Results 161 to 170 of about 551,832 (300)

Effect of artificial gravity on calcaneal bone marrow adipose tissue and mineral content in female and male participants in 60 days of bed rest

open access: yesExperimental Physiology, EarlyView.
Abstract Modulation of bone marrow adipose tissue (BMAT) with prolonged inactivity was reported in haemopoietic but not in non‐haemopoietic bones. This prospective randomized controlled trial submitted 16 men and 8 women to 60 days of 6° head‐down‐tilt bed rest.
Tammy Liu   +5 more
wiley   +1 more source

Treatment Landscape in Pediatric Immune Thrombocytopenia: Addressing Unmet Needs

open access: yesPediatric Blood &Cancer, Volume 72, Issue 7, July 2025.
ABSTRACT Pediatric immune thrombocytopenia (ITP) is associated with a multifaceted burden on children and their parents/caregivers due to bleeding, fatigue, activity restrictions, and psychological distress. Most children recover within 12 months, but up to 30% develop chronic ITP.
Joana Azevedo   +4 more
wiley   +1 more source

Acute Mastoiditis Complicated with Concomitant Bezold’s Abscess and Lateral Sinus Thrombosis

open access: yesCase Reports in Otolaryngology, 2018
Bezold’s abscess is a very rare extracranial complication of acute mastoiditis. Lateral sinus thrombosis is another intracranial complication of acute mastoiditis that can occur, but there are only few reports of concomitant ispilateral Bezold’s abscess ...
Aziz Mustafa   +4 more
doaj   +1 more source

A Comparison between Recombinant Activated Factor VII (Aryoseven) and Novoseven in Patients with Congenital Factor VII Deficiency [PDF]

open access: yes, 2015
In order to establish the efficacy and biosimilar nature of AryoSeven to NovoSeven in the treatment of congenital factor VII (FVII) deficiency, patients received either agent at 30 1/4g/kg, intravenously per week for 4 weeks, in a randomized fashion. The
Abolghasemi, H.   +16 more
core  

Higher versus lower mean arterial blood pressure after cardiac arrest and resuscitation (MAP‐CARE): A protocol for a randomized clinical trial

open access: yesActa Anaesthesiologica Scandinavica, Volume 69, Issue 6, July 2025.
Abstract Background In patients resuscitated after cardiac arrest, a higher mean arterial pressure (MAP) may increase cerebral perfusion and attenuate hypoxic brain injury. Here we present the protocol of the mean arterial pressure after cardiac arrest and resuscitation (MAP‐CARE) trial aiming to investigate the influence of MAP targets on patient ...
V. H. Niemelä   +77 more
wiley   +1 more source

Differential Features of Culprit Intracranial Atherosclerotic Lesions: A Whole-Brain Vessel Wall Imaging Study in Patients With Acute Ischemic Stroke. [PDF]

open access: yes, 2018
BackgroundIntracranial atherosclerotic disease tends to affect multiple arterial segments. Using whole-brain vessel wall imaging, we sought to study the differences in plaque features among various types of plaques in patients with a recent unilateral ...
Bi, Xiaoming   +12 more
core  

Rilzabrutinib for the Treatment of Immune Thrombocytopenia

open access: yesEuropean Journal of Haematology, Volume 115, Issue 1, Page 4-15, July 2025.
ABSTRACT Advancements in the understanding of ITP pathogenesis have led to significant improvements in disease management through the use of both traditional immunosuppressive strategies and novel targeted therapies. However, a subset of patients remains refractory to treatment or achieves only transient benefits, underscoring the need for alternative ...
Caterina Labanca   +12 more
wiley   +1 more source

White Matter Microstructure Alterations in Older Adults With Dyslipidemia Associated With Cognitive and Locomotor Dysfunction Evaluated Using Neurite Orientation Dispersion and Density Imaging

open access: yesBrain and Behavior, Volume 15, Issue 6, June 2025.
This study used NODDI to identify white matter microstructure alterations in older adults with dyslipidemia, revealing significantly reduced neurite density in several brain regions. These reductions were linked to declines in cognitive and motor functions, suggesting that NODDI may serve as a biomarker for dyslipidemia‐related axonal degeneration ...
Zaimire Mahemuti   +12 more
wiley   +1 more source

Long‐term outcomes of apixaban as main anticoagulant in patients with HeartMate 3 left ventricular assist devices

open access: yesESC Heart Failure, Volume 12, Issue 3, Page 1714-1718, June 2025.
Abstract Aims HeartMate 3 (HM3) left ventricular assist devices (LVADs) offer improved haemocompatibility‐related outcomes for end‐stage heart failure patients, facilitating the exploration of alternative anticoagulation therapies beyond warfarin.
Jennifer Jdaidani   +7 more
wiley   +1 more source

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