Results 31 to 40 of about 124,012 (138)
The Lord of the Rings: Cysteine bonds crosslink the tail of siphovirus
Abstract Long, non‐contractile tails composed of helical hexameric protein repeats that assemble into continuous tubular structures characterize siphoviruses. The siphovirus tail tube protein gp39 contains two cysteine residues per monomer. Cryo‐electron microscopy revealed that these cysteines are oriented toward the interface between the rings, which
Simona Povilonienė +9 more
wiley +1 more source
Modelo de catálise enzimática: síntese e ciclização intramolecular de 2-(2-Bromoetoxi)-3-Alquilfenóis [PDF]
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas. Programa de Pós-Graduação em Química.Os compostos 2-(2-bromoetoxi)-3-alquilfenóis (alquil = metil, isopropil, sec-butil e terc-butil) foram sintetizados ...
Martendal, Adriano
core
Enzyme@Silicone: A Versatile Combo for Robust Synthetic Biocatalysis?
Silicone‐based polymers are versatile materials for enzyme immobilization, offering unique advantages such as chemical inertness, thermal stability, and tunable morphology. This review highlights their applications in synthetic biocatalysis, from batch to continuous processes, and addresses key challenges such as mass transport limitations and ...
Marion B. Ansorge‐Schumacher
wiley +1 more source
Estudo do mecanismo da reação entre glicina e aspirina [PDF]
TCC (graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Físicas e Matemáticas. Curso de Química.A presença da catálise básica geral nos sistemas biológicos é importante para que uma série de reações, por exemplo as reações ...
CAON, Natália Bruzamarello
core
Natural product flavonoids have a multi‐target therapeutic intervention effect on osteoarthritis. They promote autophagy and cartilage synthesis while alleviating oxidative stress, inhibiting inflammation, and inhibiting matrix degradation. By restoring OPG/RANKL balance and regulating bone metabolism, these compounds synergistically delay the ...
Haibin Wang +6 more
wiley +1 more source
Vitamin C is a widely used vitamin. Here we review the occurrence and properties of aldonolactone oxidoreductases, an important group of flavoenzymes responsible for the ultimate production of vitamin C and its analogs in animals, plants, and single-cell
Willem J. H. van Berkel +6 more
core +1 more source
Oxidoreductases in Glycoprotein Glycosylation, Folding, and ERAD
N-linked glycosylation and sugar chain processing, as well as disulfide bond formation, are among the most common post-translational protein modifications taking place in the endoplasmic reticulum (ER).
Gerardo Z. Lederkremer +3 more
core +1 more source
Reactive Oxygen Species in Breast Cancer: From Redox Dysregulation to ROS‐Responsive Therapeutics
ABSTRACT Breast cancer is the most frequently diagnosed malignancy among women worldwide, with 2.3 million new cases and approximately 670,000 deaths reported in 2022 alone. Despite advances in therapy, metastasis and acquired drug resistance remain major clinical challenges.
Marija Nikolovska +5 more
wiley +1 more source
Phytofabricated metal oxide nanoparticles may activate the Nrf2–Keap1 axis through a dual‐stimulus mechanism, coupling nanoparticle‐derived ROS with phytochemical‐mediated Keap1 modification, steering mesenchymal stem cells toward osteogenic commitment — a mechanistic framework this review consolidates from current evidence.
Muhammad Irfan +3 more
wiley +1 more source
The Protein Environment Restricts the Intramolecular Charge Transfer Character of the Luciferine/Luciferase Complex [PDF]
The elecronic characterization of the luciferine/luciferase complex is fundamental to tune its photophysical properties and develop more efficient devices based on this luminiscent system.
Henar, Mateo-delaFuente +3 more
core +1 more source

