Results 81 to 90 of about 54,792 (216)

The emerging role of the Hippo signaling pathway in interorgan crosstalk

The FEBS Journal, EarlyView.
Hippo signaling functions as a central hub of interorgan communication. Systemic cues from the gut, adipose tissue, and skeletal muscle—including hormones, metabolites, and microbial signals—regulate YAP/TAZ activity in a tissue‐ and context‐dependent manner.
Gahyeon Song, Chaerin Lee, Eek‐hoon Jho   +2 more
wiley   +1 more source

Prevalence and Correlation of Margin Status and Residual Disease in Subsequent Hysterectomized Specimens Following Loop Electrosurgical Excision Procedure (LEEP)

Thai Journal of Obstetrics and Gynaecology, 2012
Objectives: To evaluate the prevalence of residual disease in the subsequent hysterectomy specimens after loop electrosurgical excision procedure (LEEP) and its correlation with adequacy of margins in the previous specimens.Materials and ...
Suwanna Sornwanee
doaj  

Unveiling the molecular profile of adenosquamous gallbladder carcinoma: characterization of a Caucasian cohort

Histopathology, EarlyView.
GBASCs are MMRp tumours, exhibiting minimal HER2 overexpression and elevated PD‐L1 expression compared to adenocarcinomas. Especially in metastatic and TP53‐wild type tumours, GBASCs can express CLDN18, albeit limited to the glandular component. Their genomic profile resembles that of adenocarcinomas with an enrichment in alterations on PIK3CA, PTEN ...
Jessica Gasparello, Valentina Angerilli, Mario Domenico Rizzato, Edoardo Maffii, Carlotta Ceccon, Matilde Callegarin, Marianna Sabbadin, Monia Niero, Luisa Toffolatti, Francesca Bergamo, Paola Parente, Luca Mastracci, Federica Grillo, Alessandro Vanoli, Paola Mattiolo, Claudio Luchini, Angelo Paolo Dei Tos, Umberto Cillo, Giacomo Zanus, Sara Lonardi, Matteo Fassan   +20 more
wiley   +1 more source

Serous endometrial intraepithelial carcinoma: a case report. [PDF]

Pan Afr Med J, 2023
Najioui Y, Karich N, Haloui A, Miry A, Bennani A.   +4 more
europepmc   +1 more source

Spatial transcriptomics reveals clonal relationships between intraductal carcinoma and adjacent invasive prostate cancer

Histopathology, EarlyView.
Spatial transcriptomics of six prostate samples reveals a close clonal relationship between high‐grade Prostatic Intraepithelial Neoplasia (HGPIN), Intraductal carcinoma (IDC) and adjacent invasive glands. In three samples, adjacent invasive glands had more copy number variants than HGPIN and IDC. Adjacent invasive glands were also placed at the end of
Hridya Harikumar, Myrthe de Waard‐van Baardwijk, Marit de Haan, Gregory van Beek, Karishma Lila, Martin E van Royen, Thierry PP van den Bosch, Mathijs A Sanders, Eric Bindels, Andrew Stubbs, Geert JLH van Leenders   +10 more
wiley   +1 more source

When to consider an inborn error of immunity: clues for physicians

Internal Medicine Journal, EarlyView.
Abstract The term inborn errors of immunity (IEIs) refers to the rapidly expanding group of genetic disorders causing dysregulation of the immune system. With improved genetic testing in recent years, the number of defined IEIs and their range of phenotypic presentations has grown vastly, with more than 550 IEIs now described.
Meera Thangarajah, Lucinda J. Berglund
wiley   +1 more source

Educational Case: Serous endometrial intraepithelial carcinoma and endometrial cancer. [PDF]

Acad Pathol, 2023
McGary CT, Boyum R.
europepmc   +1 more source

Management of Non‐Plaque‐Induced Gingival Conditions: A Systematic Review—Part 2: Inflammatory and Immune Conditions; Neoplasms; and Gingival Pigmentation

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aims This systematic review assesses current evidence on the management of non‐plaque (dental biofilm)‐induced gingival diseases and conditions (NPIGDs), including (i) inflammatory and immune conditions, (ii) neoplasms and (iii) gingival pigmentations.
Maria Clotilde Carra, Cecile Wasielewski, Bruno Špiljak, Maja Sabalić‐Schoener, Sebastien Jungo, Ivan Alajbeg   +5 more
wiley   +1 more source

Electrocautery ablation therapy for anal intraepithelial carcinoma: A study protocol. [PDF]

Medicine (Baltimore), 2022
Ando N, Mizushima D, Takano M, Kitamura H, Shiojiri D, Nakamoto T, Aoki T, Watanabe K, Uemura H, Gatanaga H, Oka S.   +10 more
europepmc   +1 more source

Squamous Odontogenic Tumor: A Systematic Review

Oral Diseases, EarlyView.
ABSTRACT Objective Squamous odontogenic tumor is a rare benign epithelial odontogenic neoplasm whose overlapping features with other odontogenic lesions may hinder diagnosis and management. This systematic review analyzed clinical, radiographic, histopathological characteristics and treatment outcomes of SOT.
Paula Sousa Lopes de Cascaes, Licia Pacheco Teixeira, Andresa Borges Soares, Izabel Regina Fischer Rubira‐Bullen, Monikelly Carmo Narchini do Nascimento, José Luiz Cintra Junqueira, Mariana Quirino Silveira Soares   +6 more
wiley   +1 more source