Vascular Calcification: Mechanisms, Models, and Therapies
ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu +5 more
wiley +1 more source
Effectiveness of Percutaneous Needle Electrolysis (PNE) and Intramuscular Electrical Stimulation (IMES) in the Management of Myofascial Pain Syndrome and Tendinopathies: A Systematic Review. [PDF]
Trybulski R +6 more
europepmc +1 more source
The developing bone was identified as an M2a‐like macrophage driven immune microenvironment with multidimensional developmental signatures. hME‐ApoEVs were successfully fabricated via stimulating the M2a‐like developing microenvironment in vitro and confirmed its recapitulation of developmental features.
Xiaoran Yu +11 more
wiley +1 more source
Irony of Iron Overload: Hereditary Hemochromatosis Complicated by Alcoholic Hepatitis, Gastrointestinal Bleeding, and Intramuscular Hematoma. [PDF]
Del Mundo HJF +4 more
europepmc +1 more source
ABSTRACT Neurotoxicity induced by excessive glutamatergic signaling is associated with synaptic dysfunction, calcium imbalance, and oxidative stress, which are key molecular events implicated in several neurodegenerative conditions. Monosodium glutamate (MSG), a common flavor enhancer, may exert neurotoxic effects, particularly on synaptic integrity ...
Medine Sibel Karagac +2 more
wiley +1 more source
Abstract Introduction Recognition and management of medical emergencies in dental practice is an essential topic area in dental education. However, limited published research on the topic is available from dental institutions in lower‐middle income countries (LMICs).
Kamran Ali +5 more
wiley +1 more source
Vitamin B12 deficiency: testing and treatment. [PDF]
Bedz D, Forsyth C.
europepmc +1 more source
Estimated impact of model‐guided venous thromboembolism prophylaxis versus real‐world practice
Abstract Background The American Society of Hematology (ASH) recommends assessing venous thromboembolism (VTE) and major bleeding risk to optimize pharmacological VTE prophylaxis for medical inpatients. However, the clinical utility of model‐guided approaches remains unknown.
Benjamin G Mittman, Michael B. Rothberg
wiley +1 more source
Pharmacokinetics of Lekethromycin in Swine Following Intramuscular Administration at Different Doses with a Single Intravenous Reference Dose for Absolute Bioavailability and Matrix Comparison. [PDF]
Wu Q +7 more
europepmc +1 more source
Abstract Background This study investigates the impact of disruptions in testosterone levels on bone remodeling, root resorption, and periodontal ligament (PDL) during orthodontic tooth movement (OTM) in a pubertal male rat model. Methods Testosterone deficiency was induced through orchiectomy, and the anabolic‐androgenic steroid (AAS, testosterone ...
Caio Luiz Bitencourt Reis +11 more
wiley +1 more source

