Results 101 to 110 of about 136,147 (343)

Arterial stiffening provides sufficient explanation for primary hypertension [PDF]

, 2013
Hypertension is one of the most common age-related chronic diseases and by predisposing individuals for heart failure, stroke and kidney disease, it is a major source of morbidity and mortality. Its etiology remains enigmatic despite intense research efforts over many decades.
arxiv   +1 more source

Costello Syndrome and Ophthalmologic Issues: Unveiling the Unseen

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Costello syndrome (CS) is an ultra‐rare condition belonging to the RASopathies, a group of disorders characterized by aberrant RAS/MAPK pathway signaling, which is involved in ocular development and in some eye pathologies. However, only a few studies assessing the ophthalmic features of individuals with CS are available.
Sofia Peschiaroli, Germana Viscogliosi, Annabella Salerni, Emanuele Crincoli, Roberta Mattei, Tommaso Verdolotti, Serafina Antonella Loprete, Valentina Trevisan, Giovanni Antonio Marrocco, Alessia Cherubino, Lucrezia Perri, Roberta Onesimo, Giuseppe Zampino, Chiara Leoni   +13 more
wiley   +1 more source

Pathophysiology of Idiopathic Intracranial Hypertension

Pediatric Neurology Briefs, 2012
Investigators at Emory University, Atlanta, GA review the epidemiology, pathophysiology and management of idiopathic intracranial hypertension (IIH), sometimes called pseudotumor cerebri or benign intracranial hypertension, terms now considered ...
J Gordon Millichap
doaj   +1 more source

Spontaneous intracranial hypotension : two steroid-responsive cases [PDF]

, 2018
Purpose: Spontaneous intracranial hypotension (SIH) is characterised by orthostatic headache, low cerebrospinal fluid pressure and diffuse pachymeningeal enhancement after intravenous gadolinium contrast administration.
Alexis, Zandolino, Andrea, Manto, Antonietta, Serino, Camilla, Russo, Giacomo, Fenza, Vincenzo, Buono   +5 more
core   +1 more source

Life's Essential 8 and midlife trajectories in cognition and brain health: The CARDIA study

Alzheimer's &Dementia, EarlyView.
Abstract INTRODUCTION Poor cardiovascular health (CVH) is linked to Alzheimer's disease and dementia; however, its association with neurocognitive trajectories earlier in life remains underexplored. METHODS We included 3224 participants with information on CVH at early midlife (mean age 45.0 ± standard deviation 3.4) an cognitive assessments, and ...
Christina Silvia Dintica, Xiaqing Jiang, Lenore J. Launer, R. Nick Bryan, Kristine Yaffe   +4 more
wiley   +1 more source

Collaborative learning of common latent representations in routinely collected multivariate ICU physiological signals [PDF]

In Intensive Care Units (ICU), the abundance of multivariate time series presents an opportunity for machine learning (ML) to enhance patient phenotyping. In contrast to previous research focused on electronic health records (EHR), here we propose an ML approach for phenotyping using routinely collected physiological time series data. Our new algorithm
arxiv   +1 more source

Worsening of cerebral hyperemia by the administration of terlipressin in acute liver failure with severe hepatic encephalopathy [PDF]

, 2004
There is increasing evidence that terlipressin is useful in patients with cirrhosis and hepatorenal syndrome, but there are no data of its use in patients with acute liver failure (ALF) in whom hepatorenal syndrome is common.
Davies, N.A., Hayes, P.C., Jalan, R., Lee, A., Mookerjee, R.P., Shawcross, D.L., Williams, R.   +6 more
core  

The perfect crime? : CCSVI not leaving a trace in MS [PDF]

, 2011
Background: Multiple sclerosis (MS) is a chronic, inflammatory demyelinating disease of the central nervous system, believed to be triggered by an autoimmune reaction to myelin.
Bechmann, Ingo Jürgen, Lorenz, Matthias, Mayer, Christoph, Nedelmann, Max, Pfeilschifter, Waltraud, Steinmetz, Helmuth, Ziemann, Ulf   +6 more
core   +3 more sources

Idiopathic intracranial hypertension [PDF]

Canadian Medical Association Journal, 2011
More than 93% of people with idiopathic intracranial hypertension (previously called pseudotumour cerebri and benign intracranial hypertension) are obese. The annual incidence of the disease is highest among young obese women, at an estimated 20 per 100 000.[1][1] The median age at onset is 34 ...
Michel J. Belliveau, Martin ten Hove
openaire   +3 more sources

Intravenous Thrombolysis in Patients Taking Direct Oral Anticoagulation Treatment Before Stroke Onset: Results from the Safe Implementations of Treatments in Stroke International Stroke Registry

Annals of Neurology, EarlyView.
Objectives Intravenous thrombolysis (IVT) is contraindicated for acute ischemic stroke (AIS) patients taking direct oral anticoagulants (DOACs) within 48 hours before index stroke. Limited data exist on off‐label use of IVT for these patients. We compared the safety and outcomes of IVT in AIS patients with DOAC treatment and patients with no OAC before
Marius Matusevicius, Malin Säflund, Maurizio Balestrino, Manuel Cappellari, Delfina Ferrandi, Abdoreza Ghoreishi, André Peeters, Viiu‐Marika Rand, Manuela De Michele, Aleksandras Vilionskis, Andrea Zini, Niaz Ahmed   +11 more
wiley   +1 more source