Results 1 to 10 of about 6,403 (117)

Crystal Structure of an Intramolecular Mesaconyl-Coenzyme A Transferase From the 3-Hydroxypropionic Acid Cycle of Roseiflexus castenholzii [PDF]

Frontiers in Microbiology, 2022
Coenzyme A (CoA) transferases catalyze reversible transfer of CoA groups from CoA-thioesters to free acids, playing important roles in the metabolism of carboxylic acids in all organisms.
Zhenzhen Min, Xin Zhang, Wenping Wu, Yueyong Xin, Menghua Liu, Kangle Wang, Xingwei Zhang, Yun He, Chengpeng Fan, Zhiguo Wang, Xiaoling Xu, Xiaoling Xu, Xiaoling Xu   +12 more
doaj   +4 more sources

Open Biology: overview for special issue on dynamics of protein fatty acylation

Open Biology, 2021
Fatty acylation is a widespread form of protein modification that occurs on specific intracellular and secreted proteins. Beyond increasing hydrophobicity and the affinity of the modified protein for lipid bilayers, covalent attachment of a fatty acid ...
Marilyn D. Resh
doaj   +1 more source

Stereodivergent Intramolecular Cyclopropanation Enabled by Engineered Carbene Transferases [PDF]

Journal of the American Chemical Society, 2019
We report the development of engineered myoglobin biocatalysts for executing asymmetric intramolecular cyclopropanations resulting in cyclopropane-fused γ-lactones, which are key motifs found in many bioactive molecules. Using this strategy, a broad range of allyl diazoacetate substrates were efficiently cyclized in high yields with up to 99 ...
Ajay L. Chandgude, Xinkun Ren, Rudi Fasan   +2 more
openaire   +2 more sources

Identification of the Lyso-Form N -Acyl Intramolecular Transferase in Low-GC Firmicutes [PDF]

Journal of Bacteriology, 2017
ABSTRACT Bacterial lipoproteins are embedded in the cell membrane of both Gram-positive and Gram-negative bacteria, where they serve numerous functions central to cell envelope physiology. Lipoproteins are tethered to the membrane by an N -acyl- S -(mono/di)-acyl-glyceryl-cysteine ...
Krista M, Armbruster, Timothy C, Meredith   +1 more
openaire   +2 more sources

The two opposing activities of adenylyl transferase reside in distinct homologous domains, with intramolecular signal transduction [PDF]

The EMBO Journal, 1997
Adenylyl transferase (ATase) is the bifunctional effector enzyme in the nitrogen assimilation cascade that controls the activity of glutamine synthetase (GS) in Escherichia coli. This study addresses the question of whether the two antagonistic activities of ATase (adenylylation and deadenylylation) occur at the same or at different active sites.
R, Jaggi, W C, van Heeswijk, H V, Westerhoff, D L, Ollis, S G, Vasudevan   +4 more
openaire   +2 more sources

New Perspectives Related to the Bioluminescent System in Dinoflagellates: Pyrocystis lunula, a Case Study [PDF]

, 2020
Pyrocystis lunula is considered a model organism due to its bioluminescence capacity linked to circadian rhythms. The mechanisms underlying the bioluminescent phenomenon have been well characterized in dinoflagellates; however, there are still some ...
Costas, Benjamin, De Donato, Marcos, Fajardo Quiñones, Carlos, Fernández Acero, Francisco Javier, Mancera Romero, Juan Miguel, Martínez-Rodríguez, Gonzalo, Rodulfo, Hectorina   +6 more
core   +1 more source

The N-end rule pathway is a sensor of heme [PDF]

, 2008
The conjugation of arginine, by arginyl-transferase, to N-terminal aspartate, glutamate or oxidized cysteine is a part of the N-end rule pathway of protein degradation.
A. Varshavsky, Boon, Gilles-Gonzalez, H. Wang, Haas, Hu, Ishikawa, Kwon, Ma, Mogk, R.-G. Hu, Reinking, Rouault, Sasaki, Tasaki, Tasaki, Turner, Varshavsky, Veal, Yang, Z. Xia, Zhang   +21 more
core   +2 more sources

Structure of the Janus Protein Human CLIC2 [PDF]

, 2007
Chloride intracellular channel (CLIC) proteins possess the remarkable property of being able to convert from a water-soluble state to a membrane channel state.
Adams, J, Board, P, Breit, S, Brown, L, Coggan, M, Cromer, B, Curmi, P, Dulhunty, A, Gorman, M, Hansen, G, Littler, D, Mazzanti, M, Parker, M   +12 more
core   +1 more source

Modeling of the Aniline with Nitrobenzene Reaction by PM6 Method [PDF]

, 2006
Modeling of the aniline with nitrobenzene reaction was carried out by PM6 method with tetramethylammonium hydroxide. Calculated data prove that the stage of transfer of hydride ion from the p-[sigma]-complex to the acceptor, i.e.
T.A. Klimova, V.V. Bochkarev, L.S. Soroka, Stern, Orlov, Zheng Ya-Jun, Glukhovtsev, Fernandez, Danikiewicz, Ayyangar, Stern, Bartmess   +11 more
core   +1 more source

The Janthinobacterium sp. HH01 genome encodes a homologue of the V. cholerae CqsA and L. pneumophila LqsA autoinducer synthases [PDF]

, 2013
Janthinobacteria commonly form biofilms on eukaryotic hosts and are known to synthesize antibacterial and antifungal compounds. Janthinobacterium sp. HH01 was recently isolated from an aquatic environment and its genome sequence was established.
Blokesch, Melanie, Bode, Edna, Bode, Helge Björn, Bonge, Andreas, Daniel, Rolf, Dierking, Katja, Haack, Frederike Svenja, Hornung, Claudia, Jung, Kirsten, Krohn-Molt, Ines, Plener, Laure, Poehlein, Anja, Pohlen, Andrea, Pommerening-Röser, Andreas, Schmeißer, Christel, Schmidt, Martina, Schulenburg, Hinrich, Spieck, Eva, Streit, Wolfgang R., Timmermann, Gabriele, Utpatel, Christian   +20 more
core   +8 more sources