The Immuno-Suppressive Effects of Cyclic, Environmental Heat Stress in Broiler Chickens: Local and Systemic Inflammatory Responses to an Intradermal Injection of Lipopolysaccharide. [PDF]
Rocchi AJ +6 more
europepmc +1 more source
Geometry Analysis of Two Photon Polymerized Microneedles—An Experimental and Simulated Approach
This research investigates the mechanical stability of hollow, two‐photon‐polymerized microneedles for drug delivery. In an experimental setup, a steel stamp gradually compresses 1000 μm‐tall microneedles while recording their force–deformation response.
Cordelia F. Wittemann +4 more
wiley +1 more source
Additional Evidence Fails to Associate Variation in KCNE4 With Equine Anhidrosis
ABSTRACT A prior genome‐wide association (GWA; N = 200) including Thoroughbreds and stock horses implicated chromosome 6 (NC_009149.3) in owner‐reported equine anhidrosis. A missense variant in KCNE4 (NC_009149.3:g.11813731A>G) was proposed as a risk allele, although its association with anhidrosis was not reported.
Jessica L. Petersen, Carrie J. Finno
wiley +1 more source
Guinea pigs sublethally infected with aerosolized Legionella pneumophila develop humoral and cell-mediated immune responses and are protected against lethal aerosol challenge. A model for studying host defense against lung infections caused by intracellular pathogens. [PDF]
We have employed the guinea pig model of L. pneumophila infection, which mimics Legionnaires' disease in humans both clinically and pathologically, to study humoral and cell-mediated immune responses to L.
Breiman, RF, Horwitz, MA
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HIF2A as a prognostic and clinical therapeutic target in ovarian clear cell carcinoma
What's new? Ovarian clear cell carcinoma is highly associated with hypoxia. Hypoxia‐inducible factor 2A (HIF2A) is a key regulator of hypoxic responses, but its role in ovarian clear cell carcinoma remains unclear. This study demonstrated the unfavorable prognostic significance of HIF2A expression in ovarian clear cell carcinoma.
Mengxin Jiang +15 more
wiley +1 more source
Pharmacy‐Based Immunization Delivery: A Comprehensive History and Current Challenges
ABSTRACT Pharmacists and their teams have a long history of involvement with vaccines. This paper describes the contributions of pharmacy‐based immunization delivery in the United States from the 1800's to date. Early activities centered around storage and distribution of antitoxins and vaccines. From the 1950s through the early 1990s, pharmacists were
Jean‐Venable R. Goode +4 more
wiley +1 more source
A Single Intradermal Injection of Autologous Adipose-Tissue-Derived Stem Cells Rejuvenates Aged Skin and Sharpens Double Eyelids. [PDF]
Ichihashi M +8 more
europepmc +1 more source
Different therapeutic modalities in a patient with multiple spontaneously developed keloids: a case report [PDF]
Keloids are benign tumors that usually develop as an excessive healing response to injury. They remain a challenging therapeutic problem to this day. Numerous treatment approaches are available, yet therapeutic results are often not satisfactory.
Bukvić-Mokos, Zrinka +2 more
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Alternate Light Source (ALS) Detection Does Not Confirm Occult Bruises
Visible light spectrum. ABSTRACT Almost all victims of assault and strangulation who seek medical care receive their initial medical care in the emergency department (ED), and many patients are referred to forensic nurses during or immediately after the ED evaluation.
William Hauda II +5 more
wiley +1 more source
Induction of IL‐9‐producing CD8+ T cells by ascochlorin derivatives
A newly synthesised ascochlorin derivative, N184, induces small amounts of IL‐9‐producing CD8+ T cells. N184 improved the survival of CD8+ T cells and enhanced their antitumour activity, partially in an IL‐9‐dependent manner. The antitumour effect was completely dependent on IFNγ secretion rather than the cytotoxic activity of CD8+ T cells.
Natsumi Imano +5 more
wiley +1 more source

