Results 51 to 60 of about 185,083 (353)

Systems genetics identifies a role for Cacna2d1 regulation in elevated intraocular pressure and glaucoma susceptibility [PDF]

, 2017
Glaucoma is a multi-factorial blinding disease in which genetic factors play an important role. Elevated intraocular pressure is a highly heritable risk factor for primary open angle glaucoma and currently the only target for glaucoma therapy.
Allingham, R. (Rand), Aung, T. (Tin), Bailey, J.N.C. (Jessica N. Cooke), Bonnemaijer, P. (Peter), Brilliant, M.H. (Murray H.), Budenz, D.L. (Donald L.), Cheng, C.-Y. (Cheng-Yu), Chintalapudi, S.R. (Sumana R.), Chuen Khor, C. (Chiea), Craig, J.E. (Jamie), Di Wang, X. (Xiang), Duijn, C.M. (Cornelia) van, Fingert, J. (John), Gaasterland, D. (Douglas), Gaasterland, T. (Terry), Gharahkhani, P. (Puya), Haines, J.L. (Jonathan), Hammond, C.J. (Christopher J.), Hark, L. (Lisa), Hauser, M.A. (Michael), Hee Kang, J. (Jae), Hewitt, A. (Alex), Hoehn, R. (Rene), Hysi, P.G. (Pirro), Iglesias Gonzalez, A. (Adriana), Igo Jr., R.P. (Robert), Jablonski, M.M. (Monica M.), Jonansson, F. (Fridbert), Khawaja, A.P. (Anthony), Klaver, C.C.W. (Caroline), Kraft, P. (Peter), Lee, R.K. (Richard K.), Lichter, P.A. (Paul A.), Liu, Y. (Yutao), Lotery, A.J. (Andrew), MacGregor, S. (Stuart), Mackey, D.A. (David), Maria, D. (Doaa), Moroi, S. (Syoko), Pang, C. (Calvin), Pasquale, L.R. (Louis), Pasutto, F. (Francesca), Pericak-Vance, M.A. (Margaret), Realini, A. (Anthony), Rhee, D. (Doug), Richards, J.R. (Julia R.), Ritch, R. (Robert), Schuman, J.S. (Joel S.), Scott, W.K. (William), Singh, K. (Kuldev), Sit, A.J. (Arthur J.), Thorleifsson, G. (Gudmar), Thorsteinsdottir, U. (Unnar), Vitart, V. (Veronique), Vithana, E.N. (Eranga), Vollrath, D. (Douglas), Wiggs, J.L. (Janey L.), Williams, R.W. (Robert W.), Wollstein, G. (Gadi), Young, T.L. (Terri L.), Zack, D.J. (Donald), Zeller, T. (Tanja), Zwart, J-A. (John-Anker)   +62 more
core   +1 more source

Solvent types used for the preparation of hydrogels determine their mechanical properties and influence cell viability through gelatine and calcium ions release

Journal of Biomedical Materials Research Part B: Applied Biomaterials, Volume 111, Issue 2, Page 314-330, February 2023., 2023
By the selection of the hydrogel composition, applied solvents, and concentration of the cross‐linking compound, it is possible to modify the properties of the materials designated for bioinks for 3D printing in Bone Tissue Engineering. Abstract Alginate‐gelatin hydrogels are the most commonly used materials for 3D bioprinting.
Karolina Rosińska, Mateusz Bartniak, Adrianna Wierzbicka, Anna Sobczyk‐Guzenda, Dorota Bociaga   +4 more
wiley   +1 more source

Evaluation of filtering blebs using the ‘Wuerzburg bleb classification score’ compared to clinical findings

BMC Ophthalmology, 2012
Background To determine the agreement between intraocular pressure and the ‘Wuerzburg bleb classification score’, as well as between single items of the score and intraocular pressure. Interobserver variability was analyzed.
Furrer Sandra, Menke Marcel N, Funk Jens, Töteberg-Harms Marc   +3 more
doaj   +1 more source

