Recent Developments in the Optical Control of Adrenergic Signaling
Medicinal Research Reviews, EarlyView.ABSTRACT Adrenoceptors (ARs) play a vital role in various physiological processes and are key therapeutic targets. The advent of optical control techniques, including optogenetics and photopharmacology, offers the potential to modulate AR signaling with precise temporal and spatial resolution. In this review, we summarize the latest advancements in the
Shuang Shi +4 more
wiley +1 more source
3D Growth and Remodeling Theory Supports the Hypothesis of Staphyloma Formation from Local Scleral Weakening under Normal Intraocular Pressure [PDF]
arXiv$\bf{Purpose}$: To assess whether Growth & Remodeling (G&R) theory could explain staphyloma formation from a local scleral weakening. $\bf{Methods}$: A finite element model of a healthy eye was reconstructed, including the following connective tissues: the lamina cribrosa, the peripapillary sclera, and the peripheral sclera.
arxiv
Current Advances in the Combination of Fatty Acids and Resveratrol to Fight Ocular Diseases
Molecular Nutrition &Food Research, EarlyView.Graphical abstract illustrating the effects of Resvega administration on choroidal neovascularization and resveratrol metabolism in the retina. The diagram illustrates that oral administration of Resvega leads to a decrease in choroidal neovascularization.
Dominique Delmas +3 more
wiley +1 more source
Anæsthesia and intraocular pressure [PDF]
Anaesthesia, 1966 Aileen K. Adams, K.C. Barnett
openaire +3 more sources
Evaluation of In Vivo Subject-Specific Mechanical Modeling of the Optic Nerve Head for Robust Assessment of Ocular Mechanics [PDF]
arXivTo establish the tissue regions necessary to accurately represent the mechanics of the optic nerve head (ONH), imaging data of the ONH from 2 healthy subjects were used to create in vivo subject-specific eye mechanical models considering distinct properties for all major ocular tissues.
arxiv
Horner syndrome in a pediatric patient
Pediatric Investigation, EarlyView.Horner syndrome (HS) is a rare neurological disorder arising from disruption of the oculosympathetic pathway. paediatric HS is uncommon and may be congenital, however it is imperative that underlying sinister causes are excluded. ABSTRACT Introduction Horner syndrome (HS) is a rare neurological disorder arising from disruption of the oculosympathetic ...
Devansh Tandon +4 more
wiley +1 more source
Introducing the Biomechanics-Function Relationship in Glaucoma: Improved Visual Field Loss Predictions from intraocular pressure-induced Neural Tissue Strains [PDF]
arXivObjective. (1) To assess whether neural tissue structure and biomechanics could predict functional loss in glaucoma; (2) To evaluate the importance of biomechanics in making such predictions. Design, Setting and Participants. We recruited 238 glaucoma subjects.
arxiv
The vital role for nitric oxide in intraocular pressure homeostasis
Progress in retinal and eye research, 2020 Ester Reina-Torres +6 more
semanticscholar +1 more source
Ocular involvement in newly diagnosed pediatric leukemia: A systematic review and meta‐analysis
Pediatric Investigation, EarlyView.The global prevalence of ocular involvement in pediatric leukemia is estimated to be 20.32%, which is more common than previously recognized. Given the high rate of asymptomatic involvement, screening for all newly diagnosed leukemia patients is recommended.
Kristina Nazzicone +5 more
wiley +1 more source
Single-cell RNA sequencing analysis of the retina under acute high intraocular pressure
Neural Regeneration ResearchHigh intraocular pressure causes retinal ganglion cell injury in primary and secondary glaucoma diseases, yet the molecular landscape characteristics of retinal cells under high intraocular pressure remain unknown. Rat models of acute hypertension ocular
Shaojun Wang +7 more
doaj +1 more source