Results 111 to 120 of about 235,338 (351)

Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive‐Like Behaviors

open access: yesAdvanced Science, EarlyView.
Chen et al. show that the endoplasmic reticulum (ER) stress sensor PERK is downregulated in prefrontal cortex (PFC) astrocytes in major depressive disorder and in chronic‐stress mouse models. In young mice, astrocyte‐specific PERK loss reduces the synaptogenic cue thrombospondin‐1 (TSP1), leading to synaptic and circuit deficits and depressive‐like ...
Kai Chen   +8 more
wiley   +1 more source

Increased Intracranial Pressure Following Removal of Intracranial Lesions [PDF]

open access: yesActa Medica Iranica, 1964
Increased intracramal tension may 0 ise some days or ''leeks the problem may ari 1 of lrelUova "nt r a cra nial tumours or . lfter operation. , ""n" . " such increased tensicn raises the pOSS1- In the immed.',iate postoperat1ve perlOd"
B. Ramamurthi
doaj   +2 more sources

Study of Intracranial Hematoma Removal and High Intracranial Pressure Reduction Using a Novel Three-Needle Brain Puncture Technique

open access: yesInternational Journal of General Medicine, 2022
Anjun Song,1,* Hui Yang,2,* Guofeng Wu,1 Siying Ren,1 Likun Wang,1 Guannan Qin,1 Yuanhong Mao1 1Emergency Department, The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, People’s Republic of China; 2Guiyang Public Health ...
Song A   +6 more
doaj  

High-Flow Vascular Malformations in Children. [PDF]

open access: yes, 2020
Children can have a variety of intracranial vascular anomalies ranging from small and incidental with no clinical consequences to complex lesions that can cause substantial neurologic deficits, heart failure, or profoundly affect development. In contrast
Abla, Adib A   +8 more
core  

Adenylyl Cyclase 8 in Dorsal CA1 Neurons Prevents Depressive‐Like Behaviors by Maintaining Neuronal Excitability and Glutamatergic Neurotransmission Through TIP39‐PTH2R Signaling

open access: yesAdvanced Science, EarlyView.
Depression, a prevalent neuropsychiatric disorder with unclear pathogenesis, involves dysfunctional adenylyl cyclase 8 (Adcy8) as a key risk factor. Chronic stress selectively reduces Adcy8 expression in the dorsal CA1 (dCA1) neurons. Depletion of Adcy8 in dCA1 excitatory neurons induces depressive‐like behaviors by impairing neuronal excitability and ...
Zi‐Jie Liu   +14 more
wiley   +1 more source

Rigid Hollow Microparticles for Enhanced Focused Ultrasound Treatment Under Optoacoustic Guidance

open access: yesAdvanced Science, EarlyView.
By combining focused ultrasound (FUS) and acoustically active hollow borosilicate microparticles (HBMPs), we demonstrate tunable control over interparticle dynamics and their localized thermal energy deposition. Modulation of acoustic frequency and particle concentration tailors the energy delivery, allowing adaptive, material‐based regulation of ...
Nima Mahkam   +6 more
wiley   +1 more source

[Intracranial pressure monitoring].

open access: yesRevista da Escola de Enfermagem da U S P, 1981
Este trabalho apresenta alguns aspectos básicos da monitorização intracraniana, necessários para o desempenho eficaz da enfermeira que assiste pacientes submetidos a esse procedimento.
openaire   +2 more sources

Assessing the Relative Importance of Imaging and Serum Biomarkers in Capturing Disability, Cognitive Impairment, and Clinical Progression in Multiple Sclerosis

open access: yesAdvanced Science, EarlyView.
Using machine‐learning analyses in two independent multiple sclerosis cohorts, spinal cord atrophy and cortical degeneration emerged as key predictors of disability and progression independent of relapses. Deep gray matter damage further improved prediction, while serum biomarkers of brain damage provided complementary information, highlighting the ...
Alessandro Cagol   +17 more
wiley   +1 more source

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