Results 71 to 80 of about 51,047 (183)

Apo10 and TKTL1 as novel liquid biopsy biomarkers for early detection of gastrointestinal malignancies

VIEW, EarlyView.
(A) Overview of the study population and schematic illustration showing tumor‐derived apoptotic and metabolic biomarkers, Apo10 and TKTL1, being phagocytosed by circulating monocytes and subsequently detected in peripheral blood. (B) Illustration of the epitope detection in monocytes (EDIM) strategy, using a flow‐cytometric gating approach based on ...
Zhiying Mao, Qiyu Huang, Juan Xiao, Ziyu Liu, Xinyan Zou, Yuying Liu, Lizhi Liu, Musheng Zeng, Chuanbo Xie   +8 more
wiley   +1 more source

Prognostic Value of KI6 Biomarker to Predict Short Term Prognosis of Low Grade Cervical Intraepithelial Neoplasia in Human Papilloma Virus Negative and Positive Patients

Middle East Journal of Cancer, 2019
Background: Cervical cancer is the most common gynecologic cancer in developing countries. Although this malignancy is preventable, problems exist with screening this cancer. Numerous studies have researched immunohistochemistry methods, such as the KI-
Leila Mousavi Seresht, Noorieh Sharifi, Mona Najafi, Helena Azimi, Nooshin Babapour, Zohreh Yousefi, Nazanin Beheshtian, Yasaman Nikooiyan   +7 more
doaj  

DNA‐Methylation for Risk‐Stratification of Women Without a Fully Visible Transformation Zone at Colposcopy: A Cross‐Sectional Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To evaluate the performance of DNA methylation markers for the detection of cervical precancer among screening‐positive older women without a fully visible transformation zone at colposcopy (TZ3). Design Cross‐sectional study. Setting Colposcopy clinics, Central Denmark Region, 2019–2021.
Karen Omann Binderup, Joachim Boers, Line Winther Gustafson, Berit Andersen, Lone Kjeld Petersen, Pinar Bor, Joost Gribnau, Wim G. V. Quint, Henk Van Den Munckhof, Mette Tranberg, Anne Hammer   +10 more
wiley   +1 more source

PROSTATIC INTRAEPITHELIAL NEOPLASIA: CLINI

Urology Research and Practice, 2019
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A.U. ÖNDER, O. ARAR, A. ÇİFTCİ, Ö. YAYCIOĞLU, V. Yalçın, V. SOLOK   +5 more
doaj   +2 more sources

Comparison of Cervical Screening at 6‐ and 12‐Weeks Postnatal: A Paired‐Sample Feasibility Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective Feasibility of a paired‐sample study comparing cervical screening and urine self‐sampling at 6‐ and 12‐weeks postnatal. Design Paired‐sample feasibility study. Setting Acute hospital. Population or Sample Females within 6 weeks of childbirth. Methods Paired‐sample study comparing cervical screening and high‐risk human papillomavirus (
Victoria A. Cullimore, Tessa Dean, Kim Chu, Adam Brentnall, Karin Denton, Katherine Hunt, Alexandra Sargent, Laura Johns, Katharine Edey, Sarah L. Coleridge, Jane Borley, Rebecca Newhouse, Holly Baker‐Rand, Lorna McWilliams, Emma J. Davidson, Jo Morrison   +15 more
wiley   +1 more source

Testicular Biopsies in Adolescent and Adult Andrological Patients: The EAA Clinical Guidelines

Andrology, EarlyView.
ABSTRACT Background Histological evaluation of testicular tissue is central to the assessment of infertile men, particularly those at an increased risk of testicular germ cell tumors (TGCT). Traditionally, testicular biopsies have been used primarily for diagnostic purposes, such as the detection of germ cell neoplasia in situ (GCNIS). With advances in
Lise Aksglaede, George Kanakis, Ewa Rajpert‐De Meyts, Davor Jezek, Ferran Algaba, Gert Dohle, Jolanta Slowikowska‐Hilczer, Sabine Kliesch, Hermann M. Behre, Csilla Krausz, Dimitrios G. Goulis, Niels Jørgensen   +11 more
wiley   +1 more source

Efficacy and Safety of Anal High‐Grade Squamous Intraepithelial Lesion Treatment Modalities: A Systematic Review

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background There is compelling evidence that treating high‐grade squamous intraepithelial lesions (HSIL), the anal squamous cell cancer (ASCC) precursor, reduces the risk of developing ASCC. Using high‐resolution anoscopy (HRA), surgical excision, ablative and topical therapies are widely used to treat HSIL.
Matthew Joseph Marino, Sophie Jones, Nicholas Reid Caldwell, Catherine Cartwright, Benedict Blacket, Richard Clive Turner   +5 more
wiley   +1 more source

Balancing diagnostic accuracy and cost in the follow‐up of histological low‐grade squamous intraepithelial lesions

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Primary follow‐up of histological LSIL can shift from colposcopy to liquid‐based co‐testing without missed cancers, as the incremental cost per additional HSIL+ detected is unjustified. Abstract Introduction Primary cervical screening with testing for human papillomavirus (HPV) brings increased detection of women with low‐grade squamous intraepithelial
Riina Aarnio, Vasudha Ahuja, Linda Ryen, Lovisa Bergengren   +3 more
wiley   +1 more source

Use of topical imiquimod in the treatment of VIN: a case report and review of the literature

International Journal of Women's Dermatology, 2016
Vulvar intraepithelial neoplasia (VIN) is a premalignant disease of the vulvar squamous epithelium. Standard treatment for VIN lesions is surgical excision.
Chelsea Grimes, BS, MS, Cheri Cunningham, BS, Michael Lee, MD, Andrea Murina, MD   +3 more
doaj   +1 more source

Human papillomavirus persistence and clearance in women living with HIV: A five‐year retrospective analysis from an Italian university center

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
In women living with HIV, HPV clearance occurred after a mean of approximately 2 years under antiretroviral therapy. Baseline positivity for the high‐risk HPV pool was associated with delayed clearance, suggesting that HPV genotype may influence viral persistence more than immunovirological status in clinically stable patients.
Annunziata Carlea, Dario Colacurci, Giorgia D'Apice, Laura Letizia Mazzarelli, Massimiliano Pellicano, Luigi Falco, Ginevra Sepe, Oriana Imperatore, Giuseppe Maria Maruotti, Maurizio Guida, Laura Sarno   +10 more
wiley   +1 more source