Results 41 to 50 of about 52,985 (192)

UK Infected Blood Inquiry–An Historical Appraisal

Haemophilia, EarlyView.
ABSTRACT Introduction This appraisal considers the 2018 UK Infected Blood Inquiry and its Report (2024) in the context of the history of haemophilia treatment developments over the past fifty‐five years, and the tragic impacts of the AIDS pandemic. Aim The paper appraises the conduct and findings of the IBI and its Report in relation to HIV and AIDS ...
Christopher A. Ludlam
wiley   +1 more source

Management of Breakthrough Bleeding During Emicizumab Prophylaxis in Acquired Haemophilia A: Data From the GTH‐AHA‐EMI Study

Haemophilia, EarlyView.
ABSTRACT Introduction The GTH‐AHA‐EMI study showed that emicizumab reduces bleeding in patients with acquired haemophilia A (AHA). However, 22 clinically relevant new bleeds (CRNB) occurred in 14 of the 47 study patients, most of which required haemostatic treatment.
Halet Türkantoz, Christiane Dobbelstein, Richard Greil, Christina Hart, Robert Klamroth, Paul Knöbl, Johannes Oldenburg, Christian Pfrepper, Ulrich Sachs, Inga M. Schimansky, Karolin Trautmann‐Grill, Andreas Tiede   +11 more
wiley   +1 more source

Recognizing Signs of Abusive Head Trauma

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Background Abusive head trauma (AHT) remains the leading cause of fatal traumatic brain injury in infants and young children. Diagnosis is frequently delayed or missed due to nonspecific clinical presentation and unreliable histories, making neuroimaging a critical component of the diagnostic process. Objective This review synthesises computed
Maísa Naomi Irie, Vinicius de Menezes Jarry, Matheus de Lima Ruffini, Adolfo Moraes de Souza, Mariana Dalaqua, Juliana Ávila Duarte, Andrea Fraga, Fabiano Reis   +7 more
wiley   +1 more source

Evaluating the effects of a hospital utilisation improvement program on platelet transfusions: A pre‐post study

Transfusion Medicine, EarlyView.
Abstract Background Annually millions of platelet concentrate (PC) are transfused worldwide. The decision regarding PC transfusion is often complex; therefore, the implementation of a hospital programme designed to streamline and facilitate the decision‐making process is beneficial. Such a programme helps standardise transfusion practices, ensures that
Piotr F. Czempik, Jakub Rudzki, Michał Porada   +2 more
wiley   +1 more source

Cardiovascular Outcomes With SGLT‐2 Inhibitors in Patients With Type 2 Diabetes and Obstructive Sleep Apnoea: A Real‐World Analysis

Diabetes, Obesity and Metabolism, EarlyView.
Reuben L. Odai, Dennis Dela Tsagli, Anthony Alchaer, Laiba Sajjad, Kwame Adjei‐Sefah, Chukwuemeka Aghasili, Smith Frimpong, Hussam Farhoud   +7 more
wiley   +1 more source

Transfusion of blood products to neonatal and pediatric extracorporeal membrane oxygenation patients: A prospective, observational study

Transfusion, EarlyView.
Abstract Study Question To describe the blood product utilization during neonatal and pediatric extracorporeal membrane oxygenation (ECMO) and to determine whether its usage correlates with clinical outcomes of bleeding, thrombosis or mortality. Design Prospective observational study of neonatal and pediatric ECMO patients from September 2016, until ...
Rebecca Barton, Suelyn Van Den Helm, Hui Ping Yaw, Chantal Attard, Graeme MacLaren, Vera Ignjatovic, Natasha Letunica, Vasiliki Karlaftis, Tengyi Cai, Amy Johansen, Derek Best, Roberto Chiletti, Yves d'Udekem, Jo McKittrick, Warwick Butt, Paul Monagle   +15 more
wiley   +1 more source

Maternal–fetal platelet alloimmunization: Identification of risk factors for severe neonatal thrombocytopenia

Transfusion, EarlyView.
Abstract Background Feto‐maternal platelet alloimmunization (FNAIT) is a rare condition (1 in 1500 live pregnancies), most commonly diagnosed based on clinical neonatal hemorrhagic manifestations, which can vary in severity. The aim of our study was to identify risk factors for severe fetal/neonatal thrombocytopenia in cases of FNAIT.
Elise Deroubaix, Marie‐Hélène Emektas, Gauthier Alluin, Pascale Renom, Fanny Rodermann, Mélissa Gilbert, Charles Garabedian, Véronique Houfflin‐Debarge   +7 more
wiley   +1 more source

The clinical use of cryoprecipitate and fibrinogen concentrate: A scoping review

Transfusion, EarlyView.
Abstract Background Acquired hypofibrinogenemia poses significant bleeding risks. Concentrated sources of fibrinogen, whether cryoprecipitate or fibrinogen concentrates, are widely used. This scoping review aimed to identify and map the available evidence on fibrinogen supplementation.
Aaron S. Hess, Sandra K. White, Elizabeth P. Crowe, Jay S. Raval, Jennifer Andrews, Claudia S. Cohn, Mischa L. Covington, Melissa M. Cushing, Cyril Jacquot, Jenna Khan, Anil K. Panigrahi, Nabiha H. Saifee, Aaron A. R. Tobian, Mary M. McFarland, Simon J. Stanworth, Ryan A. Metcalf   +15 more
wiley   +1 more source

Effect of artificial gravity on calcaneal bone marrow adipose tissue and mineral content in female and male participants in 60 days of bed rest

Experimental Physiology, EarlyView.
Abstract Modulation of bone marrow adipose tissue (BMAT) with prolonged inactivity was reported in haemopoietic but not in non‐haemopoietic bones. This prospective randomized controlled trial submitted 16 men and 8 women to 60 days of 6° head‐down‐tilt bed rest.
Tammy Liu, Gerd Melkus, Tim Ramsay, Alain Berthiaume, Gabriele Armbrecht, Guy Trudel   +5 more
wiley   +1 more source

An eye on long‐duration spaceflight: Controversies, countermeasures and challenges

Experimental Physiology, EarlyView.
Abstract Space flight‐associated neuroocular syndrome (SANS) is a consequence of long‐duration space flight and is detected in two‐thirds of astronauts. In‐flight, this can cause a change in the refraction of the eyes, requiring graded hypermetropic ‘superfocus adjustable’ glasses, optic nerve head oedema and choroidal folds.
Vincent Wing Sum Ng, Susan Patricia Mollan   +1 more
wiley   +1 more source