Results 101 to 110 of about 144,436 (251)

Delivery mode and maternal health conditions before and after childbirth: A population‐based cohort study from Estonia

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Cesarean section is associated with higher rates of chronic health conditions and pregnancy‐related complications, whereas vaginal delivery is more commonly linked to pelvic floor and perineal complications. These findings emphasize the need for individualized decision‐making and thorough counseling about the risks and benefits of each delivery method.
Katrin Täär, Helle Karro, Merli Saare, Reedik Mägi, Estonian Biobank Research Team, Andres Metspalu, Lili Milani, Tõnu Esko, Mait Metspalu, Mari Nelis, Georgi Hudjashov, Andres Salumets, Triin Laisk, Maire Peters   +13 more
wiley   +1 more source

Targeting KRAS for cancer therapy

British Journal of Pharmacology, EarlyView.
In recent years, therapeutics targeted against KRAS proto‐oncogene GTPase (KRAS)‐mutant cancers have seen significant progress. Herein we outline the biology and epidemiology of KRAS alterations at the lineage and allele levels, reviewing the clinical evidence for KRASG12C inhibition from the discovery of the recessive switch pocket to sotorasib ...
Jianlong Jia, Ruonan Liu, Tonia A. Adamide, Isis E. Fernandez, Georgios T. Stathopoulos   +4 more
wiley   +1 more source

Screening for cervical intraepithelial neoplasia [PDF]

BMJ, 1994
EDITOR, - J Elizabeth Macgregor and colleagues show that the incidence of invasive cervical cancer fell sharply in women aged 40-69 who had been well screened and had had the opportunity of repeat screening.1 Screening was associated with a tendency to present at an earlier stage.
openaire   +2 more sources

Clinical Significance of a Cell‐Of‐Origin‐Based Classification in Pancreatic Ductal Adenocarcinoma

Cancer Science, EarlyView.
Schematic overview of a cell‐of‐origin‐based classification of pancreatic ductal adenocarcinoma (PDAC), highlighting distinct biological features and therapeutic implications of Acinar‐ and Ductal‐subtypes. ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal malignancies, with limited therapeutic options and poor clinical ...
Tatsuya Kikuchi, Soichiro Ako, Hironari Kato, Hideaki Kinugasa, Masaki Uchida, Takashi Oda, Ryosuke Hirai, Akihiro Matsumi, Kazuya Miyamoto, Hiroyuki Terasawa, Yuki Fujii, Daisuke Uchida, Kazuyuki Matsumoto, Koichiro Tsutsumi, Shigeru Horiguchi, Kazuya Yasui, Tomokazu Fuji, Kosei Takagi, Hirokazu Kato, Tomoyuki Honda, Fumio Otsuka, Motoyuki Otsuka   +21 more
wiley   +1 more source

Use of topical imiquimod in the treatment of VIN: a case report and review of the literature

International Journal of Women's Dermatology, 2016
Vulvar intraepithelial neoplasia (VIN) is a premalignant disease of the vulvar squamous epithelium. Standard treatment for VIN lesions is surgical excision.
Chelsea Grimes, BS, MS, Cheri Cunningham, BS, Michael Lee, MD, Andrea Murina, MD   +3 more
doaj   +1 more source

Cervical intraepithelial neoplasia grade 2 across continents.

, 2014
Cervical intraepithelial neoplasia grade 2 across continents.
Apple C. M. Yeung (626923), Martin C. S. Wong (288769), Wendy C. S. Ho (630581), Josette S. Y. Chor (630582), Mamie Hui (630583), Paul K. S. Chan (271343), Martin C. W. Chan (341911)   +6 more
core   +1 more source

HPV42 – a human papillomavirus classified as a low‐risk type with oncogenic potential

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Human papillomavirus (HPV) type 42 is a rare HPV type currently classified as “low‐risk” and belongs to the alpha genus. It has primarily been detected in benign vulvar papillomas and is predominantly associated with benign lesions such as anogenital warts.
Sven Niklas Burmann, Ulrike Wieland, Steffi Silling, Frank Oellig, David Chromy, Julia Hyun, Thilo Gambichler, Alexander Kreuter   +7 more
wiley   +1 more source

Expression of the stem cell markers NANOG and SOX2 in the cervical squamous carcinogenesis

Radiology and Oncology
The aim of the present study was to assess a diagnostic potential of stem cell markers NANOG and SOX2 for classifying cervical squamous intraepithelial lesions (SILs)/cervical intraepithelial neoplasia (CIN).
Koren Miha, Zlajpah Margareta, Poljak Mario, Komlos Kristina Fujs, Flezar Margareta Strojan   +4 more
doaj   +1 more source

Treatment of anal intraepithelial neoplasia

Journal of British Surgery, 1994
Abstract The natural history and malignant potential of anal intraepithelial neoplasia (AIN) remain uncertain, making management decisions about such lesions difficult. The management of 70 patients with AIN is described. The majority of lesions encountered were low grade (AIN I and II; 43 of 70) and required no treatment, but eight ...
J H, Scholefield, O A, Ogunbiyi, J H, Smith, K, Rogers, F, Sharp   +4 more
openaire   +2 more sources

Scalp Dysesthesia: Emerging Pathophysiologic Insights and Therapeutic Implications

International Journal of Dermatology, EarlyView.
Scalp dysesthesia is a chronic condition diagnosed through exclusion. This scoping review synthesized data from 59 patients to identify recurrent clinical features, comorbidities, and management strategies that may support earlier diagnosis. Emerging patterns suggest that neuronal sensitization may underlie common symptoms.
Aditya K. Gupta, Jaspreet Kaur, Amanda Liddy, Paradi Mirmirani, Vincent Piguet   +4 more
wiley   +1 more source