Results 61 to 70 of about 2,705,948 (213)
United European Gastroenterology Journal, EarlyView.ABSTRACT Malabsorption is a complex and multifaceted condition characterised by the defective passage of nutrients into the blood and lymphatic streams. Several congenital or acquired disorders may cause either selective or global malabsorption in both children and adults, such as cystic fibrosis, exocrine pancreatic insufficiency (EPI), coeliac ...
Marco Vincenzo Lenti +29 more
wiley +1 more source
World Journal of Surgery, EarlyView.Fatty pancreas was pathologically assessed and quatificated using tumor and non‐tumor portions of resected specimens in patients with pancreatic cancer. We found that the presence of fatty pancreas evaluated in non‐tumor portions was an independent inferior prognostic indicator for overall survival and recurrence free survival.
Yasunari Fukuda +9 more
wiley +1 more source
REMEDI: REinforcement learning-driven adaptive MEtabolism modeling of primary sclerosing cholangitis DIsease progression [PDF]
arXiv, 2023 Primary sclerosing cholangitis (PSC) is a rare disease wherein altered bile acid metabolism contributes to sustained liver injury. This paper introduces REMEDI, a framework that captures bile acid dynamics and the body's adaptive response during PSC progression that can assist in exploring treatments.
arxiv
postulating a common tumor entity [PDF]
, 2016 The set definition of distal cholangiocarcinomas and adenocarcinomas of the pancreatic head is challenged by their close anatomical relation, similar growth pattern, and corresponding therapeutic outcome. They show a mutual development during embryologic
Bahra, Marcus +4 more
core +1 more source
Invasive intraductal papillary mucinous neoplasm and pancreatic ductal adenocarcinoma : a comparison in clinicopathology and long-term outcome [PDF]
, 2022 Background: The resections for both pre-malignant and invasive intraductal papillary mucinous neoplasm (inv-IPMN) have increased the last decades. Long term outcome, and the impact of adjuvant chemotherapy, non-regional lymph node status and recurrence ...
Holmberg, Marcus
core +1 more source
Cytoplasmic Vacuolization: A Fascinating Morphological Alteration From Cellular Stress to Cell Death
Cancer Science, EarlyView.This review provides a thorough examination of contemporary studies on cytoplasmic vacuolization in mammalian cells, elucidating its etiology, origins, and molecular pathways. Additionally, it highlights the potential of CVACD as an innovative therapeutic strategy for cancer.
Xiaoxu Wen, Hongru Ma
wiley +1 more source
Physiologically-Based Pharmacokinetic Modeling of Blood Clearance of Liver Fluorescent Markers for the Assessment of the Degree of Hepatic Ischemia-Reperfusion Injury [PDF]
arXiv, 2023 During liver transplantation, ischemia-reperfusion injury (IRI) is inevitable and decreases the overall success of the surgery. While guidelines exist, there is no reliable way to quantitatively assess the degree of IRI present in the liver. Our recent study has shown a correlation between the bile-to-plasma ratio of FDA-approved sodium fluorescein (SF)
arxiv
Oncotarget, 2017 Intraductal papillary neoplasm of the bile duct (IPNB) has been widely recognized. However, the knowledge of intracystic papillary neoplasm of the gallbladder (IPNG) including papillary adenoma and adenocarcinoma is not well defined. In this study, we compared the clinicopathological and immunohistochemical features between 32 IPNG cases and 32 IPNB ...
Yuan Xie +14 more
openaire +4 more sources
A case of intraductal tubulopapillary neoplasm of the pancreas originating from the branch duct: cast in the mold sign [PDF]
, 2021 A 59-year-old man with jaundice and lower common bile duct stenosis was referred to our institution for diagnosis and treatment. Computed tomography and magnetic resonance imaging showed a well-circumscribed smoothly marginated solid mass lesion in the ...
Horiguchi, Ryota +6 more
core
Cancer Science, EarlyView.This study analyzed 1356 cases using GenMineTOP, Japan's first dual DNA–RNA CGP test, and identified oncogenic alterations in 91.5% of cases. The RNA panel detected 105 fusion events, including 11 NTRK fusions. Furthermore, the analysis clarified the independent effects of genomic abnormalities and cancer type on RNA expression, providing valuable ...
Kousuke Watanabe +7 more
wiley +1 more source