Results 221 to 230 of about 177,118 (275)

Precision mRNA Delivery via Ultrasound‐Controlled Release Perfluorocarbon Emulsions: An Innovative Ultrasound Theranostic Strategy with 19F MRI Feasibility

open access: yesSmall, EarlyView.
A key challenge in advancing messenger RNA (mRNA) therapeutics in cardiovascular diseases lies in achieving controlled release at the precise site within the vasculature. This study presents the development of perfluorocarbon nanodroplets with exceptional theranostic potential, enabling real‐time tracking through ultrasound and fluorine‐19 (19F ...
Haikun Liu   +14 more
wiley   +1 more source

An Integrated Method to Evaluate the Treatment Efficacy and Immunogenicity of B‐Cell Acute Lymphoblastic Leukemia Therapeutic Enzyme Formulations

open access: yesSmall Methods, EarlyView.
This work presents an integrated set of methods to evaluate the efficacy of asparaginase formulations against B‐cell Acute Lymphoblastic Leukemia (ALL) in mice, including the establishment of an ALL murine model, an amino acid depletion study using high‐performance liquid chromatography (HPLC), and comprehensive assessment of antibody production ...
Julien Santelli   +6 more
wiley   +1 more source

Effect of butorphanol in combination with xylazine during castration of calves: A randomised trial under field conditions

open access: yesVeterinary Record, EarlyView.
Abstract Background In horses, cats and dogs, the opioid butorphanol has been proven effective in management of visceral pain and for peri‐ and postoperative pain relief. The aim of this study was to evaluate physiological responses and indicators of noxious stimuli when adding butorphanol to xylazine for sedation of bull calves during surgical ...
Axel Sannö   +3 more
wiley   +1 more source

Survey of German veterinarians' approaches to pain assessment and management of perioperative pain in pet rabbits

open access: yesVeterinary Record, EarlyView.
Abstract Background This study aimed to assess veterinary practices in pain recognition and perioperative analgesic therapy in pet rabbits. Methods An online questionnaire was distributed German veterinarians from July to October 2022, containing questions on the frequency with which they treated rabbits and the methods they used to evaluate pain in ...
Stephanie Zein   +2 more
wiley   +1 more source

Cabotegravir + Rilpivirine Long-Acting: Overview of Injection Guidance, Injection Site Reactions, and Best Practices for Intramuscular Injection Administration. [PDF]

open access: yesOpen Forum Infect Dis
Teichner P   +19 more
europepmc   +1 more source

Neuromusculoskeletal ultrasound examination in Nicolau syndrome

open access: yes
PM&R, EarlyView.
Beytullah Yazar   +3 more
wiley   +1 more source

Effect of ‘combing’ on intramuscular sedation in pigs in a clinical setting—A randomised trial

open access: yesVeterinary Record, EarlyView.
Abstract Background Pigs pose distinct challenges to the anaesthetist due to their temperament, the limitations of manual restraint and species‐specific anatomical features. Despite the importance of minimising stress during clinical procedures, gentle handling techniques tailored for pigs in a clinical setting have yet to be clearly described or ...
Kaitlynn C. Ban   +5 more
wiley   +1 more source

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