Results 141 to 150 of about 130,124 (257)
De‐escalating radical surgery for select FIGO Stage I cervical cancer
Abstract Four recent prospective trials demonstrated that de‐escalation of radical surgery for select patients with apparent low‐risk, FIGO Stage I cervical cancer does not compromise cancer‐related survival but does improve quality of life and provide the opportunity to preserve fertility.
Sara Moufarrij +5 more
wiley +1 more source
SLC3A1 Mitigates Ferroptosis and Promotes Enzalutamide Resistance in Prostate Cancer
SLC3A1 is a promising therapeutic target for advanced prostate cancer. ABSTRACT Prostate cancer (PCa) remains a leading cause of cancer‐related mortality in aging male, with resistance to enzalutamide (Enza) representing a major therapeutic challenge. This study identifies SLC3A1 as a key driver of Enza resistance.
Peng Liu +5 more
wiley +1 more source
Prevention of Myc‐Driven Prostate Cancer in Mice by Oral Administration of Sulforaphane
ABSTRACT Prevention is desirable to reduce suffering and death from prostate cancer. However, a clinical‐grade intervention for the prevention of this malignancy is still lacking. This study was undertaken to determine the feasibility of prostate cancer prevention by broccoli constituent sulforaphane (SFN) because epidemiological studies have suggested
Krishna B. Singh +3 more
wiley +1 more source
Penile intraepithelial neoplasia: results of photodynamic therapy
Failure of response to treatment or recurrent disease is often noted in patients with penile intraepithelial neoplasia. Photodynamic therapy has recently been added to the list of treatment modalities used for this diagnosis. Our primary objective was to
Paoli, John, +5 more
core
Metabolism in Tumor: Mechanisms and Therapeutic Perspectives
Tumor metabolic reprogramming converges on three hubs—the SREBP1/2–FASN–SCD1 lipogenic axis, the HIF‐1α–GLUT1–LDHA glycolytic axis, and the LDLR–SCARB1–LXR cholesterol system—which integrate transcriptional, epigenetic (histone lactylation, m6A), and microenvironmental inputs to generate metabolic plasticity, immune evasion, and therapy resistance ...
Jia‐Chen Cheng +6 more
wiley +1 more source
Prostate Cancer Development, Progression, and Therapy
This review provides an integrated overview of prostate cancer development, progression, and therapy, spanning historical milestones, molecular mechanisms, advanced research models, and emerging therapeutic strategies. It highlights recent advances in precision diagnosis, lineage plasticity, therapy resistance, and next‐generation treatments for ...
Xin Jin +9 more
wiley +1 more source
Efeito da cirurgia de alta freqüência no tecido de revestimento do colo uterino. [PDF]
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Departamento de Tocoginecologia, Curso de Medicina, Florianópolis ...
Oliveira, Daniel May de
core
Abstract Gastrointestinal cancer is a global health problem. In the new 6th edition of the World Health Organization Classification of Tumours (WCT) of the Digestive System, updated evidence and guidance is provided for the aetiology, pathogenesis, diagnosis, classification, grading, staging and prognosis of these tumours.
Iris D Nagtegaal +5 more
wiley +1 more source
Exfoliative cytology as a tool in the preinvasive anal lesions diagnosis
The anal cancer increase in high-risk populations stimulates the implementation of protocols to carry out early diagnosis, as well as the monitoring of high-grade anal intraepithelial neoplasia as a precursor lesion.
Javier Martínez Navarro
doaj
Comparison of Cervical Screening at 6‐ and 12‐Weeks Postnatal: A Paired‐Sample Feasibility Study
ABSTRACT Objective Feasibility of a paired‐sample study comparing cervical screening and urine self‐sampling at 6‐ and 12‐weeks postnatal. Design Paired‐sample feasibility study. Setting Acute hospital. Population or Sample Females within 6 weeks of childbirth. Methods Paired‐sample study comparing cervical screening and high‐risk human papillomavirus (
Victoria A. Cullimore +15 more
wiley +1 more source

