Results 11 to 20 of about 606,004 (349)

The effect of GLP-1RA exenatide on idiopathic intracranial hypertension: a randomized clinical trial

Brain : a journal of neurology, 2023
Therapeutics to reduce intracranial pressure are an unmet need. Preclinical data have demonstrated a novel strategy to lower intracranial pressure using glucagon-like peptide-1 (GLP-1) receptor signalling.
J. Mitchell, H. Lyons, Jessica Katie Walker, A. Yiangou, O. Grech, Z. Alimajstorovic, N. Greig, Yazhou Li, G. Tsermoulas, K. Brock, S. Mollan, A. Sinclair   +11 more
semanticscholar   +1 more source

Clinical Presentation, Investigation Findings, and Treatment Outcomes of Spontaneous Intracranial Hypotension Syndrome

JAMA Neurology, 2021
This systematic review and meta-analysis provides an objective summary of the available evidence on the clinical presentation, investigations findings, and treatment outcomes for spontaneous intracranial hypotension.
L. D’Antona, Melida Andrea Jaime Merchan, Anna Vassiliou, L. Watkins, I. Davagnanam, A. Toma, M. Matharu   +6 more
semanticscholar   +1 more source

Effectiveness of Bariatric Surgery vs Community Weight Management Intervention for the Treatment of Idiopathic Intracranial Hypertension

JAMA Neurology, 2021
Key Points Question Is bariatric surgery superior to a community weight management intervention in sustaining the weight loss necessary to achieve sustained remission among patients with idiopathic intracranial hypertension?
S. Mollan, J. Mitchell, R. Ottridge, Magda Aguiar, A. Yiangou, Z. Alimajstorovic, D. Cartwright, O. Grech, G. Lavery, C. Westgate, V. Vijay, W. Scotton, B. Wakerley, T. Matthews, A. Ansons, S. Hickman, J. Benzimra, C. Rick, R. Singhal, A. Tahrani, K. Brock, E. Frew, A. Sinclair   +22 more
semanticscholar   +1 more source

Intracranial Efficacy of Selpercatinib in RET Fusion-Positive Non–Small Cell Lung Cancers on the LIBRETTO-001 Trial

Clinical Cancer Research, 2021
Purpose: We report the intracranial efficacy of selpercatinib, a highly potent and selective RET inhibitor, approved in the United States for RET fusion-positive non–small cell lung cancers (NSCLC).
V. Subbiah, J. Gainor, G. Oxnard, D. Tan, D. Owen, B. Cho, H. Loong, C. McCoach, J. Weiss, Y. J. Kim, L. Bazhenova, Keunchil Park, H. Daga, B. Besse, O. Gautschi, C. Rolfo, E. Zhu, J. Kherani, Xin Huang, Suhyun Kang, A. Drilon   +20 more
semanticscholar   +1 more source

Intracranial Efficacy and Survival With Tucatinib Plus Trastuzumab and Capecitabine for Previously Treated HER2-Positive Breast Cancer With Brain Metastases in the HER2CLIMB Trial

Journal of Clinical Oncology, 2020
PURPOSE In the HER2CLIMB study, patients with human epidermal growth factor receptor 2 (HER2)–positive breast cancer with brain metastases (BMs) showed statistically significant improvement in progression-free survival (PFS) with tucatinib.
N. Lin, V. Borges, C. Anders, R. Murthy, E. Paplomata, E. Hamilton, S. Hurvitz, S. Loi, A. Okines, V. Abramson, Philippe Bédard, Mafalda Oliveira, V. Mueller, A. Zelnak, M. DiGiovanna, T. Bachelot, A. J. Chien, R. O'Regan, A. Wardley, A. Conlin, D. Cameron, L. Carey, G. Curigliano, K. Gelmon, S. Loibl, J. Mayor, S. McGoldrick, Xuebei An, E. Winer   +28 more
semanticscholar   +1 more source

Intracranial imaging [PDF]

Postgraduate Medical Journal, 1996
Summary This article concentrates on the imaging of intracranial structures and outlines some basic imaging strategies for common clinical presentations.
Gibson, M, Cook, Gary, Al-Kutoubi, A
openaire   +3 more sources

Orbital tuberculosis in childhood with intracranial extension: a case report

The CASE Journal, 2010
The common causes of orbital masses in pediatric age group include pseudotumour, lymphomas, hemangioma and dermoid cyst. Orbital tuberculosis is rare especially in children.
Navneet Tuli
semanticscholar   +1 more source

Cerebrospinal Fluid Pressure-Related Features in Chronic Headache: A Prospective Study and Potential Diagnostic Implications

Frontiers in Neurology, 2018
Objective: To identify the pressure-related features of isolated cerebrospinal fluid hypertension (ICH) in order to differentiate headache sufferers with ICH from those with primary headache disorder.Methods: In this prospective study, patients with ...
Francesco Bono, Francesco Bono, Maria Curcio, Laura Rapisarda, Basilio Vescio, Caterina Bombardieri, Domenica Mangialavori, Umberto Aguglia, Aldo Quattrone   +8 more
doaj   +1 more source

Suspected Primary Intracranial Melanoma with Widespread Distant Metastases in a Cat

Animals, 2023
An 8-year-old female Domestic Shorthair presented with signs of intracranial disease. Magnetic resonance imaging (MRI) of the head showed an extra-axial space-occupying mass within the cranial vault with a similar intensity lesion within the overlying ...
Jonathan Deacon, Samuel Beck, Francesca Pitorri, Catherine Stalin   +3 more
doaj   +1 more source

Bistability breaks-off deterministic responses to intracortical stimulation during non-REM sleep

Frontiers in Systems Neuroscience, 2015
INTRODUCTION During non-rapid eye movement (NREM) sleep (stage N3), when consciousness fades, cortico-cortical interactions are impaired while neurons are still active and reactive(Tononi and Massimini, 2008). Why is this?
Andrea Pigorini, Paola Proserpio, Caroline Szymansky, Gabriele Arnulfo, Marcello Massimini   +4 more
doaj   +1 more source