Introduction Traditional management of traumatic skull base dural injury has often favored observation and conservative therapy, despite the risk of delayed intracranial complications. This paradigm originated when operative intervention required craniotomy and carried significant morbidity.
Jessica W. Grayson, Madeline P. Bald, Lauren McLeod, Adam J. Skelton, Nicolaus D. Knight, Do‐Yeon Cho, Justin Turner, Hari Jeyarajan, Kristen O. Riley, Bradford A. Woodworth   +9 more
wiley   +1 more source

The diagnostic value of the circadian rhythm gene KLF10 in anxiety‐depressive disorders and its neuroimmune regulatory mechanisms

Animal Models and Experimental Medicine, EarlyView.
This graphical abstract illustrates the protective role and molecular mechanism of the circadian rhythm‐related gene KLF10, identified as a diagnostic biomarker and therapeutic target in anxiety‐depressive disorder. Model establishment and phenotypes: An anxiety‐depression model was successfully established by chronic restraint stress combined with ...
Anlan Liu, Weifeng Guo, Jianxiang Li, Tiange Zhang, Dan Xu   +4 more
wiley   +1 more source

Thalamic Tuberculoma Presenting as Isolated Gait Disturbance Without Systemic or Meningeal Symptoms in a 2-Year-Old Child: A Case Report. [PDF]

Int Med Case Rep J
Yasmin K, Abdullah M, Shaik S, Zaheer M, Ihtasham A, Siddiqui HH, Shamim S, Hassan Salad H.   +7 more
europepmc   +1 more source

Animal stroke models and outcome evaluation: A review

Animal Models and Experimental Medicine, EarlyView.
Rodents are the preeminent stroke model species. Large animal models exist too, but are poorly standardized. Ischemic and hemorrhagic experimental models are available, with the intraluminal filament model being predominant. Outcomes are evaluated via quantifying subjects' sensorimotor impairment, cognitive memory faculties, degree of cellular ...
Solsa Cariba, Helen M. Atkinson, Anthony K. C. Chan   +2 more
wiley   +1 more source

Intracranial Nocardiosis: A Review of 21 Cases

Indian Journal of Radiology and Imaging
Harshad Arvind Vanjare, Paul Deepak, Bernice T. Selvi, Pavithra Mannam, Abi Manesh, Angel Miraclin, Tony Varghese Panicker, Geeta Chacko, Anitha Jasper   +8 more
doaj   +1 more source

Association of long-term alcohol consumption with DSA-defined concurrent intracranial and extracranial steno-occlusive involvement in acute ischemic stroke. [PDF]

Front Neurol
Jiang L, Wu W, Kong L, Xiong J, Zhang X, Wang W, Guo X.   +6 more
europepmc   +1 more source

Blood Biomarkers of Alzheimer's Disease and Patterns of Structural Brain Changes in the Community

Annals of Neurology, EarlyView.
Objective We aimed to investigate the associations between Alzheimer's disease (AD)‐related blood biomarkers and changes in brain volumes and cerebrovascular burden in community‐dwelling older adults. Methods We included 361 dementia‐free participants with a Mini‐Mental State Examination (MMSE) score ≥ 27 and without prior cerebrovascular events from a
Martina Valletta, Davide Liborio Vetrano, Erika J. Laukka, Grégoria Kalpouzos, Javier Oltra, Debora Rizzuto, Marco Canevelli, Claudia Fredolini, Chengxuan Qiu, Bengt Winblad, Laura Fratiglioni, Giulia Grande   +11 more
wiley   +1 more source

Predictive models for the occurrence of expansive intracranial hematomas and outcomes after surgical evacuation in patients with traumatic brain injury in Uganda: a prospective cohort study. [PDF]

Front Surg
Kamabu LK, Bbosa GS, Oboth R, John Baptist S, Kaddumukasa MN, Deng D, Lekuya HM, Kataka LM, Kiryabwire J, Galukande M, Sajatovic M, Kaddumukasa M, Fuller AT, Haglund MM.   +13 more
europepmc   +1 more source

Cognitive Impairment, Depression and Cerebral Microbleeds in Immune Thrombocytopenia (ITP)

American Journal of Hematology, EarlyView.
Camelia Vladescu, Rozanna Meijboom, Alice C. J. Hart, Deena Paul, Christine Ademokun, Ariam Teklemichael, Bridget Chivers, Anastasia Gontsarova, Richard Szydlo, Adam D. Waldman, Nichola Cooper   +10 more
wiley   +1 more source

Neurotransmitter‐Defined Degeneration Patterns in Sporadic and C9orf72‐Associated Amyotrophic Lateral Sclerosis: Predilection to GABAergic, Serotonergic, Opioid, Glutamatergic, Endocannabinoid, and Microglial Systems—Implications for Therapy Development

Annals of Neurology, EarlyView.
Objective Amyotrophic lateral sclerosis (ALS) has a markedly distinctive clinical and neuroradiological signature, with the preferential involvement of specific brain networks and the apparent sparing of others. The molecular underpinnings of the strikingly selective anatomical vulnerability have not been fully elucidated to date despite the potential ...
Marlene Tahedl, We Fong Siah, Jasmin Lope, Jennifer C. Hengeveld, Mark A. Doherty, Russell L. McLaughlin, Orla Hardiman, Ee Ling Tan, Alison Toomey, Jana Kleinerova, Peter Bede   +10 more
wiley   +1 more source