Results 121 to 130 of about 146,071 (300)

Randomized, single‐centre, double‐blinded repeated dose investigation of safety and tolerability of ocular administrations of a novel silica eye drop product in healthy volunteers

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose Managing ocular diseases often requires frequent eye drop administration, which can challenge patient compliance. A long‐acting eye drop technology using an amorphous synthetic silica composite was developed to address this. Our study aimed to assess the safety and tolerability of the Silica Eye Drop platform in healthy volunteers over
Aleksandra Poluianova   +5 more
wiley   +1 more source

Retinal oxygen saturation and retinal vessel diameter in glaucoma patients before and after trabeculectomy

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To compare retinal vessel oxygen saturations and diameters before, 1 and 3 months after trabeculectomy. Methods Retinal oxygen saturations and vessel diameters were obtained using retinal oximetry. The effect of the postoperative intraocular pressure (IOP) decrease on the arteriovenous difference (AV‐difference) was evaluated ...
S. Kemp   +5 more
wiley   +1 more source

Fania (Fanny) Kaplan and the attempted assassination of Vladimir Lenin: Ophthalmologic considerations

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose Fania (Fanny) Kaplan (1890–1918), who was reportedly visually impaired, confessed to the attempted assassination of Soviet leader Vladimir Lenin (1870–1924) in 1918 by shooting him with a pistol. The precise nature of her visual loss is unknown and raises doubts about whether she had sufficient visual function to perform the act ...
Stephen G. Schwartz   +3 more
wiley   +1 more source

Intraocular Pressure during Hemodialysis

open access: yesJournal of UOEH, 2000
Hemodialysis, a useful treatment for patients with severely compromised renal function, has also unfavorable side effects. In the ophthalmologic area, a rise in intraocular pressure (IOP) during dialysis accompanied by ocular pain has been reported. In our study when measuring IOP, as well as serum osmolality and plasma CO2 pressure every 30 minutes ...
openaire   +3 more sources

Impact of mono‐ or multitherapy on ocular surface health and quality of life after 5 years of follow‐up in the Glaucoma Intensive Treatment Study (GITS)

open access: yesActa Ophthalmologica, EarlyView.
Abstract Aim To evaluate the impact of initial mono‐ versus multitherapy on the ocular surface and related quality of life after 5 years follow‐up in the Glaucoma Intensive Treatment Study (GITS). Method The study included patients with primary open‐angle glaucoma and pseudoexfoliation glaucoma who completed 5‐year follow‐up in GITS.
Gauti Jóhannesson   +6 more
wiley   +1 more source

Astigmatic changes after Descemet membrane endothelial keratoplasty (DMEK) in decompensated penetrating keratoplasty grafts

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To evaluate the surgery‐induced changes of astigmatism after Descemet membrane endothelial keratoplasty (DMEK) in eyes with failed previous penetrating keratoplasty (PK). Design Retrospective, interventional cohort study based on prospective DMEK database.
Florian Thomas Steinberg   +6 more
wiley   +1 more source

Outcomes and complications of sponges versus tires for scleral buckling in primary rhegmatogenous retinal detachment: The Manchester Buckle Study

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To compare preoperative characteristics and postoperative anatomical and functional outcomes of scleral buckle surgery using sponges versus tires, as well as explant‐related complications and the frequency of explant removal. Methods This retrospective study included patients with primary rhegmatogenous retinal detachment (RRD) who ...
Peter Kiraly   +11 more
wiley   +1 more source

Single-cell RNA sequencing analysis of the retina under acute high intraocular pressure

open access: yesNeural Regeneration Research
High intraocular pressure causes retinal ganglion cell injury in primary and secondary glaucoma diseases, yet the molecular landscape characteristics of retinal cells under high intraocular pressure remain unknown. Rat models of acute hypertension ocular
Shaojun Wang   +7 more
doaj   +1 more source

Adherence, compliance, persistence and concordance in the management of glaucoma, Part I [PDF]

open access: yes, 2012
Adherence is laden with difficulties in relation to the management of glaucoma. Perhaps a significant issue associated with a lack of the aforementioned is associated with the patient's failure to recognize there is a need to administer their eye drops ...
Cox, C. L.
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