Results 241 to 250 of about 156,411 (348)

Risk of cardiac, neuropsychiatric and musculoskeletal adverse events with levothyroxine: Systematic review

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 4, Page 1023-1039, April 2026.
Abstract Levothyroxine (LT4) is the standard treatment for hypothyroidism and the most widely prescribed medication worldwide. Although generally safe, regulatory reports list potential cardiac, neuropsychiatric and musculoskeletal adverse events (AEs). Clarifying their clinical relevance is essential.
Bala Swetha Baskaran   +2 more
wiley   +1 more source

Routine Blood and Cerebrospinal Fluid Markers in Newly Diagnosed Idiopathic Intracranial Hypertension: An Exploratory Case-Control Study. [PDF]

open access: yesEye Brain
Hansen NS   +8 more
europepmc   +1 more source

Causal Relationship Between Neurotrophins and Normal Pressure Hydrocephalus: Insights From a Bidirectional Two‐Sample Mendelian Randomization Study

open access: yesBrain and Behavior, Volume 16, Issue 4, April 2026.
This Mendelian randomization study reveals that normal pressure hydrocephalus (NPH) causally leads to lower levels of the neurotrophins CNTF and GDNF. This finding provides new genetic evidence for the role of neurotrophic factors in NPH, suggesting potential avenues for further research into prevention and treatment strategies.
Tao Xu   +4 more
wiley   +1 more source

The Potential Functions and Beneficial Effects of Melatonin on Cognitive Impairment, Neuroinflammation, Blood–Brain Barrier Leakage, and Synaptic Dysfunction in the Offspring of Mice Exposed to Gestational Intermittent Hypoxia

open access: yesBrain and Behavior, Volume 16, Issue 4, April 2026.
Melatonin rescues the cognitive deficits induced by gestational intermittent hypoxia exposure in male offspring mice, and these results were associated with neuroinflammation, BBB integrity, and alterations in synaptic function. ABSTRACT Introduction Gestational intermittent hypoxia (GIH), which serves as a model for obstructive sleep apnea (OSA), is ...
Xue‐Yan Li   +6 more
wiley   +1 more source

Challenges in the management of intracranial hypertension in pediatric patients with HIV: a case report. [PDF]

open access: yesFront Med (Lausanne)
Cifuentes A   +5 more
europepmc   +1 more source

Molecular Evolutionary Insights Allow a Sequential Precision Medicine Strategy for Acquired Osimertinib Resistance in EGFR Mutant Non‐Small Cell Lung Cancer: Lessons From Longitudinal Tumor Sampling

open access: yesClinical Case Reports, Volume 14, Issue 4, April 2026.
Short Summary This report highlights the importance of rationally‐considered targeted combination treatments, identified by tumour genetic sequencing techniques in tissue and blood, in patients with metastatic NSCLC with EGFR mutation, through the lens of a patient's therapeutic journey.
Foteini Kalofonou   +4 more
wiley   +1 more source

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