Results 101 to 110 of about 88,298 (320)

Cognitive Outcome After Deep Brain Stimulation for Refractory Obsessive–Compulsive Disorder: A Systematic Review

open access: yesNeuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Introduction Deep brain stimulation (DBS) is an effective treatment for refractory obsessive–compulsive disorder (OCD). Neuropsychological assessment contributes to DBS treatment in several ways: it monitors the cognitive safety of the treatment, identifies beneficial or detrimental cognitive side effects and it could aid to explain ...
Tim A. M. Bouwens van der Vlis   +7 more
wiley   +1 more source

Mental health aspects and the doctor-patient relationship do matter in the management of refractory chronic pain

open access: yesO Mundo da Saúde
Chronic non-cancer pain (CNCP) is among the clinical conditions that most challenge curative medicine due to its high therapeutic failure rates. In many cases, pain management teams are unable to identify a clear organic cause for the pain condition; in ...
João Paulo Consentino Solano   +3 more
doaj   +1 more source

Functional bowel disease : a challenging frontier in gastroenterology [PDF]

open access: yes, 1999
The last 30 years have seen incredible advances in the science and practice of gastroenterology and hepatology. In the 1970s, the fiberoptic endoscopic revolution facilitated the visualization of the mucosa of a large segment of the gastrointestinal ...
Camilleri, Michael
core  

Pain sensitivity: an unnatural history from 1800 to 1965 [PDF]

open access: yes, 2014
Who was truly capable of experiencing pain? In this article, I explore ideas about the distribution of bodily sensitivity in patients from the early nineteenth century to 1965 in Anglo-American societies.
Bourke, Joanna
core   +1 more source

Efficacy and Safety of the Topical Gene Therapy Beremagene Geperpavec‐svdt (B‐VEC) in an Open‐Label Study of Japanese Subjects With Dystrophic Epidermolysis Bullosa

open access: yesThe Journal of Dermatology, EarlyView.
ABSTRACT Dystrophic epidermolysis bullosa (DEB) patients have pathogenic variants in COL7A1, leading to skin fragility, blistering, and scarring. Beremagene geperpavec‐svdt (B‐VEC) is a replication‐defective herpes simplex virus type 1 (HSV‐1)‐based gene therapy vector administered topically to deliver functional COL7A1 to DEB wounds.
Ken Natsuga   +12 more
wiley   +1 more source

Computation of atomic astrophysical opacities

open access: yes, 2018
The revision of the standard Los Alamos opacities in the 1980-1990s by a group from the Lawrence Livermore National Laboratory (OPAL) and the Opacity Project (OP) consortium was an early example of collaborative big-data science, leading to reliable data
Mendoza, Claudio
core   +1 more source

How the political elite make decisions

open access: yesAustralian Journal of Public Administration, EarlyView.
Abstract The political elite make policy decisions in noisy environments and under time pressure, and so are prone to using heuristics. There are conflicting schools of thought as to whether it is appropriate for them to do so. Experienced decision‐makers are thought to be more effective at using heuristics, so it is possible that for the political ...
Conor Wynn, Liam Smith, Catherine Killen
wiley   +1 more source

The Tragedy of Painless Needs

open access: yesPain Research and Management, 2000
Intractable pain demands the attention of both the patient and the physician. However, modern science and medicine cannot and should not promise the abolition of pain and suffering.
John D Loeser
doaj   +1 more source

Erector spinae plane block for intractable, nonsurgical abdominal pain: a scoping review [PDF]

open access: yesClinical and Experimental Emergency Medicine
Abdominal pain is one of the most common presenting chief complaints in the emergency department. Erector spinae plane block (ESPB) is an ultrasound-guided nerve block with proven effectiveness in treating visceral and somatic abdominal pain. Despite the
Ashley Meyer   +8 more
doaj   +1 more source

Depression, Critique, and Critical Theory as Political Therapy

open access: yesConstellations, EarlyView.
ABSTRACT Critical theorists, especially in the Frankfurt School tradition, claim that normative thought and critique arise from experiences of suffering and oppression. It seems intuitive that oppression sometimes makes people sad and angry in ways that motivate critique and resistance; yet, other times, it leads to debilitating experiences of ...
Jasper Friedrich
wiley   +1 more source

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