Results 41 to 50 of about 7,048 (194)

Randomized, single‐centre, double‐blinded repeated dose investigation of safety and tolerability of ocular administrations of a novel silica eye drop product in healthy volunteers

Acta Ophthalmologica, EarlyView.
Abstract Purpose Managing ocular diseases often requires frequent eye drop administration, which can challenge patient compliance. A long‐acting eye drop technology using an amorphous synthetic silica composite was developed to address this. Our study aimed to assess the safety and tolerability of the Silica Eye Drop platform in healthy volunteers over
Aleksandra Poluianova, Marceline N. Akieh‐Pirkanniemi, Arto Hartikainen, Hanna Arstila, Kai Kaarniranta, Lasse Leino   +5 more
wiley   +1 more source

Aniridia‐associated keratopathy: Clinical and molecular mechanisms of disease progression and emerging therapeutic targets

Acta Ophthalmologica, EarlyView.
Abstract Congenital aniridia is a rare genetic disorder primarily caused by pathogenic variants of the PAX6 gene. It leads to various panocular anomalies, including aniridia‐associated keratopathy (AAK). This review highlights recent insights into its pathogenesis, focusing on clinical staging, microstructural changes in the cornea and molecular ...
N. Szentmáry, S. Suiwal, M. Amini, F. N. Fries, A. Náray, L. Latta, Z. Li, S. Li, S. Liu, S. L. Hsu, S. Kundu, G. Tóth, S. Trusen, J. Zimmermann, B. Seitz, B. Käsmann‐Kellner, Z. Hoxha, A. Langenbucher, O. Stachs, M. Cortón‐Perez, K. Tory, A. Csorba, Z. Z. Nagy, M. C. Acosta, J. Gallar, M. Csidey, E. Maka, T. Stachon   +27 more
wiley   +1 more source

Intralenticular Cilia Following Penetrating Ocular Trauma: A Case Report [PDF]

Iranian Journal of Medical Sciences, 2019
Penetrating ocular trauma is one of the most important causes of vision loss, especially in men, and can be associated with intraocular foreign bodies. The incidence of intraocular cilia after trauma is very low.
Aidin Meshksar, Ali Azimi
doaj   +1 more source

Cost effectiveness of treatments for wet age-related macular degeneration [PDF]

, 2011
Age-related macular degeneration (AMD) is a leading cause of blindness in people aged >= 50 years. Wet AMD in particular has a major impact on patient quality of life and imposes substantial burdens on healthcare systems.
Annemans, Lieven, Gallagher, Meghan, Mitchell, Paul, Thomas, Simu, White, Richard   +4 more
core   +1 more source

Antibiotic‐mediated immune modulation in periodontitis

Periodontology 2000, EarlyView.
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez, R. M. Arce, Camila Pinheiro Furquim, Cristiane Gonçalves, Alpdogan Kantarci, Magda Feres, Nidia C. Castro dos Santos   +6 more
wiley   +1 more source

Role Of Point Of Care Ultrasound In The Diagnosis Of Retinal Detachment In The Emergency Department. [PDF]

, 2019
Ocular complaints represent up to 3% of all emergency department (ED) visits. These presentations can result in permanent vision loss if not promptly diagnosed and treated.
Ali, Qumber, Fox, John C, Lahham, Shadi, Lee, Clifton, Palileo, Bea Martina   +4 more
core  

The use of a “horizontal centrifugation protocol” to prepare autologous platelet‐rich fibrin membranes for corneal reconstruction surgery in dogs with complicated corneal ulcerations: A case series

Veterinary Ophthalmology, Volume 28, Issue 2, Page 175-189, March 2025.
Abstract Objective The purpose of this case series was to describe the effect of autologous PRF membrane for corneal reconstruction surgery in dogs. PRF membranes made from two healthy dogs unrelated to the current case series were used for PRF histologic analyses. Animals Seven dogs with complicated corneal ulcerations. Procedure A complete ophthalmic
Louise Baadsgaard Bruun, Tommy A. Waskiw Hardon, Anne K. Havnsøe Krogh, Klaus Qvortup, Steffen Heegaard, Annemarie Thuri Kristensen, Michala de Linde Henriksen   +6 more
wiley   +1 more source

Intraorbital organic foreign body: computed tomography and management [PDF]

, 2001
Purpose: The clinical presentation of orbital foreign bodies is variable. The management and prognosis depends on the composition, location and if there is or not secondary infection.
Casanova, Fábio Henrique Cacho, Manso, Paulo Gois, Mello Filho, Paulo Augusto de Arruda, Nakanami, Deise Mitsuko   +3 more
core   +2 more sources

Reconstruction of deep and perforating corneal defects in dogs—A review (Part I/III): Autogenous ocular tissues, donor tissues, and corneal clarity scoring

Veterinary Ophthalmology, Volume 28, Issue 2, Page 519-531, March 2025.
Abstract Corneal reconstruction is a key part of veterinary ophthalmic practice and numerous reconstructive techniques have been described for use in small animals in the peer‐reviewed veterinary literature written in English. Despite the evidence accrued over the last six decades in over 40 clinical articles and numerous other publications on ocular ...
Rick F. Sanchez, Eric C. Ledbetter, Marta Leiva   +2 more
wiley   +1 more source

Biologia molecular aplicada ao diagnóstico laboratorial de endoftalmite bacteriana [PDF]

, 2009
Bacterial endophthalmitis is a serious but uncommon intraocular infection which frequently results in vision loss. Early diagnosis and appropriate therapy are associated with better visual outcome.
Bispo, Paulo José Martins, Hofling-Lima, Ana Luisa, Pignatari, Antonio Carlos Campos   +2 more
core   +3 more sources