A Case of Cyclodialysis after Microhook Trabeculotomy Treated with Vitreous Surgery

Case Reports in Ophthalmology, 2021
We report a case of cyclodialysis with decreased visual acuity after microhook trabeculotomy (mTLO) successfully treated by vitreous surgery. A 41-year-old man had been medically treated for primary open-angle glaucoma in both eyes.
Takashi Kudo, Yukihiko Suzuki, Kodai Yamauchi, Toshio Tando, Kobu Adachi, Mitsuru Nakazawa   +5 more
doaj   +1 more source

Automatic Segmentation of the Optic Nerve Head Region in Optical Coherence Tomography: A Methodological Review [PDF]

arXiv, 2021
The optic nerve head represents the intraocular section of the optic nerve (ONH), which is prone to damage by intraocular pressure. The advent of optical coherence tomography (OCT) has enabled the evaluation of novel optic nerve head parameters, namely the depth and curvature of the lamina cribrosa (LC).
arxiv  

Intraocular Pressure Elevation in the Contralateral Untreated Eye Following Selective Laser Trabeculoplasty in Rabbit Eyes [PDF]

, 2015
Our study aimed at evaluating if a single session of unilateral selective laser trabeculoplasty would affect the intraocular pressure of the fellow untreated eye in rabbits. Eleven rabbits were involved.
Chiu, K, Choy, NKB, Lai, JSM, Shum, JWH
core   +1 more source

Ocular manifestations of psoriasis: An inflammatory disease beyond the skin

Journal of General and Family Medicine, Volume 24, Issue 1, Page 45-49, January 2023., 2023
Psoriasis can lead to meibomian gland dysfunction, especially in patients with long‐lasting disease. Hence, dermatologists and general practitioners should be vigilant in this regard when visiting psoriasis patients, especially those who have higher PASI values or long‐lasting disease.
Zeinab Aryanian, Azar Shirzadian, Parvaneh Hatami, Gholam abbas Roostayi, Sadrollah Najafi, Azadeh Goodarzi   +5 more
wiley   +1 more source

A Theoretical Study of Aqueous Humor Secretion Based on a Continuum Model Coupling Electrochemical and Fluid-Dynamical Transmembrane Mechanisms [PDF]

Commun. Appl. Math. Comput. Sci. 14 (2019) 65-103, 2017
Intraocular pressure, resulting from the balance of aqueous humor (AH) production and drainage, is the only approved treatable risk factor in glaucoma. AH production is determined by the concurrent function of ionic pumps and aquaporins in the ciliary processes but their individual contribution is difficult to characterize experimentally. In this work,
arxiv   +1 more source

GWAS-by-subtraction reveals an IOP-independent component of primary open angle glaucoma

Nature Communications
The etiology of primary open angle glaucoma is constituted by both intraocular pressure-dependent and intraocular pressure-independent mechanisms.
Yu Huang, Denis Plotnikov, Huan Wang, Danli Shi, Cong Li, Xueli Zhang, Xiayin Zhang, Shulin Tang, Xianwen Shang, Yijun Hu, Honghua Yu, Hongyang Zhang, Jeremy A. Guggenheim, Mingguang He   +13 more
doaj   +1 more source

A Wireless Wearable Sensor System Based on a Silver Nanowire‐Decorated Silicon Nanomembrane for Precise and Continuous Hazardous Gas Monitoring

Advanced Functional Materials, EarlyView.
Silver nanowire‐decorated silicon nanomembrane (AgNW‐SiNM) wireless wearable gas sensor exhibits a high response of ≈1.83 upon exposure to 10 ppm NH3. A stacked structure of the AgNW‐SiNM gas sensor with a flexible Joule heater improves the recovery rate after gas exposure.
Jongwoon Shin, Kyubeen Kim, In Sik Min, Mingyu Sang, Ju Young Lee, Kyuhyun Hwang, Yunsung Kang, Jongbaeg Kim, Ki Jun Yu   +8 more
wiley   +1 more source