Results 61 to 70 of about 4,989,210 (357)

Positive End-Expiratory Pressure as a Factor Influencing Cerebral Perfusion Pressure (an experimental study)

Общая реаниматология, 2012
Objective: to evaluate the effect of positive end-expiratory pressure (PEEP) on cerebral perfusion pressure (CPP) in intracranial hypertension in an experiment using a biological model. Materials and methods.
V. E. Leshkova, Sh. V. Timerbulatov, M. A. Sadritdinov, V. M., Sibayev, R. F. Galeyev, B. I. Gimatdinov, R. M. Sakhautdinov   +6 more
doaj   +1 more source

Intracranial Pressure Is a Determinant of Sympathetic Activity

Frontiers in Physiology, 2018
Intracranial pressure (ICP) is the pressure within the cranium. ICP rise compresses brain vessels and reduces cerebral blood delivery. Massive ICP rise leads to cerebral ischemia, but it is also known to produce hypertension, bradycardia and respiratory ...
E. Schmidt, F. Despas, A. Pavy-Le Traon, Z. Czosnyka, J. Pickard, K. Rahmouni, A. Pathak, J. Sénard   +7 more
semanticscholar   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Refractory Intracranial Hypertension due to Fentanyl Administration Following Closed Head Injury

Frontiers in Neurology, 2013
BackgroundAlthough the effects of opioids on intracranial pressure have long been a subject of controversy, they are frequently administered to patients with severe head trauma.
Sara E Hocker, Jeremy L Fogelson, Alejandro eRabinstein   +2 more
doaj   +1 more source

Complications of invasive intracranial pressure monitoring devices in neurocritical care.

Neurosurgical Focus, 2017
Intracranial pressure monitoring devices have become the standard of care for the management of patients with pathologies associated with intracranial hypertension.
Samon G Tavakoli, G. Peitz, W. Ares, Shaheryar Hafeez, R. Grandhi   +4 more
semanticscholar   +1 more source

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp, Ludwig Karrasch, Helena Breitenstein, Andreas Straube, Katharina Kamm   +4 more
wiley   +1 more source

Characterization of intracranial pressure behavior in chronic epileptic animals: a preliminary study

, 2016
Intracranial pressure (ICP) is a major neurological parameter in animals and humans. ICP is a function of the relationship between the contents of the cranium (brain parenchyma, cerebrospinal fluid, and blood) and the volume of the skull.
Cardim, Ana Carolina, Ana Carolina Cardim, Pacheco Andrade, Rodrigo de Albuquerque, Malheiros, Jackeline Moraes [UNIFESP], Jackeline Moraes Malheiros, Tannus, Alberto, Covolan, Luciene [UNIFESP], Charles Chenwei Wang, Frigieri, Gustavo Henrique, Brenno Caetano Troca Cabella, Troca Cabella, Brenno Caetano, Alberto Tannús, Gustavo Henrique Frigieri, Luciene Covolan, Cardim, Danilo Augusto, Wang, Charles Chenwei, Mascarenhas, Sergio, Sérgio Mascarenhas, Danilo Augusto Cardim, Rodrigo de Albuquerque Pacheco Andrade   +19 more
core   +1 more source

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng, Diego Z. Carvalho, Shahid Karim, Anwar Chahal, Virend K. Somers   +4 more
wiley   +1 more source

A novel rat model to study the role of intracranial pressure modulation on optic neuropathies. [PDF]

PLoS ONE, 2013
Reduced intracranial pressure is considered a risk factor for glaucomatous optic neuropathies. All current data supporting intracranial pressure as a glaucoma risk factor comes from retrospective and prospective studies.
Uttio Roy Chowdhury, Bradley H Holman, Michael P Fautsch   +2 more
doaj   +1 more source

Comprehensive Assessment of Arterial, Tissue, and Venous Collaterals for Evaluating the Infarct Growth Rate: The Multimodal Collateral Score

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Collaterals are crucial factors that influence the infarct growth rate (IGR). We aimed to determine whether a comprehensive multimodal collateral score (MCS), incorporating collateral assessment at the arterial, tissue, and venous levels, is associated with functional independence and provides incremental prognostic value over ...
Giorgio Busto, Umberto Pensato, Ilaria Casetta, Giorgio U. Marcello, Angelo Barra, Anna Poggesi, Edoardo Carlesi, Sara Mancini, Andrea Ginestroni, Vittorio Miele, Alessandro Padovani, Andrea Morotti, Enrico Fainardi   +12 more
wiley   +1 more source