Results 71 to 80 of about 697,686 (293)
Effect of Hyperosmolar Solutions on Cerebral Oxygenation and Metabolism
Общая реаниматология, 2008 Objective: to assess the time course of changes in the parameters of cerebral oxygenation and metabolism in the correction of intracranial hypertension with hyperosmolar solutions. Material and methods.
S. S. Petrikov +5 more
doaj +1 more source
Advanced Science, EarlyView.Subarachnoid hemorrhage (SAH) triggers monocyte‐derived macrophage (MDM) infiltration and M1‐like polarization via Vimentin upregulation, leading to neurovascular unit disruption and cognitive dysfunction. Remote ischemic postconditioning (RIPostC) upregulates neuronal Gas6, which activates Axl on MDMs to downregulate Vimentin and drive reparative M2 ...
Yajun Zhu +14 more
wiley +1 more source
Idiopathic Intracranial Hypertension
Pediatric Neurology Briefs, 2007 Sex distribution and frequency of obesity in children with idiopathic intracranial hypertension were evaluated at Meyer Children Hospital, Rappaport School of Medicine, Haifa, and other centers in Israel.
J Gordon Millichap
doaj +1 more source
The Costs of a Quiet Disorder: Direct and Indirect Costs of Idiopathic Intracranial Hypertension [PDF]
Idiopathic Intracranial Hypertension (IIH; pseudotumor cerebri) is a disorder with a reported incidence rate of one to three per 100,000 people in the general population.
Brenna Lobb +3 more
core
Advanced Science, EarlyView.A blue‐light‐crosslinked bilayer hydrogel was developed for local optic nerve repair. The adhesive GM‐Odex outer layer seals and anchors the lesion, while the non‐adhesive GM‐imid inner layer releases MPDA‐Cle without obstructing CSF flow. This system modulates oxidative and inflammatory microenvironments, supports oligodendrocyte differentiation and ...
Tonghe Pan +13 more
wiley +1 more source
Depression and Anxiety Symptoms in Idiopathic Intracranial Hypertension
, 2022 Patients with idiopathic intracranial hypertension (IIH) have been reported to have high prevalence of co-existent mood disorders. We investigated the frequency of symptoms of depression and anxiety in patients with IIH without a known psychiatric ...
Laura Donaldson; Michael Chen; Edward Margolin
core
Advanced Science, EarlyView.In this study, we demonstrate that aberrant MEKK3 signaling in endothelial cells and microglia drives the progression of cerebral cavernous malformations (CCMs). Furthermore, we identify DPDH as a potent small‐molecule MEKK3 inhibitor with substantial therapeutic potential for CCM treatment.
Weiwei Zheng +17 more
wiley +1 more source
The Use of Acetazolamide During Pregnancy in Intracranial Hypertension Patients
, 2013 Acetazolamide is the mainstay of medical therapy for idiopathic intracranial hypertension (IIH). Its use in pregnant women has not been recommended because of reported teratogenic effects in rodents and rabbits.
Julie Falardeau, MD; Brenna M. Lobb, MS, MPH; Sara Golden, MPH; Steven D. Maxfield, BS; Emanuel Tanne, MD
core
Role of Obstructive Sleep Apnea in Idiopathic Intracranial Hypertension
, 2023 It remains unclear if the presence or treatment of obstructive sleep apnea (OSA) influences the severity or natural history of Idiopathic Intracranial Hypertension (IIH).
Mangayarkarasi Thandampallayam Ajjeya; Padmaja Sudhakar
core
Advanced Science, EarlyView.This review presents a pathology‐driven framework unifying nanomedicine across TBI, SCI, and PNI. Epidemiological evidence and comparative single‐cell transcriptomic reanalysis define shared pathological modules, injury‐specific effectors, and therapeutic bottlenecks. Six functional paradigms connect nanomaterial structure and biological fate to injury‐
Mouyuan Sun +12 more
wiley +1 more source