IntrA: 3D Intracranial Aneurysm Dataset for Deep Learning [PDF]
Medicine is an important application area for deep learning models. Research in this field is a combination of medical expertise and data science knowledge. In this paper, instead of 2D medical images, we introduce an open-access 3D intracranial aneurysm dataset, IntrA, that makes the application of points-based and mesh-based classification and ...
arxiv
ABSTRACT Introduction We aimed to assess the impact of introduction of a dedicated trauma surgical unit (TSU) on CT utilisation for polytrauma in the Emergency Department (ED). Methods Single centre retrospective cohort study comparing adult patients undergoing CT for polytrauma following TSU introduction (Intervention group, n = 617) to a historical ...
Rebecca Hong+11 more
wiley +1 more source
Machine learning algorithms to predict the risk of rupture of intracranial aneurysms: a systematic review [PDF]
Purpose: Subarachnoid haemorrhage is a potentially fatal consequence of intracranial aneurysm rupture, however, it is difficult to predict if aneurysms will rupture. Prophylactic treatment of an intracranial aneurysm also involves risk, hence identifying rupture-prone aneurysms is of substantial clinical importance.
arxiv +1 more source
Intracranial hemodynamics simulations: An efficient and accurate immersed boundary scheme [PDF]
Computational fluid dynamics (CFD) studies have been increasingly used for blood flow simulations in intracranial aneurysms (ICAs). However, despite the continuous progress of body-fitted CFD solvers, generating a high quality mesh is still the bottleneck of the CFD simulation, and strongly affects the accuracy of the numerical solution.
arxiv
The FRED‐X Flow Diverter—An Australian Experience
ABSTRACT Background The FRED X flow diverter features antithrombotic surface treatment to reduce thrombogenicity. This study evaluated the safety and efficacy of FRED X in treating intracranial aneurysms in the Australian setting. Methods Clinical, procedural and imaging data were retrospectively reviewed for a consecutive series of patients at a ...
Peter Shuangyue Tan+6 more
wiley +1 more source
Non-Kolmogorov Turbulence and Inverse Energy Cascade in Intracranial Aneurysm: Near-Wall Scales Suggest Mechanobiological Relevance [PDF]
The genesis, growth and rupture of intracranial aneurysm (IA) are open questions in neurovascular medicine until the present moment. The complexity of aneurysm mechanobiology and pathobiology staggeringly combine intertwining biological and physical processes that are tightly connected.
arxiv
Transitional flow in intracranial aneurysms - a space and time refinement study below the Kolmogorov scales using Lattice Boltzmann Method [PDF]
Most Computational Fluid Dynamics (CFD) studies of hemodynamics in intracranial aneurysms are based on the assumption of laminar flow due to a relatively low (below 500) parent artery Reynolds number. A few studies have recently demonstrated the occurrence of transitional flow in aneurysms, but these studies employed special finite element schemes ...
arxiv
Intra-operative Optimal Flow Diverter Selection for Intracranial aneurysm treatment [PDF]
During intracranial aneurysm (IA) treatment with Diverters (FDs), the device/parent artery diameters ratio may influence the ability of the device to induce aneurysm healing response. Oversized FDs are safer to deploy but may not induce enough hemodynamic resistance to ensure aneurysm occlusion. Methods based on Computational Fluid Dynamics (CFD) could
arxiv +1 more source
Toward molecular phenotyping of temporal lobe epilepsy by spatial omics
Abstract Objective In temporal lobe epilepsy (TLE), detection of the epileptogenic zone predicts a good surgical outcome. When submitted to 18F‐fluorodeoxyglucose positron emission tomography (PET), some patients display lateralized, focal hypometabolism in the temporal lobe (PET+), whereas others appear normometabolic (PET−).
Isabeau Vermeulen+33 more
wiley +1 more source
What's new? Due to the nature of cancer treatments, childhood cancer survivors have an increased risk of serious adverse events later in life. Here, the authors examined the incidence of cerebrovascular events (CVEs) among childhood cancer survivors who had received upper body radiotherapy.
Lisanne C. Verbruggen+28 more
wiley +1 more source