Results 131 to 140 of about 126,057 (248)

Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review

British Journal of Pharmacology, EarlyView.
Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos, Stavros Topouzis, Steve P. H. Alexander, Miriam M. Cortese‐Krott, Zsuzsanna Helyes, Kirill Martemyanov, Claudio Mauro, Nithyanandan Nagercoil, Reynold A. Panettieri Jr, Hemal H. Patel, Rainer Schulz, Barbara Stefanska, Gary J. Stephens, Nathalie Vergnolle, Xin Wang, Stephen Ward, Péter Ferdinandy   +16 more
wiley   +1 more source

Prospective randomized control trial measuring posterior capsular opacification rates and visual outcomes following insertion of two monofocal intraocular lenses: the hydrophobic RayOne 800C and the hydrophilic RayOne 600C: 12-month results. [PDF]

J Cataract Refract Surg
Naderi K, Naderi K, Jameel A, Lam CFJ, Low S, Wagh V, Bhogal M, Ritchie A, Robbie S, Hammond C, Mohamed M, Stanojcic N, Azan E, Mann S, Hull C, O'Brart D.   +15 more
europepmc   +1 more source

Presenting Clinical Features of Vitreoretinal Lymphoma

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background Vitreoretinal lymphoma is a rare cancer, widely recognised to present diagnostic challenges. We aimed to report information that would support the clinician in considering this diagnosis. Methods We interrogated the International Vitreoretinal B‐Cell Lymphoma Registry for clinical data from patients newly diagnosed with ...
The International Vitreoretinal B‐Cell Lymphoma Registry Investigator Group, Mara Albert‐Fort, Sofia Androudi, Neni Anggraini, Atitaya Apivatthakakul, J. Fernando Arevalo, Meghan K. Berkenstock, Ester Carreño, Anita S.Y. Chan, Soon‐Phaik Chee, Fred K. Chen, Janejit Choovuthayakorn, Luca Cimino, Elisa E. Cornish, Gábor G. Deák, Alexandra L. Farrall, Christina J. Flaxel, Marion Funk, Zsuzsanna Gehl, Pietro Gentile, Debra A. Goldstein, John A. Gonzales, Fabrizio Gozzi, Antonio Hernández‐Pons, Samar Issa, Timothy M. Janetos, Hyeong Min Kim, Min Kim, Jared E. Knickelbein, Zachary A. Kroeger, Paradee Kunavisarut, Rina La Distia Nora, Seung Min Lee, Lyndell L. Lim, Ming Lee Lin, Victor Llorenç, Yunhua Loo, Lucía Martínez‐Costa, Janet M. Matthews, Peter J. McCluskey, David L. McKay, Matteo Menean, Elisabetta Miserocchi, Manabu Mochizuki, Rachael L. Niederer, Roderick F. O’day, Amy S. Pai, Alan G. Palestine, Kessara Pathanapitoon, Mark H.B. Radford, Josephine Richards, Sukhum Silpa‐archa, Joanne L. Sims, Justine R. Smith, Robert T. Swan, Yukiko Terada, Daniel V. Vasconcelos‐Santos, Anagha Vaze, Samanthila Waduthantri, Travers R.E. Weaver, Keryn L. Williams, Se Joon Woo, Richard J. Woodman, Frances Wu, Christine Younan   +64 more
wiley   +1 more source

Two-Stage Approach and Minimally Invasive Vitrectomy for Severe Ocular Perforation Injury: A Case Report. [PDF]

Am J Case Rep
Li W, Mao J.
europepmc   +1 more source

Twelve‐Month Real‐World Outcomes of Faricimab for Treatment‐Naive Neovascular AMD in Australia

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background To provide insights into the effectiveness and safety of faricimab for treatment‐naïve eyes with neovascular age‐related macular degeneration (nAMD). Methods A retrospective cohort study using a prospectively‐designed registry. Treatment‐naïve eyes with nAMD in Australia starting treatment with faricimab between Jan 2023–Sep 2024 ...
Mark Gillies, Yohei Hashimoto, Rahman Nazari, Jennifer Arnold, Beibei Wang, Richard Barry, Ross Ferrier, Justin Game, Daniel Barthelmes   +8 more
wiley   +1 more source

Prognostic Factors in Patients With Submacular Haemorrhage Complicating Age‐Related Macular Degeneration: A Post Hoc Analysis of the STAR Study

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background To investigate prognostic factors of recent submacular haemorrhage (SMH) complicating neovascular age‐related macular degeneration (nAMD) treated with surgery or pneumatic displacement combined with intravitreal injection of anti‐vascular endothelial growth factor.
Pierre‐Henry Gabrielle, Petra Eid, Ludwig Serge Aho, Laurent Kodjikian, Eric Souied, Joel Uzzan, Jean Baptiste Conart, Marie‐Noëlle Delyfer, Catherine Creuzot‐Garcher   +8 more
wiley   +1 more source

Association Between Intraocular Pressure Changes and Optic Nerve Head and Macular Perfusion Parameters During Isometric Exercise: OCTA Study. [PDF]

Diagnostics (Basel)
Krobot Čutura N, Čutura DM, Mrak M, Petric Vicković I, Ružić L.   +4 more
europepmc   +1 more source

Intraocular Metastasis: Differential Diagnosis and Management

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Intraocular metastases represent the most common type of malignant intraocular tumour in adults. These commonly affect the choroid but can also involve the iris, ciliary body, retina, vitreous, optic disc or lens. Breast and lung cancer are the most common origins of intraocular metastases.
Genovefa Μachairoudia, Dimitrios Kazantzis, Guy S. Negretti, Mandeep S. Sagoo   +3 more
wiley   +1 more source

Capsular bag folding associated with in-the-bag intraocular lens displacement in pseudoexfoliation syndrome [PDF]

Revista Brasileira de Oftalmologia
Ángela Martínez Sobrino, María Luna del Castillo, Herman Casado Blanco   +2 more
doaj   +1 more source

Prediction of intraocular pressure reduction after phacoemulsification surgery: A prospective observational study. [PDF]

Medicine (Baltimore)
Karabulut S, Karabulut M.
europepmc   +1 more source