Results 11 to 20 of about 653,899 (348)

The effect of GLP-1RA exenatide on idiopathic intracranial hypertension: a randomized clinical trial

Brain : a journal of neurology, 2023
Therapeutics to reduce intracranial pressure are an unmet need. Preclinical data have demonstrated a novel strategy to lower intracranial pressure using glucagon-like peptide-1 (GLP-1) receptor signalling.
J. Mitchell, H. Lyons, Jessica Katie Walker, A. Yiangou, O. Grech, Z. Alimajstorovic, N. Greig, Yazhou Li, G. Tsermoulas, K. Brock, S. Mollan, A. Sinclair   +11 more
semanticscholar   +1 more source

Clinical Presentation, Investigation Findings, and Treatment Outcomes of Spontaneous Intracranial Hypotension Syndrome

JAMA Neurology, 2021
This systematic review and meta-analysis provides an objective summary of the available evidence on the clinical presentation, investigations findings, and treatment outcomes for spontaneous intracranial hypotension.
L. D’Antona, Melida Andrea Jaime Merchan, Anna Vassiliou, L. Watkins, I. Davagnanam, A. Toma, M. Matharu   +6 more
semanticscholar   +1 more source

Effectiveness of Bariatric Surgery vs Community Weight Management Intervention for the Treatment of Idiopathic Intracranial Hypertension

JAMA Neurology, 2021
Key Points Question Is bariatric surgery superior to a community weight management intervention in sustaining the weight loss necessary to achieve sustained remission among patients with idiopathic intracranial hypertension?
S. Mollan, J. Mitchell, R. Ottridge, Magda Aguiar, A. Yiangou, Z. Alimajstorovic, D. Cartwright, O. Grech, G. Lavery, C. Westgate, V. Vijay, W. Scotton, B. Wakerley, T. Matthews, A. Ansons, S. Hickman, J. Benzimra, C. Rick, R. Singhal, A. Tahrani, K. Brock, E. Frew, A. Sinclair   +22 more
semanticscholar   +1 more source

Intracranial Efficacy and Survival With Tucatinib Plus Trastuzumab and Capecitabine for Previously Treated HER2-Positive Breast Cancer With Brain Metastases in the HER2CLIMB Trial

Journal of Clinical Oncology, 2020
PURPOSE In the HER2CLIMB study, patients with human epidermal growth factor receptor 2 (HER2)–positive breast cancer with brain metastases (BMs) showed statistically significant improvement in progression-free survival (PFS) with tucatinib.
N. Lin, V. Borges, C. Anders, R. Murthy, E. Paplomata, E. Hamilton, S. Hurvitz, S. Loi, A. Okines, V. Abramson, Philippe Bédard, Mafalda Oliveira, V. Mueller, A. Zelnak, M. DiGiovanna, T. Bachelot, A. J. Chien, R. O'Regan, A. Wardley, A. Conlin, D. Cameron, L. Carey, G. Curigliano, K. Gelmon, S. Loibl, J. Mayor, S. McGoldrick, Xuebei An, E. Winer   +28 more
semanticscholar   +1 more source

Intracranial Efficacy of Selpercatinib in RET Fusion-Positive Non–Small Cell Lung Cancers on the LIBRETTO-001 Trial

Clinical Cancer Research, 2021
Purpose: We report the intracranial efficacy of selpercatinib, a highly potent and selective RET inhibitor, approved in the United States for RET fusion-positive non–small cell lung cancers (NSCLC).
V. Subbiah, J. Gainor, G. Oxnard, D. Tan, D. Owen, B. Cho, H. Loong, C. McCoach, J. Weiss, Y. J. Kim, L. Bazhenova, Keunchil Park, H. Daga, B. Besse, O. Gautschi, C. Rolfo, E. Zhu, J. Kherani, Xin Huang, Suhyun Kang, A. Drilon   +20 more
semanticscholar   +1 more source

Central nervous system teratomas in infants: A report of two cases

Indian Journal of Pathology and Microbiology, 2015
Intracranial teratomas are uncommon neoplasms with most of them being encountered in the pediatric age group. Teratomas are composed of derivatives of all the three germ cell layers and are classified into mature, immature and teratoma with malignant ...
Shatavisha DasGupta, Sanghamitra Mukherjee, Ram Narayan Das, Anway Sen, Uttara Chatterjee, Chhanda Datta, Sandip Chatterjee   +6 more
doaj   +1 more source

Intracranial Arteriovenous Malformation Combined with Multiple Aneurysms Diagnosed by CTA: A Case Report

Journal of the Belgian Society of Radiology, 2023
Arteriovenous malformation (AVM) combined with aneurysms is not uncommon, but AVM of the basilar artery, brainstem, and right middle cerebral artery combined with multiple intracranial aneurysms (IAs) is rare.
Qin Zhang, Yongzhe Hou, Qiong Wang, Xilong Chen   +3 more
doaj   +1 more source

Multimodal non-invasive assessment of intracranial hypertension: an observational study

Critical Care, 2020
Background Although placement of an intra-cerebral catheter remains the gold standard method for measuring intracranial pressure (ICP), several non-invasive techniques can provide useful estimates.
C. Robba, S. Pozzebon, Bedrana Moro, J. Vincent, J. Creteur, F. Taccone   +5 more
semanticscholar   +1 more source

Idiopathic intracranial hypertension: consensus guidelines on management

Journal of Neurology Neurosurgery & Psychiatry, 2018
The aim was to capture interdisciplinary expertise from a large group of clinicians, reflecting practice from across the UK and further, to inform subsequent development of a national consensus guidance for optimal management of idiopathic intracranial ...
S. Mollan, B. Davies, N. Silver, S. Shaw, C. Mallucci, B. Wakerley, A. Krishnan, S. Chavda, S. Ramalingam, J. Edwards, K. Hemmings, M. Williamson, M. Burdon, G. Hassan-Smith, K. Digre, Grant T. Liu, R. Jensen, A. Sinclair   +17 more
semanticscholar   +1 more source

Intracranial Germinoma [PDF]

Baylor University Medical Center Proceedings, 2015
Pineal region tumors make up less than 1% of all intracranial neoplasms, with the majority being of germ cell origin. We describe the diagnostic evaluation and treatment of a patient presenting with neurological deficits who was found to have a germinoma of the pineal gland.
Manoj P, Reddy, Amin F, Saad, Kyle E, Doughty, Danielle, Armstrong, Isaac, Melguizo-Gavilanes, Brennen S, Cheek, Michael J, Opatowsky   +6 more
openaire   +2 more sources