Inborn errors of immunity in children with neuroinflammation
Abstract Inborn errors of immunity (IEIs), an expanding group of monogenic disorders with diverse clinical manifestations, are increasingly recognized to include neuroinflammatory disease. Examples of diseases included under this umbrella are Aicardi–Goutières syndrome, deficiency of adenosine deaminase 2, familial haemophagocytic lymphohistiocytosis ...
Eppie M Yiu +5 more
wiley +1 more source
A clinical activation protocol improves response time to urgent/emergent neurosurgical care in children with brain tumors and intracranial hemorrhage. [PDF]
Jain R +7 more
europepmc +1 more source
Abstract Aim To characterize reported perinatal complications and childhood neurological diagnoses among children with COL4A1/2 variants and explore associations between mode of delivery and selected neurological outcomes. Method This was a retrospective cross‐sectional patient registry study using surveys collected through the Gould Syndrome ...
Shraddha Pandey +3 more
wiley +1 more source
Intracranial Hemorrhage After Mechanical Thrombectomy: Proximal Versus Distal MCA M1 Occlusions. [PDF]
Hasan D, Emrah A, Ferhat B, Kursad AC.
europepmc +1 more source
Intracranial Hemorrhage as the Primary Presentation of Metastatic Ewing Sarcoma: A Case Report. [PDF]
Cha A, Krel M.
europepmc +1 more source
ALOX15 links lipid metabolism to receptor trafficking in platelet activation
This schematic summarizes known and newly identified mechanisms of thrombin‐mediated platelet activation. In addition to classical thrombin‐induced PAR4 signaling pathways, thrombin activates an ALOX15–HETE–PKCθ–NMT1 signaling cascade that promotes protein myristoylation, facilitates receptor trafficking, and enhances PAR4 surface expression on ...
Yosef Eshetie Amare +2 more
wiley +1 more source
Between thrombosis and bleeding: the clinical dilemma of anticoagulation after intracranial hemorrhage. [PDF]
Ishimwe Mugisha A.
europepmc +1 more source
Machine-learning algorithms for detecting intracranial hemorrhage on head computed tomography. [PDF]
Goelz L +6 more
europepmc +1 more source
Traumatic brain injury in patients with mechanical heart valves on lifelong anticoagulation: incidence, management, and outcomes of intracranial hemorrhage. [PDF]
Feiereisen J +10 more
europepmc +1 more source
Clinical Characteristics and In-Hospital Course of Symptomatic Intracranial Hemorrhage After Intravenous Alteplase in Older Adults with Acute Ischemic Stroke: A Retrospective Cohort Study. [PDF]
Munteanu SN +9 more
europepmc +1 more source

