Results 91 to 100 of about 99,638 (285)

Single‐cell RNA sequencing revealed the T‐cell heterogeneity and exhaustion subsets of Helicobacter pylori‐induced gastritis‐to‐cancer transformation

VIEW, EarlyView.
H. pylori infection is a major cause of stomach cancer, but its effect on immune cells in tumors is unclear. Using single‐cell sequencing, we mapped the stomach tumor environment and discovered a specific exhausted T‐cell subtype, marked by the FYB1 gene, that is abundant in H. pylori‐positive tumors and linked to patient prognosis. Our findings reveal
Yanhui Yang, Yanxia Liu, Xiaole Guo, Zhaorun Li, Ziyu Liu, Shuming Zhang, Yuma Yang, Jun Liu, Shoucheng Ma, Linke Ma, Xianmei Chen, Xue Li, Yuanyuan Tang, Xiaoling Ding, Xiaofei Li, Qian Hao, Yanjie You, Tingting Yang, Qingrui Li, Xue Zhang, Sihan Zhang, Hengjun Gao, Shengjuan Hu   +22 more
wiley   +1 more source

Colposcopy in diagnosis and treatment of cervical intraepithelial neoplasia (CIN) [PDF]

, 1987
AIMS OF THE STUDIES 1. To investigate the diagnostic value of colposcopy under research conditions, in patients with an indication for colposcopy. (Wouter M. Huisman) 2.
Huisman, W.M. (Wouter), Wijnen, J.A. (Hans)   +1 more
core   +7 more sources

Dynamics of genotype-specific HPV clearance and reinfection in rural Ghana may compromise HPV screening approaches [PDF]

, 2019
Persistent Human Papillomavirus (HPV) infection is a prerequisite for cervical cancer development. Few studies investigated clearance of high-risk HPV in low-and-middle-income countries.
Adams, Rashid A., Adunyame, Lois, Amuah, Joseph E., Asmah, Richard H., Boateng, Gifty, Dunyo, Priscilla, Gedzah, Isaac, Hansen, Benjamin T., Kaufmann, Andreas M., Krings, Amrei, Nkansah, Dinah O., Wiredu, Edwin K., Wormenor, Comfort M.   +12 more
core   +1 more source

Combined Transcriptomic and Proteomic Forecast Analyses for Potential Biomarkers of Smoking‐Induced Benign and Malignant Transformation of Vocal Fold Lesions

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Laryngeal dysplasia and Reinke's edema (RE) are common vocal fold lesions associated with smoking. While the former is cancer prone, most cases of the latter do not undergo malignant transformation. Therefore, we proposed identifying biomarkers of smoking‐induced benign‐malignant transformation of vocal fold lesions.
Yun‐Yi Liu, Pei‐Yun Zhuang
wiley   +1 more source

Distribution of human papillomaviruses and bacterial vaginosis in HIV positive women with abnormal cytology in Mombasa, Kenya [PDF]

, 2016
Background: HPV is the major etiological factor in the causal pathway for cervical cancer, which is the leading cancer among women in sub-Saharan Africa. HIV is associated with a higher prevalence and a broader range of high-risk HPV genotypes.
Harebottle, Ronald, Mabeya, Hillary, Menon, Sonia, Rossi, Rodolfo, Vanden Broeck, Davy   +4 more
core   +2 more sources

DNA‐Methylation for Risk‐Stratification of Women Without a Fully Visible Transformation Zone at Colposcopy: A Cross‐Sectional Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To evaluate the performance of DNA methylation markers for the detection of cervical precancer among screening‐positive older women without a fully visible transformation zone at colposcopy (TZ3). Design Cross‐sectional study. Setting Colposcopy clinics, Central Denmark Region, 2019–2021.
Karen Omann Binderup, Joachim Boers, Line Winther Gustafson, Berit Andersen, Lone Kjeld Petersen, Pinar Bor, Joost Gribnau, Wim G. V. Quint, Henk Van Den Munckhof, Mette Tranberg, Anne Hammer   +10 more
wiley   +1 more source

Efficacy in treatment of subclinical cervical HPV infection without intraepithelial neoplasia: systematic review

São Paulo Medical Journal, 2000
CONTEXT: The treatment of the subclinical Human papillomavirus (HPV) infection of the uterine cervix is controversial. OBJECTIVE: To assess the efficacy of any therapy for subclinical HPV infection of the cervix without intraepithelial neoplasia, via a ...
Fábio Russomano, Aldo Reis, Maria José de Camargo, Maria Virgínia Peixoto Dutra, Sandra Costa Fonseca, Jean Anderson   +5 more
doaj   +1 more source

Prevalence of human papillomavirus genotypes in women with normal and abnormal cervical cytology in Iran [PDF]

, 2006
Introduction: HPV infection has a prime etiologic role in development and progression of cervical cancer, one of the most frequent forms of cancer among women in developing countries.
Dastan, J., Ensani, F., Ghaffari, S.R., Mohagheghi, M.A., Mollahajian, H., Moradi, A., Mousavi-Jarrahi, A., Ramezanzadeh, F., Sabokbar, T., Yarandi, F.   +9 more
core  

HPV vaccination of immunocompromised hosts. [PDF]

, 2017
It is well-established that immunocompromised people are at increased risk of HPV-related disease compared with those who are immunocompetent. Prophylactic HPV sub-unit vaccines are safe and immunogenic in immunocompromised people and it is strongly ...
Bhatla, N, Brotherton, JML, de Sanjosé, S, Garland, SM, IPVS, Kaufmann, AM, Moscicki, AB, Palefsky, JM, Sankaranarayanan, R, Stanley, M   +9 more
core   +3 more sources

SOX1/PAX1 Methylation for Triage of HPV‐Positive Women in Cervical Cancer Screening: A Cohort Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To establish a better triage strategy using SOX1/PAX1 methylation detection for high‐risk HPV (hrHPV)‐positive women than cytology. Design A cohort study. Setting Population‐based cervical cancer (CC) screening cohort. Population A total of 5684 women were enrolled.
Hongyu Xie, Junyan Li, Huiru Huang, Ansong Emmanuel, Hui Wang, Weiguo Lu, Xiao Li   +6 more
wiley   +1 more source