Results 111 to 120 of about 61,446 (279)

Intramuscular Vitamin B12 Injections for Treating Chronic Low Back Pain

, 2014
Background: Low back pain is a common problem worldwide, but especially in westernized countries. It can often create a great financial burden to society due to people missing workdays or having work limitations.
Rooijakkers, Johanna M
core  

A phase 1 evaluation of inhaled oxytocin: Physiologically‐based pharmacokinetic model informed dosing of a novel heat‐stable oxytocin delivery system

British Journal of Clinical Pharmacology, EarlyView.
Aim To develop and validate a physiologically‐based pharmacokinetic (PBPK) model enabling inhaled oxytocin dose selection for clinical evaluation. Subsequently, to conduct a phase 1 study investigating the pharmacokinetics and safety of selected doses of an optimized inhaled oxytocin product in healthy, non‐pregnant female participants.
Pete Lambert, Carl M. J. Kirkpatrick, Rory Marriott, Siladitya Ray Chaudhuri, David Polidori, Bart Remmerie, Michelle P. McIntosh   +6 more
wiley   +1 more source

Nano‐networks via reaction‐induced self‐assembly coordinate spatiotemporal multi‐drug delivery for acute kidney injury therapy

BMEMat, EarlyView.
Multifunctional nano‐networks (NNWs) are prepared via reaction‐induced self‐assembly (RISA) of spermidine (SPD), epigallocatechin gallate (EGCG), 2‐formylphenylboronic acid (2‐FPBA), and deferoxamine (DFO) through dynamic iminoboronate bonds. These NNWs leverage the oxidative AKI microenvironment to trigger disintegration, enabling site‐specific ...
Juan Jin, Xiao Zhang, Chenxi Wang, Taian Jin, Xinyang Fang, Yixuan Gao, Mengchun Chen, Weiyang Meng, Chang Gao, Wenlu Li, Yuanfeng Li, Yijie Chen, Calvin A. Omolo, Thirumala Govender, Linqi Shi, Yunguang Wang, Yong Liu, Qiang He   +17 more
wiley   +1 more source

Administering intramuscular injections how does research translate into practice over time in the mental health setting? /

, 2015
Background: Increasingly, mental health nurses are expected to base their clinical practice on evidence based knowledge and many of the practice traditions that have passed between generations of nurses must now be examined within this scientific context.
Wynaden, Dianne, Sourinathan, Vijay., L Barr (9879686), J Tohotoa (9877568), Happell, B., O Al Omari (9877571), K Heslop (9877574), Heslop, Karen., Barr, Lesley., D Wynaden (9852572), Barr, L., Happell, Brenda., Helsop, Karen, Brenda Happell (9801788), Tohotoa, Jenny., Sourinathan, V., Sourinathan, Vijay, Heslop, Karen, Barr, Lesley, Al Omari, Omar, V Sourinathan (9879689), Wynaden, Dianne., Tohotoa, Jenny, HAPPELL, Brenda, Al Omari, Omar.   +24 more
core   +1 more source

Multifunctional hyaluronic acid hydrogel integrating exosome‐encapsulating gelatin microspheres accelerates skeletal muscle regeneration via TGF‐β1 activation and enhanced myogenic cell viability

BMEMat, EarlyView.
Schematic illustration of preparation of injectable H/G@Co@miR‐206 hydrogel for efficient skeletal muscle regeneration in cardiotoxin‐induced skeletal muscle injury SD rat model. Abstract The effective treatment of acute skeletal muscle injuries remains challenging, necessitating therapeutic strategies that concurrently reestablish vascular perfusion ...
Zhengzhe Han, Zongyue Li, Ang Li, Zheng Jiang, Saiyu Shi, Zhipeng Wang, Jishizhan Chen, Yun Qian, Yuanyang Gu, Xianyou Zheng   +9 more
wiley   +1 more source

Comparing the outcomes of in-vitro fertilization in patients receiving vaginal, subcutaneous, and intramuscular progesterone for luteal phase support: a three-armed randomized controlled trial

BMC Women's Health
Background The optimal approach to luteal-phase support in infertility treatment remains a subject of debate. This study was conducted to investigate the clinical outcomes, side effects, and patient satisfaction associated with vaginal, subcutaneous, and
Ensieh Shahrokh Tehraninejad, Sanaz Alizadeh, Elham Azimi Nekoo, Nikan Zargarzadeh, Mamak Shariat, Fedyeh Haghollahi, Azadeh Tarafdari, Mohammadamin Parsaei   +7 more
doaj   +1 more source

Status and future of recombinant adeno‐associated virus vector manufacturing

Biotechnology Progress, EarlyView.
Abstract Sixty years of adeno‐associated virus (AAV) research illustrates a trajectory marked by basic science exploration, iterative innovation, persistent challenges, a number of clinical setbacks, as well as commercial therapeutic triumphs. This continual evolution has led to recombinant AAV (rAAV) becoming a cornerstone of modern gene therapy ...
Frank Agbogbo, David Dismuke
wiley   +1 more source

Positional Relationship Between the Orbicularis Oculi and Zygomaticus Complex Muscles by Ultrasonography: New Anatomical Insights for Crow's Feet Injection

Clinical Anatomy, EarlyView.
ABSTRACT The orbicularis oculi muscle (OOc) is strongly associated with facial aging as its contraction causes the formation of crow's feet. Botulinum neurotoxin (BoNT) injection is a representative treatment targeting muscle. The aim of this study was to demonstrate the anatomical relationship between the OOc and the zygomaticus complex muscles, and ...
Jiong‐Zhen Piao, Ji‐Hyun Lee, Kyung‐Seok Hu, Hee‐Jin Kim   +3 more
wiley   +1 more source

A comparison of neonatal outcomes after taking progesterone pills and progesterone intramuscular injections in preterm labor: An RCT. [PDF]

Int J Reprod Biomed, 2023
Dalili M, Barkhori-Mehni M, Karami Robati F.   +2 more
europepmc   +1 more source

Effects of Intramuscular Injections of Glycosaminoglycan Polysulfates on Signs of Incipient Hip Dysplasia in Growing Dogs [PDF]

, 1992
38 pages, 1 article*Effects of Intramuscular Injections of Glycosaminoglycan Polysulfates on Signs of Incipient Hip Dysplasia in Growing Dogs* (Lust, George; Williams, Alma J.; Burton-Wurster, Nancy; Beck, Kathy A.; Rubin, Gail) 38 ...
Williams, Alma J., Rubin, Gail, Beck, Kathy A., Lust, George, Burton-Wurster, Nancy, Cornell University. Dept. of Biological Statistics and Computational Biology., Cornell University. Biometrics Unit., Cornell University. Dept. of Biometrics.   +7 more
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