Results 51 to 60 of about 96,889 (339)

Efficacy of Thermotherapy to Treat Cutaneous Leishmaniasis Caused by Leishmania tropica in Kabul, Afghanistan: A Randomized, Controlled Trial [PDF]

, 2005
BACKGROUND: Pentavalent antimony is the agent recommended for treatment of cutaneous leishmaniasis (CL). Its use is problematic, because it is expensive and because of the potential for drug-associated adverse effects during a lengthy and painful ...
Aram H, Arana BA, Babajev KB, Berman JD, Berman JD, C. R. Davies, J. Kolaczinski, J. R. David, Junaid AJN, M. Bismullah, M. Mohsen, M. Wahid, Navin TR, Neva FA, Noyes H, R. J. Quinnell, R. Reithinger, Reithinger R, Rodriguez ME, Sacks DL, Sharquie KE, Tallab TM, Velasco-Castrejon O, World Health Organization   +23 more
core   +1 more source

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

Advanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode, Christian Ortiz, Tadeh Derstepanian, Natalia Vargas‐Montoya, Priyal Patel, Nikita Khadse, Saikat Manna, Ryan Landis, Joseph Skaleski, Lianne Boeglin, Hongfeng Deng, Anusha Dias, Hong Wang, Debora Barreiros Petropolis, Barak Yahalom, Shrirang Karve, Frank DeRosa   +16 more
wiley   +1 more source

Community Health Workers as Social Marketers of Injectable Contraceptives: A Case Study from Ethiopia. [PDF]

, 2017
Ethiopia has made notable progress in increasing awareness and knowledge of family planning and is considered a success story among funders and program planners.
Bell, Suzanne, Gessessew, Amanuel, Godefay, Hagos, Prata, Ndola, Weidert, Karen   +4 more
core   +2 more sources

Serotonergic System‐Targeted Nucleic Acid Hydrogel Coordinates Excitability Restoration and Circuit Reconstruction for Spinal Cord Injury Therapy

Advanced Materials, EarlyView.
The study reports a DNA/RNA heteroduplex hydrogel (SeroPTEN‐CG) that undergoes DNase‐mediated hydrogel‐to‐nanogel transition for spinal cord injury therapy by targeting the serotonergic system, combining 5‐hydroxytryptamine (5‐HT)‐mediated excitability restoration to reactivate dormant interneurons with phosphatase and tensin homolog (PTEN)‐targeted ...
Chunlin Li, Xiaoqing Zhao, Kai Jiang, Haixia Kang, Shuo Liu, Linlin Jiang, Baoshuai Bai, Haonan Cui, Ziyang Zhang, Menglei Dong, Ruizhi Zhang, Chenbo Zou, Shenghui Shang, Chi Zhang, Xiangchuang Fan, Lijuan Zhu, Huiquan Duan, Chuan Zhang, Shiqing Feng, Hengxing Zhou   +19 more
wiley   +1 more source

Multipl MRSA Absesses Following Intramuscular Injection a Case Report

Namık Kemal Tıp Dergisi
Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) cases are rarely reported. In this article, we present a patient who had no history of disease or risk factors for MRSA but developed multiple MRSA abscesses after receiving ...
Bahar Büşra ÖZKAN, Özgür GÜNAL, Hatice ÜDÜRGÜCÜ, Süleyman Sırrı KILIÇ   +3 more
doaj   +1 more source

Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao, Akmal Hidayat Bin Sabri, Mary B. McGuckin, Linlin Li, Zihao Wang, Eneko Larrañeta, Ryan F. Donnelly   +6 more
wiley   +1 more source

ESTUDO EXPERIMENTAL DAS RELAÇÕES TECLDUAIS EM RATOS, PROVOCADAS POR DIFERENTES CONCENTRAÇÕES DE PENICILINA G. BENZATINA

Revista da Escola de Enfermagem da USP
A procura de respostas científicas aos problemas decorrentes de procedimentos que envolvem ações profissionais constituem um desafio constante aos enfermeiros comprometidos com a melhoria do cuidado de enfermagem.
Mara Rita Rodrigues Massad, Eduardo Massad, Edna Apparecida Moura Arcuri   +2 more
doaj   +1 more source

Ensaio clínico randomizado para avaliação de dor e hematoma em administração de medicamentos por via subcutânea e intramuscular: há necessidade de troca de agulhas? [PDF]

, 2011
This clinical trial aimed at comparing the intensity of pain and bruising by subcutaneous and intramuscular injections using and retractable fixed syringes and needles and syringes with no needles combined, at a public hospital in São Paulo, for six ...
Ferreira, Barbara Carvalho, Lamblet, Luiz Carlos Ribeiro, Martucchi, Sergio Dias, Meira, Edilson Sant'Anna, Torres, Silvana   +4 more
core   +5 more sources

Flexible Sensor‐Based Human–Machine Interfaces with AI Integration for Medical Robotics

Advanced Robotics Research, EarlyView.
This review explores how flexible sensing technology and artificial intelligence (AI) significantly enhance human–machine interfaces in medical robotics. It highlights key sensing mechanisms, AI‐driven advancements, and applications in prosthetics, exoskeletons, and surgical robotics.
Yuxiao Wang, Zhipeng Jiang, Sun Hwa Kwon, Matthew Ibrahim, Alexander Dang, Lin Dong   +5 more
wiley   +1 more source

Rational Design of Optical Single‐Walled Carbon Nanotube‐Based Nanosensors with Biological Recognition Elements

Advanced Sensor Research, EarlyView.
This Review focuses on assessing and providing perspective on the field of rationally‐designed optical sensors constructed with single‐walled carbon nanotubes. The literature is reviewed and evaluated for SWCNT‐based sensors constructed with biomolecular recognition elements, including proteins, peptides, and oligonucleotides, as well as their methods ...
Amelia K. Ryan, Atara Israel, Maria Celina Stefoni, Catarina Ferraz, Ryan M. Williams   +4 more
wiley   +1 more source