Intramolecular transferases - Open Access .click

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Intramolecular Accelerated Assembly of Molecular Beacons: A DNA Nanoarchitecture-based Spatial Confinement Strategy toward Terminal Deoxynucleotidyl Transferase Biosensing

Analytical Chemistry, 2023
Physiological function analysis of terminal deoxynucleotidyl transferase (TdT) in clinical medicine and hematopathology highlights its significance to be extensively utilized as a diagnostic biomarker for leukemia diagnosis. Herein, taking advantage of the spatial-confinement effect on a three-dimensional (3D) DNA nanoarchitecture, we reported a target-
Qi Wang +5 more
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Intramolecular Signal Transduction in Adenylyl Transferase May Coordinate the Opposing Activities of Two Distinct Domains

1998
Adenylyltransferase (ATase) is a bifunctional enzyme in the cascade control of glutamine synthetase (GS) in E. coli. ATase can catalyse either the adenylylation of GS or the de-adenylylation of GS-AMP, depending on the nitrogen status of the cell. The latter is sensed by the bifunctional enzyme uridylyltransferase (UTase) which relays the message via ...
R. Jaggi +4 more
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Intramolecular fluorescence enhancement: a continuous assay of Ras farnesyl:protein transferase