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Immune-Mediated Intraocular Inflammation. Review
Czech and Slovak Ophthalmology, 2021Immune mediated inflammatory diseases are categorized into autoimmune and autoinflammatory. Autoimmune etiology is represented by autoreactive lymphocytes or autoantibodies, e.g. primary Sjögren‘s syndrome or rheumatoid arthritis. Ocular specific diseases with presumed autoimmune origin are sympathetic ophthalmia or birdshot chorioretinopathy ...
A, Klímová +4 more
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Cytokines and intraocular inflammation
Current Eye Research, 1990Although new endogenous mediators of inflammatory and immune responses are reported almost on a monthly basis, the cytokines IL-1, TNF, and IL-6 have emerged as the primary regulators of local inflammation in man. In this paper, uveitogenic and other properties of these particular cytokines are discussed and attention is payed to the possible ...
Hoekzema, R. +2 more
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Cytokines in human intraocular inflammation
Current Eye Research, 1992The presence of interleukin 6 (IL-6), interleukin 1 (IL-1), interleukin 2 (IL-2) and tumour necrosis factor (TNF) was investigated in vitreous and aqueous aspirates from eyes undergoing vitrectomy for the treatment of different inflammatory conditions. Cadaveric vitreous from 10 normal subjects were used as controls.
W A, Franks +6 more
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Intraocular Inflammation in Diabetic Populations
Current Diabetes Reports, 2017The purpose of this review is to determine the prevalence of uveitis in the diabetic population, the clinical features of the uveitis and diabetes when coexisting and pathophysiology of a possible correlation. We also aim to review the cases of diabetes and uveitis in the literature.The basis of an association between uveitis and diabetes mellitus (DM)
Wajiha J, Kheir +2 more
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Choroidal Osteoma After Intraocular Inflammation
American Journal of Ophthalmology, 1983A 12-year-old girl had blurred vision and pain behind her left eye for three months. An examination disclosed focal choroiditis and optic nerve edema. Her visual acuity was 20/30. Two similar previous episodes had been diagnosed as scleritis and uveitis and the patient was still on a regimen of 5 mg of prednisone per day and eyedrops containing ...
S N, Trimble, H, Schatz
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Intraocular inflammation in autoimmune diseases
Seminars in Arthritis and Rheumatism, 2004The uveal tract represents the vascular organ of the eye. In addition to providing most of the blood supply to the intraocular structures, it acts as a conduit for immune cells, particularly lymphocytes, to enter the eye. Consequently, the uveal tract is represented in many intraocular inflammatory processes.
Eran, Pras +6 more
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Association of Dupilumab with Intraocular Inflammation
Ocular Immunology and Inflammation, 2021To report four cases of uveitis after treatment with dupilumab for atopic dermatitis.Retrospective case series.Data was collected from four patients with inflammation that developed after treatment with dupilumab. The first patient was thought to have developed posterior scleritis or Harada's-type disease related to her treatment with dupilumab, with ...
Sneha, Padidam +4 more
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Human Immunoglobulins in Intraocular Inflammation
Annals of the New York Academy of Sciences, 2007Abstract: Chronic intraocular inflammation (IOI) is a heterogeneous group of rare diseases, which represents one of the leading causes of acquired and treatable blindness in adults. The main anatomical site of inflammation is the uveal tract, which is the vascular organ of the eye, but uveitis is now used to describe IOI more globally.
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Intraocular miotics and postoperative inflammation
Journal of Cataract and Refractive Surgery, 1993Sixty patients scheduled for planned extracapsular cataract extraction with intraocular lens (IOL) implantation were randomly assigned to receive acetylcholine chloride, carbachol, or balanced salt solution (BSS) immediately after IOL placement and at the end of the surgical case.
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Intraocular inflammation: Its causes and investigations
Current Allergy and Asthma Reports, 2008Intraocular inflammation, or uveitis, incorporates a diverse group of infectious and immune-mediated disorders. In addition, some conditions masquerade as uveitis. However, classifying uveitis according to anatomic location in adult and pediatric populations, and appreciating the effect of immune status and regional differences, refines the list of ...
Claire, Hooper, Peter, McCluskey
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