Obestatin signaling reactivates autophagy by NEDD4‐L activation under DMD conditions. Tyrosine switch on NEDD4‐L activates autoubiquitination that serves as a scaffold to recruit USP10 to form a deubiquitination complex, which stabilizes VPS34 to promote autophagy by activation of the Beclin1 complex. In parallel, NEDD4‐L favors AMPK exposure to CaMKKß
Icía Santos‐Zas +16 more
wiley +1 more source
Enzymatic processing of protein-based fibers [PDF]
Wool and silk are major protein fiber materials used by the textile industry. Fiber protein structure-function relationships are briefly described here, and the major enzymatic processing routes for textiles and other novel applications are deeply ...
A Anghileri +78 more
core +1 more source
Biosinteza, fermentacija, purifikacija i primjena surfaktina [PDF]
Surfactin, a bacterial cyclic lipopeptide, is produced by various strains of Bacillus subtilis and is primarily recognized as one of the most effective biosurfactants.
Nikhil S. Shaligram, Rekha S. Singhal
core +1 more source
Glutathione in Cancer Cell Death [PDF]
Glutathione (L-γ-glutamyl-L-cysteinyl-glycine; GSH) in cancer cells is particularly relevant in the regulation of carcinogenic mechanisms; sensitivity against cytotoxic drugs, ionizing radiations, and some cytokines; DNA synthesis; and cell proliferation
Ames +184 more
core +2 more sources
MSL-1 plays a central role in assembly of the MSL complex which mediates dosage compensation in Drosophila melanogaster : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Genetics at Massey University, Palmerston North, New Zealand [PDF]
Dosage compensation in Drosophila melanogaster is achieved by a twofold increase of transcription of X-linked genes in males. This involves the binding of four proteins, MSL-1, MSL-2, MSL-3 and MLE (collectively known as the MSLs) which are believed to ...
Pan, Lewis Li-Wei
core
A Structural Basis for Cellular Uptake of GST-Fold Proteins
It has recently emerged that glutathione transferase enzymes (GSTs) and other structurally related molecules can be translocated from the external medium into many different cell types.
Board, Philip G. +4 more
core +1 more source
Enzyme-catalyzed protein crosslinking [PDF]
The process of protein crosslinking comprises the chemical, enzymatic, or chemoenzymatic formation of new covalent bonds between polypeptides. This allows (1) the site-directed coupling of proteins with distinct properties and (2) the de novo assembly of
Faccio, Greta +3 more
core
Gas Phase Infrared Spectroscopy of Glycolipids
Carbohydrates and lipids are not only energy sources and structural components of cells but fulfill very diverse and important roles in a multitude of cellular processes. The combination of a carbohydrate and a lipid linked via a glycosidic bond yields a
Kirschbaum, C.
core
Molecular docking studies for the identification of novel melatoninergic inhibitors for acetylserotonin-O-methyltransferase using different docking ...
Er Azam, Sumra Wajid Abbasi, Syed Sik
core
Redox and proteolytic regulation of cardiomyocyte β1-adrenergic receptors - a novel paradigm for the regulation of catecholamine responsiveness in the heart. [PDF]
Steinberg SF.
europepmc +1 more source

