Results 211 to 220 of about 80,194 (337)

Emicizumab in Previously Untreated Patients and Minimally Treated Patients With Hemophilia A: A Comparative Study Between Two International Cohorts

open access: yesPediatric Blood &Cancer, Volume 73, Issue 1, January 2026.
ABSTRACT Background Hemophilia A (HA) is a rare bleeding disorder caused by coagulation factor VIII (FVIII) deficiency. Prophylactic FVIII replacement therapy is essential for preventing bleeds, but it carries a risk of inhibitor development, especially in previously untreated and minimally treated patients (PUPs and MTPs, respectively).
Sarina Levy‐Mendelovich   +11 more
wiley   +1 more source

[Intracranial venous thrombosis].

open access: yesGaceta medica de Mexico, 1978
J H, Mateos-Gómez   +3 more
openaire   +1 more source

Population Pharmacokinetics of Asundexian in People at Risk for Thromboembolic/Cardiovascular Events

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 1, January 2026.
ABSTRACT Asundexian is a potent, selective, and reversible inhibitor of activated clotting Factor XI currently under development for secondary prevention of recurrent ischemic stroke in the ongoing Phase III OCEANIC‐STROKE study (NCT05686070). Here, we report the development of a population pharmacokinetic (popPK) model for asundexian.
Ashraf Yassen   +7 more
wiley   +1 more source

Association Between Pulse Wave Velocity and Cerebral Small Vessel Disease: A Scoping Review. [PDF]

open access: yesCureus
Kahook Z   +5 more
europepmc   +1 more source

Percutaneous Reperfusion Therapies vs. Anticoagulation in Patients With Acute Intermediate‐High‐Risk Pulmonary Embolism: The PRETHA Randomized Clinical Trial

open access: yesPulmonary Circulation, Volume 16, Issue 1, January 2026.
ABSTRACT The optimal treatment strategy for patients with acute intermediate–high‐risk pulmonary embolism (PE) remains uncertain. This randomized clinical trial (PRETHA) aimed to evaluate the efficacy and safety of percutaneous reperfusion therapies—trans‐catheter thrombectomy and trans‐catheter thrombolysis—compared with standard anticoagulation ...
Taida Ivanauskienė   +9 more
wiley   +1 more source

Platelet dysfunction in immune thrombocytopenia: Finding clinical subsets with platelet phenotypes

open access: yesBritish Journal of Haematology, Volume 208, Issue 1, Page 274-284, January 2026.
Summary Patients with immune thrombocytopenia (ITP) remain a challenge to diagnose, manage and predict bleeding risk. A comprehensive assessment of platelet function may aid clinical management. This study assessed platelet parameters to predict bleeding in ITP.
Sidra A. Ali   +9 more
wiley   +1 more source

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