Objective: to evaluate the effect of positive end-expiratory pressure (PEEP) on cerebral perfusion pressure (CPP) in intracranial hypertension in an experiment using a biological model. Materials and methods.
V. E. Leshkova +6 more
doaj +1 more source
Intracranial Compliance Assessed by Intracranial Pressure Pulse Waveform
Background: Morphological alterations in intracranial pressure (ICP) pulse waveform (ICPW) secondary to intracranial hypertension (ICP >20 mmHg) and a reduction in intracranial compliance (ICC) are well known indicators of neurological severity.
Sérgio Brasil +5 more
doaj +1 more source
Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
Refractory Intracranial Hypertension due to Fentanyl Administration Following Closed Head Injury
BackgroundAlthough the effects of opioids on intracranial pressure have long been a subject of controversy, they are frequently administered to patients with severe head trauma.
Sara E Hocker +2 more
doaj +1 more source
A novel rat model to study the role of intracranial pressure modulation on optic neuropathies. [PDF]
Reduced intracranial pressure is considered a risk factor for glaucomatous optic neuropathies. All current data supporting intracranial pressure as a glaucoma risk factor comes from retrospective and prospective studies.
Uttio Roy Chowdhury +2 more
doaj +1 more source
Location‐Specific Hematoma Volume Predicts Early Neurological Deterioration in Supratentorial ICH
ABSTRACT Objective Early neurological deterioration (END) adversely affects outcomes in patients with intracerebral hemorrhage (ICH). This study aimed to determine the location‐specific hematoma volumes for END in supratentorial ICH patients. Methods We retrospectively analyzed supratentorial ICH patients presenting from two prospective cohorts.
Zuoqiao Li +10 more
wiley +1 more source
Imaging characteristics and treatment of a penetrating brain injury caused by an oropharyngeal foreign body in a dog [PDF]
A 4-year-old Border collie was presented with one episode of collapse, altered mentation, and a suspected pharyngeal stick injury. Magnetic resonance imaging (MRI) and computed tomography showed a linear foreign body penetrating the right oropharynx ...
Baroni M. +15 more
core +1 more source
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang +8 more
wiley +1 more source
Non-invasive method of measuring cerebral spinal fluid pressure [PDF]
The invention provides a method of non-invasively determining intracranial pressure from measurements of an eye. A parameter of an optic nerve of the eye is determined, along with an intraocular pressure of the eye.
Borchert, Mark S., Lambert, James L.
core +1 more source
New experimental model of acute aqueductal blockage in cats: effects on cerebrospinal fluid pressure and the size of brain ventricles [PDF]
It is generally assumed that cerebrospinal fluid (CSF) is secreted in the brain ventricles, and so after an acute blockage of the aqueduct of Sylvius an increase in the ventricular CSF pressure and dilation of isolated ventricles may be expected. We have
Božić, Borka +5 more
core +1 more source

